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    Spint5 serine protease inhibitor, Kunitz type 5 [ Mus musculus (house mouse) ]

    Gene ID: 641368, updated on 9-Aug-2024

    Summary

    Official Symbol
    Spint5provided by MGI
    Official Full Name
    serine protease inhibitor, Kunitz type 5provided by MGI
    Primary source
    MGI:MGI:3651687
    See related
    Ensembl:ENSMUSG00000074593 AllianceGenome:MGI:3651687
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm14316
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be active in extracellular space. Orthologous to human SPINT5P (serine peptidase inhibitor, Kunitz type 5, pseudogene). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward genital fat pad adult (RPKM 61.3) See more
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    Genomic context

    See Spint5 in Genome Data Viewer
    Location:
    2 H3; 2 85.27 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (164557225..164559988)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (164715305..164718068)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene WAP four-disulfide core domain 13 Neighboring gene serine protease inhibitor, Kunitz type 4 Neighboring gene WAP four-disulfide core domain 3 Neighboring gene deoxynucleotidyltransferase, terminal, interacting protein 1 Neighboring gene STARR-seq mESC enhancer starr_06333

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General protein information

    Preferred Names
    serine protease inhibitor, Kunitz type 5
    Names
    KUNITZ5
    Spint5 (KUNITZ5)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001040055.1NP_001035144.1  serine protease inhibitor, Kunitz type 5 precursor

      See identical proteins and their annotated locations for NP_001035144.1

      Status: PROVISIONAL

      Source sequence(s)
      AY542490
      Consensus CDS
      CCDS17052.1
      UniProtKB/TrEMBL
      Q32ZM2
      Related
      ENSMUSP00000099386.4, ENSMUST00000103097.10
      Conserved Domains (1) summary
      smart00131
      Location:4899
      KU; BPTI/Kunitz family of serine protease inhibitors

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      164557225..164559988
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)