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    nic1 plasma membrane NiCoT heavy metal ion transmembrane transporter Nic1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539250, updated on 14-Nov-2024

    Summary

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    Official Symbol
    nic1
    Official Full Name
    plasma membrane NiCoT heavy metal ion transmembrane transporter Nic1
    Primary source
    PomBase:SPCC1884.02
    Locus tag
    SPOM_SPCC1884.02
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPCC757.01
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    Genomic context

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    See nic1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (43543..46985)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene epimarase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene glyoxylase III Hsp3101 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nic1p, a relative of bacterial transition metal permeases in Schizosaccharomyces pombe, provides nickel ion for urease biosynthesis. Eitinger T, et al. J Biol Chem, 2000 Jun 16. PMID 10748059
    2. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article
    3. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
    4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables high-affinity nickel cation transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables high-affinity nickel cation transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nickel cation import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nickel cation import across plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in plasma membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plasma membrane NiCoT heavy metal ion transmembrane transporter Nic1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      43543..46985
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022671.3 → NP_587676.3  plasma membrane NiCoT heavy metal ion transmembrane transporter Nic1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_587676.3

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74869, O74912
      Conserved Domains (1) summary
      COG3376
      Location:17 → 359
      HoxN; High-affinity nickel permease [Inorganic ion transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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