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    SPEG striated muscle enriched protein kinase [ Homo sapiens (human) ]

    Gene ID: 10290, updated on 9-Dec-2024

    Summary

    Official Symbol
    SPEGprovided by HGNC
    Official Full Name
    striated muscle enriched protein kinaseprovided by HGNC
    Primary source
    HGNC:HGNC:16901
    See related
    Ensembl:ENSG00000072195 MIM:615950; AllianceGenome:HGNC:16901
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    BPEG; CNM5; APEG1; MYLK6; APEG-1; SPEGbeta; SPEGalpha
    Summary
    This gene encodes a protein with similarity to members of the myosin light chain kinase family. This protein family is required for myocyte cytoskeletal development. Along with the desmin gene, expression of this gene may be controlled by the desmin locus control region. Mutations in this gene are associated with centronuclear myopathy 5. [provided by RefSeq, Jun 2016]
    Expression
    Broad expression in endometrium (RPKM 4.8), prostate (RPKM 4.5) and 17 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See SPEG in Genome Data Viewer
    Location:
    2q35
    Exon count:
    49
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (219434843..219493629)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (219919623..219978369)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (220299565..220358351)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene aspartyl aminopeptidase Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12356 Neighboring gene DNPEP antisense RNA 1 Neighboring gene desmin locus control region Neighboring gene VISTA enhancer hs2169 Neighboring gene desmin Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:220313846-220314453 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:220315912-220316716 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:220317062-220318261 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:220325404-220325584 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:220329861-220330528 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:220330529-220331194 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:220331442-220331984 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:220339972-220340679 Neighboring gene Sharpr-MPRA regulatory region 8597 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:220341387-220342094 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:220348981-220349782 Neighboring gene ASIC4 antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 15624 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:220361035-220361852 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:220361853-220362670 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:220362671-220363488 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17153 Neighboring gene SPEG neighbor Neighboring gene GDP-mannose pyrophosphorylase A

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA1297, MGC12676

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables 3-phosphoinositide-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables AMP-activated protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables Rho-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables eukaryotic translation initiation factor 2alpha kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AS1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AS121 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AT120 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AXS139 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2BS14 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2BS36 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3S10 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3S28 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3S57 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3T11 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3T3 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3T45 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3T6 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H4S1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ribosomal protein S6 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in muscle cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in muscle organ development TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in negative regulation of cell population proliferation TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    striated muscle preferentially expressed protein kinase
    Names
    SPEG complex locus
    aortic preferentially expressed gene 1
    aortic preferentially expressed protein 1
    nuclear protein, marker for differentiated aortic smooth muscle and down-regulated with vascular injury
    NP_001166947.1
    NP_005867.3
    XP_005246294.1
    XP_005246296.1
    XP_005246297.1
    XP_005246298.1
    XP_005246299.1
    XP_006712252.1
    XP_006712256.1
    XP_011508781.1
    XP_016858648.2
    XP_016858650.2
    XP_016858651.2
    XP_024308294.2
    XP_047298847.1
    XP_047298848.1
    XP_047298849.1
    XP_047298850.1
    XP_047298851.1
    XP_047298852.1
    XP_047298853.1
    XP_047298854.1
    XP_047298856.1
    XP_047298857.1
    XP_047298858.1
    XP_047298859.1
    XP_047298860.1
    XP_047298861.1
    XP_047298862.1
    XP_047298863.1
    XP_047298864.1
    XP_047298865.1
    XP_047298866.1
    XP_047298867.1
    XP_047298868.1
    XP_047298870.1
    XP_047298873.1
    XP_047298874.1
    XP_047298875.1
    XP_047298876.1
    XP_047298877.1
    XP_047298878.1
    XP_047298879.1
    XP_054196108.1
    XP_054196109.1
    XP_054196110.1
    XP_054196111.1
    XP_054196112.1
    XP_054196113.1
    XP_054196114.1
    XP_054196115.1
    XP_054196116.1
    XP_054196117.1
    XP_054196118.1
    XP_054196119.1
    XP_054196120.1
    XP_054196121.1
    XP_054196122.1
    XP_054196123.1
    XP_054196124.1
    XP_054196125.1
    XP_054196126.1
    XP_054196127.1
    XP_054196128.1
    XP_054196129.1
    XP_054196130.1
    XP_054196131.1
    XP_054196132.1
    XP_054196133.1
    XP_054196134.1
    XP_054196135.1
    XP_054196136.1
    XP_054196137.1
    XP_054196138.1
    XP_054196139.1
    XP_054196140.1
    XP_054196141.1
    XP_054196142.1
    XP_054196143.1
    XP_054196144.1
    XP_054196145.1
    XP_054196146.1
    XP_054196147.1
    XP_054196148.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_051022.1 RefSeqGene

