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    OR1D2 olfactory receptor family 1 subfamily D member 2 [ Homo sapiens (human) ]

    Gene ID: 4991, updated on 27-Nov-2024

    Summary

    Official Symbol
    OR1D2provided by HGNC
    Official Full Name
    olfactory receptor family 1 subfamily D member 2provided by HGNC
    Primary source
    HGNC:HGNC:8183
    See related
    Ensembl:ENSG00000184166 MIM:164342; AllianceGenome:HGNC:8183
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    OLFR1; OR17-4
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Orthologs
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    Genomic context

    See OR1D2 in Genome Data Viewer
    Location:
    17p13.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (3088484..3104422, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (2976732..2992671, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (2991778..3007716, complement)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene RAP1 GTPase activating protein 2 Neighboring gene uncharacterized LOC101927911 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:2868522-2869022 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:2869023-2869523 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:2898072-2898248 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:2898498-2898998 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11501 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11502 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11503 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:2914073-2914574 Neighboring gene olfactory receptor family 1 subfamily D member 5 Neighboring gene olfactory receptor family 1 subfamily E member 3 (gene/pseudogene) Neighboring gene olfactory receptor family 1 subfamily G member 1

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC119942, MGC119943

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables olfactory receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in chemotaxis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sensory perception of smell TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in single fertilization IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    olfactory receptor 1D2
    Names
    olfactory receptor 17-4
    olfactory receptor OR17-6
    olfactory receptor-like protein HGMP07E

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001386088.1NP_001373017.1  olfactory receptor 1D2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AC097370
      Consensus CDS
      CCDS11019.1
      UniProtKB/Swiss-Prot
      P34982, Q6IFL8, Q96RA4, Q9UM78
      UniProtKB/TrEMBL
      A0A126GVV4, A0A126GWN1, A0A126GWN6, A0A126GWN9, A0A126GWP7
      Related
      ENSP00000493077.1, ENST00000641064.1
      Conserved Domains (1) summary
      cd15918
      Location:25293
      7tmA_OR1_7-like; olfactory receptor families 1, 7, and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
    2. NM_002548.3NP_002539.2  olfactory receptor 1D2

      See identical proteins and their annotated locations for NP_002539.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AC097370
      Consensus CDS
      CCDS11019.1
      UniProtKB/Swiss-Prot
      P34982, Q6IFL8, Q96RA4, Q9UM78
      UniProtKB/TrEMBL
      A0A126GVV4, A0A126GWN1, A0A126GWN6, A0A126GWN9, A0A126GWP7
      Related
      ENSP00000493103.1, ENST00000641833.1
      Conserved Domains (1) summary
      cd15918
      Location:25293
      7tmA_OR1_7-like; olfactory receptor families 1, 7, and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

      Range
      3088484..3104422 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060941.1 Alternate T2T-CHM13v2.0

      Range
      2976732..2992671 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)