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    wdr76 WD repeat domain 76 [ Danio rerio (zebrafish) ]

    Gene ID: 570063, updated on 2-Nov-2024

    Summary

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    Official Symbol
    wdr76provided by ZNC
    Official Full Name
    WD repeat domain 76provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4513
    See related
    Ensembl:ENSDARG00000053554 AllianceGenome:ZFIN:ZDB-GENE-030131-4513
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7148605; wu:fd11f08
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in regulation of DNA damage checkpoint. Predicted to be active in nucleus. Orthologous to human WDR76 (WD repeat domain 76). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See wdr76 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (30201611..30209790)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (29930461..29938640)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene si:ch211-107o10.3 Neighboring gene microRNA 184-2 Neighboring gene zinc finger protein 710b Neighboring gene sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Common deregulated gene expression profiles and morphological changes in developing zebrafish larvae exposed to environmental-relevant high to low concentrations of glucocorticoids. Chen Q, et al. Chemosphere, 2017 Apr. PMID 28092764
    2. Thyrotroph embryonic factor regulates light-induced transcription of repair genes in zebrafish embryonic cells. Gavriouchkina D, et al. PLoS One, 2010 Sep 7. PMID 20830285, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    WD repeat-containing protein 76

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001198567.1 → NP_001185496.1  WD repeat-containing protein 76

      Status: PROVISIONAL

      Source sequence(s)
      CR356246
      UniProtKB/TrEMBL
      A0A8M1NW89, E7FER1
      Related
      ENSDARP00000070070.5, ENSDART00000075588.6
      Conserved Domains (3) summary
      COG2319
      Location:239 → 551
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:251 → 291
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:249 → 551
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      30201611..30209790
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021477578.2 → XP_021333253.1  WD repeat-containing protein 76 isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q1Q9
      Conserved Domains (2) summary
      sd00039
      Location:252 → 292
      7WD40; WD40 repeat [structural motif]
      cl25539
      Location:250 → 552
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394696.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      169553..178151
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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