      Range
      5629..64415
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001173476.2NP_001166947.1  striated muscle preferentially expressed protein kinase isoform 4

      See identical proteins and their annotated locations for NP_001166947.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) has multiple differences, compared to variant 1. These differences result in a distinct 5' UTR and cause translation initiation at a downstream start codon, compared to variant 1. The encoded protein (isoform 4) is shorter than isoform 1. This variant corresponds to the mouse APEG-1 variant described in PubMed ID: 10973969.
      Source sequence(s)
      AC053503, BM677138, DA063220
      Consensus CDS
      CCDS54432.1
      UniProtKB/Swiss-Prot
      Q15772
      Related
      ENSP00000379919.1, ENST00000396688.5
      Conserved Domains (2) summary
      cd00096
      Location:2022
      Ig; Ig strand A [structural motif]
      cl11960
      Location:20110
      Ig; Immunoglobulin domain
    2. NM_005876.5NP_005867.3  striated muscle preferentially expressed protein kinase isoform 1

      See identical proteins and their annotated locations for NP_005867.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1). This variant corresponds to the mouse SPEGbeta variant described in PubMed ID: 10973969.
      Source sequence(s)
      AC053503
      Consensus CDS
      CCDS42824.1
      UniProtKB/Swiss-Prot
      A8K0G6, A8MRU0, Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9
      Related
      ENSP00000311684.7, ENST00000312358.12
      Conserved Domains (8) summary
      cd00096
      Location:15021571
      Ig; Immunoglobulin domain
      smart00408
      Location:882949
      IGc2; Immunoglobulin C-2 Type
      smart00220
      Location:29663218
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam07679
      Location:722811
      I-set; Immunoglobulin I-set domain
      cd14108
      Location:15981854
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:29623218
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:812868
      SPEG_u2; Unstructured region on SPEG complex protein
      cl11960
      Location:745812
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      219434843..219493629
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047442891.1XP_047298847.1  striated muscle preferentially expressed protein kinase isoform X2

    2. XM_011510479.3XP_011508781.1  striated muscle preferentially expressed protein kinase isoform X1

      Conserved Domains (8) summary
      cd00096
      Location:15121581
      Ig; Immunoglobulin domain
      smart00408
      Location:892959
      IGc2; Immunoglobulin C-2 Type
      smart00220
      Location:29763228
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam07679
      Location:732821
      I-set; Immunoglobulin I-set domain
      cd14108
      Location:16081864
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:29723228
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:822878
      SPEG_u2; Unstructured region on SPEG complex protein
      cl11960
      Location:755822
      Ig; Immunoglobulin domain
    3. XM_047442893.1XP_047298849.1  striated muscle preferentially expressed protein kinase isoform X4

