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    ADGRG1 adhesion G protein-coupled receptor G1 [ Homo sapiens (human) ]

    Gene ID: 9289, updated on 10-Dec-2024

    Summary

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    Official Symbol
    ADGRG1provided by HGNC
    Official Full Name
    adhesion G protein-coupled receptor G1provided by HGNC
    Primary source
    HGNC:HGNC:4512
    See related
    Ensembl:ENSG00000205336 MIM:604110; AllianceGenome:HGNC:4512
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    BFPP; BPPR; GPR56; TM7LN4; TM7XN1; CDCBM14B; CDCBM15A
    Summary
    This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
    Expression
    Broad expression in thyroid (RPKM 64.7), brain (RPKM 53.2) and 20 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See ADGRG1 in Genome Data Viewer
    Location:
    16q21
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (57619738..57665567)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (63414941..63460767)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (57653650..57699479)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371291 Neighboring gene uncharacterized LOC107984889 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10903 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10904 Neighboring gene high mobility group box 3 pseudogene 32 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10905 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10906 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:57653277-57653781 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:57653782-57654285 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:57654286-57654790 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:57656181-57657035 Neighboring gene Sharpr-MPRA regulatory region 10529 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:57661723-57662378 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:57662379-57663034 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:57665003-57665658 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:57685116-57685516 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:57692922-57693920 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:57693921-57694919 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:57710685-57711625 Neighboring gene adhesion G protein-coupled receptor G3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10907 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10908 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10909 Neighboring gene dynein regulatory complex subunit 7 Neighboring gene MTCH2 pseudogene 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. GPR56/ADGRG1 Inhibits Mesenchymal Differentiation and Radioresistance in Glioblastoma. Moreno M, et al. Cell Rep, 2017 Nov 21. PMID 29166609
    2. Specific and direct modulation of the interaction between adhesion GPCR GPR56/ADGRG1 and tissue transglutaminase 2 using synthetic ligands. Salzman GS, et al. Sci Rep, 2020 Oct 9. PMID 33037308, Free PMC Article
    3. Conventional magnetic resonance imaging and diffusion tensor imaging studies in children with novel GPR56 mutations: further delineation of a cobblestone-like phenotype. Quattrocchi CC, et al. Neurogenetics, 2013 Feb. PMID 23274687
    4. In Silico Approach in Designing a Novel Multi-Epitope Vaccine Candidate against Non-Small Cell Lung Cancer with Overexpressed G Protein-Coupled Receptor 56. Herrera LRM. Asian Pac J Cancer Prev, 2020 Aug 1. PMID 32856858, Free PMC Article
    5. Splicing variants of the orphan G-protein-coupled receptor GPR56 regulate the activity of transcription factors associated with tumorigenesis. Kim JE, et al. J Cancer Res Clin Oncol, 2010 Jan. PMID 19572147

