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    scaf11 SR-related CTD-associated factor 11 [ Danio rerio (zebrafish) ]

    Gene ID: 566484, updated on 2-Nov-2024

    Summary

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    Official Symbol
    scaf11provided by ZNC
    Official Full Name
    SR-related CTD-associated factor 11provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041210-22
    See related
    Ensembl:ENSDARG00000045885 AllianceGenome:ZFIN:ZDB-GENE-041210-22
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sfrs2ip; srsf2ip; si:ch211-132p20.2
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in spliceosomal complex assembly. Orthologous to human SCAF11 (SR-related CTD associated factor 11). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See scaf11 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (1619574..1640356)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (1770227..1791043)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110439353 Neighboring gene solute carrier family 38 member 2 Neighboring gene AT-rich interactive domain 2 Neighboring gene growth arrest-specific 2 like 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene. Ding Y, et al. Elife, 2022 Oct 18. PMID 36255053, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in spliceosomal complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SFRS2-interacting protein; protein SCAF11
    Names
    serine/arginine-rich splicing factor 2, interacting protein
    splicing factor, arginine/serine-rich 2, interacting protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      1619574..1640356
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068220712.1 → XP_068076813.1  protein SCAF11 isoform X1

    2. XM_005164460.5 → XP_005164517.1  protein SCAF11 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BBX1, F1RBI7, Q5SPB2
      Related
      ENSDARP00000067443.8, ENSDART00000067444.8
      Conserved Domains (1) summary
      pfam13639
      Location:24 → 65
      zf-RING_2; Ring finger domain

    3. XM_005164461.5 → XP_005164518.1  protein SCAF11 isoform X2

      UniProtKB/TrEMBL
      A0A8M2BBM9
      Conserved Domains (1) summary
      pfam13639
      Location:24 → 65
      zf-RING_2; Ring finger domain

    4. XM_689753.9 → XP_694845.5  protein SCAF11 isoform X3

      UniProtKB/TrEMBL
      A0A8N7T6G1
      Related
      ENSDARP00000125045.1, ENSDART00000148486.2
      Conserved Domains (1) summary
      pfam13639
      Location:24 → 65
      zf-RING_2; Ring finger domain
    Nucleotide Protein
    Heading Accession and Version

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