    4. XM_047442892.1XP_047298848.1  striated muscle preferentially expressed protein kinase isoform X3

    5. XM_047442894.1XP_047298850.1  striated muscle preferentially expressed protein kinase isoform X5

    6. XM_047442895.1XP_047298851.1  striated muscle preferentially expressed protein kinase isoform X8

    7. XM_017003159.3XP_016858648.2  striated muscle preferentially expressed protein kinase isoform X12

    8. XM_047442901.1XP_047298857.1  striated muscle preferentially expressed protein kinase isoform X15

    9. XM_017003161.3XP_016858650.2  striated muscle preferentially expressed protein kinase isoform X16

    10. XM_017003162.3XP_016858651.2  striated muscle preferentially expressed protein kinase isoform X17

    11. XM_024452526.2XP_024308294.2  striated muscle preferentially expressed protein kinase isoform X19

    12. XM_047442902.1XP_047298858.1  striated muscle preferentially expressed protein kinase isoform X18

    13. XM_047442906.1XP_047298862.1  striated muscle preferentially expressed protein kinase isoform X23

    14. XM_047442903.1XP_047298859.1  striated muscle preferentially expressed protein kinase isoform X20

    15. XM_005246239.3XP_005246296.1  striated muscle preferentially expressed protein kinase isoform X11

      Conserved Domains (8) summary
      cd00096
      Location:710779
      Ig; Immunoglobulin domain
      smart00408
      Location:90157
      IGc2; Immunoglobulin C-2 Type
      smart00220
      Location:21742426
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam07679
      Location:693782
      I-set; Immunoglobulin I-set domain
      cd14108
      Location:8061062
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:21702426
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:2076
      SPEG_u2; Unstructured region on SPEG complex protein
      cl11960
      Location:413485
      Ig; Immunoglobulin domain
    16. XM_047442898.1XP_047298854.1  striated muscle preferentially expressed protein kinase isoform X11

    17. XM_005246237.3XP_005246294.1  striated muscle preferentially expressed protein kinase isoform X6

      Conserved Domains (8) summary
      cd00096
      Location:14081477
      Ig; Immunoglobulin domain
      smart00408
      Location:788855
      IGc2; Immunoglobulin C-2 Type
      smart00220
      Location:28723124
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam07679
      Location:628717
      I-set; Immunoglobulin I-set domain
      cd14108
      Location:15041760
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:28683124
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:718774
      SPEG_u2; Unstructured region on SPEG complex protein
      cl11960
      Location:651718
      Ig; Immunoglobulin domain
    18. XM_047442896.1XP_047298852.1  striated muscle preferentially expressed protein kinase isoform X9

    19. XM_006712189.4XP_006712252.1  striated muscle preferentially expressed protein kinase isoform X7

      Conserved Domains (8) summary
      cd00096
      Location:13981467
      Ig; Immunoglobulin domain
      smart00408
      Location:778845
      IGc2; Immunoglobulin C-2 Type
      smart00220
      Location:28623114
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam07679
      Location:618707
      I-set; Immunoglobulin I-set domain
      cd14108
      Location:14941750
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:28583114
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:708764
      SPEG_u2; Unstructured region on SPEG complex protein
      cl11960
      Location:641708
      Ig; Immunoglobulin domain
    20. XM_047442897.1XP_047298853.1  striated muscle preferentially expressed protein kinase isoform X10

