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    lsm14ab LSM14A mRNA processing body assembly factor b [ Danio rerio (zebrafish) ]

    Gene ID: 406800, updated on 2-Nov-2024

    Summary

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    Official Symbol
    lsm14abprovided by ZNC
    Official Full Name
    LSM14A mRNA processing body assembly factor bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2462
    See related
    Ensembl:ENSDARG00000100553 AllianceGenome:ZFIN:ZDB-GENE-040426-2462
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55754; zgc:77202; wu:fc55d12
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in P-body assembly and stress granule assembly. Predicted to be located in cytoplasm. Predicted to be active in P-body. Orthologous to human LSM14A (LSM14A mRNA processing body assembly factor). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See lsm14ab in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (302845..325512)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (413624..436294)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene transcription initiation factor TFIID subunit 4 Neighboring gene transcription initiation factor TFIID subunit 4 Neighboring gene si:ch211-79l17.1 Neighboring gene ss18, like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. prpf4 is essential for cell survival and posterior lateral line primordium migration in zebrafish. Wang Y, et al. J Genet Genomics, 2018 Aug 20. PMID 30174136
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in P-body assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in stress granule assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    LSM14A mRNA processing body assembly factor b
    Names
    LSM14 homolog Ab
    LSM14A, SCD6 homolog Ab

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214772.2 → NP_999937.2  LSM14A mRNA processing body assembly factor b

      See identical proteins and their annotated locations for NP_999937.2

      Status: VALIDATED

      Source sequence(s)
      CU611056, CU627988
      UniProtKB/TrEMBL
      Q6P0B2, Q6PUR5
      Related
      ENSDARP00000139299.1, ENSDART00000160279.2
      Conserved Domains (2) summary
      pfam09532
      Location:260 → 376
      FDF; FDF domain
      pfam12701
      Location:6 → 80
      LSM14; Scd6-like Sm domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      302845..325512
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005158973.4 → XP_005159030.1  LSM14A mRNA processing body assembly factor b isoform X1

      UniProtKB/TrEMBL
      A0A0R4IVM1, A0A8M2B5Y4
      Related
      ENSDARP00000140356.1, ENSDART00000157434.2
      Conserved Domains (2) summary
      pfam09532
      Location:291 → 407
      FDF; FDF domain
      pfam12701
      Location:6 → 80
      LSM14; Scd6-like Sm domain

    2. XM_005158974.4 → XP_005159031.1  LSM14A mRNA processing body assembly factor b isoform X2

      UniProtKB/TrEMBL
      A0A8M2B5X3
      Conserved Domains (2) summary
      pfam09532
      Location:291 → 407
      FDF; FDF domain
      pfam12701
      Location:6 → 80
      LSM14; Scd6-like Sm domain

    3. XM_068214752.1 → XP_068070853.1  LSM14A mRNA processing body assembly factor b isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

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