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    Ppil6 peptidylprolyl isomerase (cyclophilin)-like 6 [ Mus musculus (house mouse) ]

    Gene ID: 73075, updated on 10-Oct-2024

    Summary

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    Official Symbol
    Ppil6provided by MGI
    Official Full Name
    peptidylprolyl isomerase (cyclophilin)-like 6provided by MGI
    Primary source
    MGI:MGI:1920325
    See related
    Ensembl:ENSMUSG00000078451 AllianceGenome:MGI:1920325
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2900084F20Rik
    Summary
    Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding and protein peptidyl-prolyl isomerization. Predicted to be active in cytoplasm. Orthologous to human PPIL6 (peptidylprolyl isomerase like 6). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in testis adult (RPKM 8.2), bladder adult (RPKM 5.6) and 15 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ppil6 in Genome Data Viewer
    Location:
    10 B1- B2; 10 22.43 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (41366414..41390286)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (41490371..41514295)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:41197812-41197921 Neighboring gene predicted gene, 51797 Neighboring gene microtubule associated monooxygenase, calponin and LIM domain containing 1 Neighboring gene sphingomyelin phosphodiesterase 2, neutral Neighboring gene STARR-positive B cell enhancer ABC_E2932 Neighboring gene STARR-positive B cell enhancer ABC_E5127 Neighboring gene CD164 antigen Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:41272644-41272850 Neighboring gene coiled-coil domain containing 162 Neighboring gene predicted gene 17196

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Tissue expression patterns identify mouse cilia genes. McClintock TS, et al. Physiol Genomics, 2008 Jan 17. PMID 17971504
    2. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579
    3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables peptidyl-prolyl cis-trans isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein peptidyl-prolyl isomerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    probable inactive peptidyl-prolyl cis-trans isomerase-like 6
    Names
    PPIase
    cyclophilin-like protein PPIL6
    peptidyl-prolyl cis-trans isomerase-like 6
    problable inactive peptidyl-prolyl cis-trans isomerase-like 6
    rotamase PPIL6
    NP_001394931.1
    NP_001394932.1
    NP_001394933.1
    NP_001394934.1
    NP_001394935.1
    NP_001394936.1
    NP_082706.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001408002.1 → NP_001394931.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC153360

    2. NM_001408003.1 → NP_001394932.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC132290, AC153360

    3. NM_001408004.1 → NP_001394933.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC132290, AC153360

    4. NM_001408005.1 → NP_001394934.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC153360

    5. NM_001408006.1 → NP_001394935.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC132290, AC153360
      Related
      ENSMUSP00000149689.2, ENSMUST00000214145.2

    6. NM_001408007.1 → NP_001394936.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC132290, AC153360

    7. NM_028430.2 → NP_082706.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 1

      See identical proteins and their annotated locations for NP_082706.1

      Status: VALIDATED

      Source sequence(s)
      AC132290, AC153360
      Consensus CDS
      CCDS48548.1
      UniProtKB/Swiss-Prot
      B2RWF7, Q9D6D8
      Related
      ENSMUSP00000101146.4, ENSMUST00000105507.5
      Conserved Domains (1) summary
      cl00197
      Location:146 → 309
      cyclophilin; cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the ...

    RNA

    1. NR_176439.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC132290, AC153360

    2. NR_176440.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC132290, AC153360

    3. NR_176441.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC132290, AC153360

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      41366414..41390286
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_871442.4 RNA Sequence

    2. XR_380080.5 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D6D8.2 GenPept UniProtKB/Swiss-Prot:Q9D6D8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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