    21. XM_047442917.1XP_047298873.1  striated muscle preferentially expressed protein kinase isoform X31

    22. XM_047442919.1XP_047298875.1  striated muscle preferentially expressed protein kinase isoform X31

    23. XM_047442922.1XP_047298878.1  striated muscle preferentially expressed protein kinase isoform X32

    24. XM_047442918.1XP_047298874.1  striated muscle preferentially expressed protein kinase isoform X31

    25. XM_047442921.1XP_047298877.1  striated muscle preferentially expressed protein kinase isoform X32

    26. XM_047442920.1XP_047298876.1  striated muscle preferentially expressed protein kinase isoform X31

    27. XM_047442923.1XP_047298879.1  striated muscle preferentially expressed protein kinase isoform X32

    28. XM_047442904.1XP_047298860.1  striated muscle preferentially expressed protein kinase isoform X21

    29. XM_047442908.1XP_047298864.1  striated muscle preferentially expressed protein kinase isoform X25

    30. XM_047442907.1XP_047298863.1  striated muscle preferentially expressed protein kinase isoform X24

    31. XM_047442912.1XP_047298868.1  striated muscle preferentially expressed protein kinase isoform X29

    32. XM_047442910.1XP_047298866.1  striated muscle preferentially expressed protein kinase isoform X27

    33. XM_047442905.1XP_047298861.1  striated muscle preferentially expressed protein kinase isoform X22

      UniProtKB/TrEMBL
      B9ZVR7
      Related
      ENSP00000379926.1, ENST00000396698.5
    34. XM_047442909.1XP_047298865.1  striated muscle preferentially expressed protein kinase isoform X26

    35. XM_047442914.1XP_047298870.1  striated muscle preferentially expressed protein kinase isoform X30

    36. XM_047442911.1XP_047298867.1  striated muscle preferentially expressed protein kinase isoform X28

    37. XM_047442900.1XP_047298856.1  striated muscle preferentially expressed protein kinase isoform X11

      Related
      ENST00000485813.5
    38. XM_006712193.4XP_006712256.1  striated muscle preferentially expressed protein kinase isoform X14

      See identical proteins and their annotated locations for XP_006712256.1

      Conserved Domains (7) summary
      cd00096
      Location:653722
      Ig; Immunoglobulin domain
      smart00408
      Location:33100
      IGc2; Immunoglobulin C-2 Type
      smart00220
      Location:21172369
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam07679
      Location:636725
      I-set; Immunoglobulin I-set domain
      cd14108
      Location:7491005
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:21132369
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cl11960
      Location:356428
      Ig; Immunoglobulin domain
    39. XM_005246240.2XP_005246297.1  striated muscle preferentially expressed protein kinase isoform X14

      See identical proteins and their annotated locations for XP_005246297.1

      Conserved Domains (7) summary
      cd00096
      Location:653722
      Ig; Immunoglobulin domain
      smart00408
      Location:33100
      IGc2; Immunoglobulin C-2 Type
      smart00220
      Location:21172369
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam07679
      Location:636725
      I-set; Immunoglobulin I-set domain
      cd14108
      Location:7491005
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:21132369
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cl11960
      Location:356428
      Ig; Immunoglobulin domain
    40. XM_005246241.2XP_005246298.1  striated muscle preferentially expressed protein kinase isoform X14

      See identical proteins and their annotated locations for XP_005246298.1

      Conserved Domains (7) summary
      cd00096
      Location:653722
      Ig; Immunoglobulin domain
      smart00408
      Location:33100
      IGc2; Immunoglobulin C-2 Type
      smart00220
      Location:21172369
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam07679
      Location:636725
      I-set; Immunoglobulin I-set domain
      cd14108
      Location:7491005
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:21132369
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cl11960
      Location:356428
      Ig; Immunoglobulin domain
    41. XM_005246242.5XP_005246299.1  striated muscle preferentially expressed protein kinase isoform X13

      Conserved Domains (8) summary
      cd00096
      Location:715784
      Ig; Immunoglobulin domain
      smart00408
      Location:95162
      IGc2; Immunoglobulin C-2 Type
      smart00220
      Location:21792431
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam07679
      Location:698787
      I-set; Immunoglobulin I-set domain
      cd14108
      Location:8111067
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:21752431
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:2781
      SPEG_u2; Unstructured region on SPEG complex protein
      cl11960
      Location:418490
      Ig; Immunoglobulin domain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      219919623..219978369
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054340134.1XP_054196109.1  striated muscle preferentially expressed protein kinase isoform X2

    2. XM_054340133.1XP_054196108.1  striated muscle preferentially expressed protein kinase isoform X1

    3. XM_054340136.1XP_054196111.1  striated muscle preferentially expressed protein kinase isoform X4

    4. XM_054340135.1XP_054196110.1  striated muscle preferentially expressed protein kinase isoform X3

    5. XM_054340137.1XP_054196112.1  striated muscle preferentially expressed protein kinase isoform X5

    6. XM_054340140.1XP_054196115.1  striated muscle preferentially expressed protein kinase isoform X8

    7. XM_054340145.1XP_054196120.1  striated muscle preferentially expressed protein kinase isoform X12

    8. XM_054340151.1XP_054196126.1  striated muscle preferentially expressed protein kinase isoform X15

    9. XM_054340152.1XP_054196127.1  striated muscle preferentially expressed protein kinase isoform X16

    10. XM_054340153.1XP_054196128.1  striated muscle preferentially expressed protein kinase isoform X17

    11. XM_054340155.1XP_054196130.1  striated muscle preferentially expressed protein kinase isoform X19

    12. XM_054340154.1XP_054196129.1  striated muscle preferentially expressed protein kinase isoform X18

    13. XM_054340159.1XP_054196134.1  striated muscle preferentially expressed protein kinase isoform X23

    14. XM_054340156.1XP_054196131.1  striated muscle preferentially expressed protein kinase isoform X20

    15. XM_054340138.1XP_054196113.1  striated muscle preferentially expressed protein kinase isoform X6

    16. XM_054340169.1XP_054196144.1  striated muscle preferentially expressed protein kinase isoform X31

    17. XM_054340168.1XP_054196143.1  striated muscle preferentially expressed protein kinase isoform X31

    18. XM_054340161.1XP_054196136.1  striated muscle preferentially expressed protein kinase isoform X25

    19. XM_054340165.1XP_054196140.1  striated muscle preferentially expressed protein kinase isoform X29

    20. XM_054340172.1XP_054196147.1  striated muscle preferentially expressed protein kinase isoform X32

    21. XM_054340144.1XP_054196119.1  striated muscle preferentially expressed protein kinase isoform X11

    22. XM_054340143.1XP_054196118.1  striated muscle preferentially expressed protein kinase isoform X11

    23. XM_054340141.1XP_054196116.1  striated muscle preferentially expressed protein kinase isoform X9

    24. XM_054340139.1XP_054196114.1  striated muscle preferentially expressed protein kinase isoform X7

    25. XM_054340142.1XP_054196117.1  striated muscle preferentially expressed protein kinase isoform X10

    26. XM_054340158.1XP_054196133.1  striated muscle preferentially expressed protein kinase isoform X22

      UniProtKB/TrEMBL
      B9ZVR7
    27. XM_054340167.1XP_054196142.1  striated muscle preferentially expressed protein kinase isoform X31

    28. XM_054340171.1XP_054196146.1  striated muscle preferentially expressed protein kinase isoform X32

    29. XM_054340170.1XP_054196145.1  striated muscle preferentially expressed protein kinase isoform X31

    30. XM_054340173.1XP_054196148.1  striated muscle preferentially expressed protein kinase isoform X32

    31. XM_054340157.1XP_054196132.1  striated muscle preferentially expressed protein kinase isoform X21

    32. XM_054340160.1XP_054196135.1  striated muscle preferentially expressed protein kinase isoform X24

    33. XM_054340163.1XP_054196138.1  striated muscle preferentially expressed protein kinase isoform X27

    34. XM_054340162.1XP_054196137.1  striated muscle preferentially expressed protein kinase isoform X26

    35. XM_054340166.1XP_054196141.1  striated muscle preferentially expressed protein kinase isoform X30

    36. XM_054340164.1XP_054196139.1  striated muscle preferentially expressed protein kinase isoform X28

    37. XM_054340146.1XP_054196121.1  striated muscle preferentially expressed protein kinase isoform X11

    38. XM_054340150.1XP_054196125.1  striated muscle preferentially expressed protein kinase isoform X14

    39. XM_054340148.1XP_054196123.1  striated muscle preferentially expressed protein kinase isoform X14

    40. XM_054340149.1XP_054196124.1  striated muscle preferentially expressed protein kinase isoform X14

    41. XM_054340147.1XP_054196122.1  striated muscle preferentially expressed protein kinase isoform X13