    See all (99) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The G Protein-Coupled Receptor GPR56 Is an Inhibitory Checkpoint for NK Cell Migration.
      Title: The G Protein-Coupled Receptor GPR56 Is an Inhibitory Checkpoint for NK Cell Migration.
    2. Differential GPR56 Expression in T Cell Subpopulations for Early-Stage Lung Adenocarcinoma Patient Identification.
      Title: Differential GPR56 Expression in T Cell Subpopulations for Early-Stage Lung Adenocarcinoma Patient Identification.
    3. Expression of GPR56 reflects a hypoactivated state of circulating B cells and is downregulated in B cell subsets in patients with early-stage lung adenocarcinoma.
      Title: Expression of GPR56 reflects a hypoactivated state of circulating B cells and is downregulated in B cell subsets in patients with early-stage lung adenocarcinoma.
    4. GPR56 Promotes Diabetic Kidney Disease Through eNOS Regulation in Glomerular Endothelial Cells.
      Title: GPR56 Promotes Diabetic Kidney Disease Through eNOS Regulation in Glomerular Endothelial Cells.
    5. Downstream signalling of the disease-associated mutations on GPR56/ADGRG1.
      Title: Downstream signalling of the disease-associated mutations on GPR56/ADGRG1.
    6. Re-routing GPR56 signalling using Galpha12/13 G protein chimeras.
      Title: Re-routing GPR56 signalling using Gα(12/13) G protein chimeras.
    7. Cobblestone-like brain malformation with a new bi-allelic ADGRG1 (GPR-56) mutation: Fetal imaging-pathology correlation.
      Title: Cobblestone-like brain malformation with a new bi-allelic ADGRG1 (GPR-56) mutation: Fetal imaging-pathology correlation.
    8. Ablation of GPR56 Causes beta-Cell Dysfunction by ATP Loss through Mistargeting of Mitochondrial VDAC1 to the Plasma Membrane.
      Title: Ablation of GPR56 Causes β-Cell Dysfunction by ATP Loss through Mistargeting of Mitochondrial VDAC1 to the Plasma Membrane.
    9. Role of GPR56 in Platelet Activation and Arterial Thrombosis.
      Title: Role of GPR56 in Platelet Activation and Arterial Thrombosis.
    10. Single cell sequencing identifies clonally expanded synovial CD4(+) TPH cells expressing GPR56 in rheumatoid arthritis.
      Title: Single cell sequencing identifies clonally expanded synovial CD4(+) T(PH) cells expressing GPR56 in rheumatoid arthritis.
    Submit: New GeneRIF Correction See all GeneRIFs (71)

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Bilateral frontoparietal polymicrogyria
    MedGen: C1847352 OMIM: 606854 GeneReviews: Not available
    		Compare labs
    Polymicrogyria, bilateral perisylvian, autosomal recessive
    MedGen: C3810405 OMIM: 615752 GeneReviews: Not available
    		Compare labs

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • DKFZp781L1398

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables G protein-coupled receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables collagen binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables extracellular matrix binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables heparin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables heparin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in Rho protein signal transduction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in angiogenesis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in brain development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell adhesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in cell migration IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell-cell signaling TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in cerebral cortex radial glia-guided migration ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in cerebral cortex regionalization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in hematopoietic stem cell homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in layer formation in cerebral cortex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in negative regulation of cell population proliferation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of neuron migration ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in neural precursor cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of Rho protein signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of cell adhesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of neural precursor cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of vascular endothelial growth factor signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in seminiferous tubule development IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular exosome HDA PubMed 
    located_in glial limiting end-foot ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in membrane raft IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    adhesion G-protein coupled receptor G1
    Names
    7-transmembrane protein with no EGF-like N-terminal domains-1
    G protein-coupled receptor 56
    testicular tissue protein Li 77
    NP_001139242.1
    NP_001139243.1
    NP_001139244.1
    NP_001139245.1
    NP_001139246.1
    NP_001277071.1
    NP_001277072.1
    NP_001277073.1
    NP_001357357.1
    NP_001357358.1
    NP_001357359.1
    NP_001357360.1
    NP_001357361.1
    NP_001357362.1
    NP_001357363.1
    NP_001357364.1
    NP_001357365.1
    NP_001357366.1
    NP_001357367.1
    NP_001357368.1
    NP_001357369.1
    NP_001357370.1
    NP_001357371.1
    NP_001357380.1
    NP_001357382.1
    NP_001357383.1
    NP_005673.3
    NP_958932.1
    NP_958933.1
    XP_005256294.1
    XP_005256295.1
    XP_005256296.1
    XP_005256297.1
    XP_005256298.1
    XP_005256299.1
    XP_005256301.1
    XP_005256302.1
    XP_005256303.1
    XP_005256305.1
    XP_005256309.1
    XP_005256311.1
    XP_005256312.1
    XP_006721401.1
    XP_006721402.1
    XP_006721403.1
    XP_006721405.1
    XP_006721410.1
    XP_011521764.1
    XP_011521768.1
    XP_011521770.1
    XP_016879381.1
    XP_047290862.1
    XP_047290863.1
    XP_047290864.1
    XP_047290865.1
    XP_047290866.1
    XP_047290867.1
    XP_047290868.1
    XP_047290869.1
    XP_047290870.1
    XP_047290871.1
    XP_047290872.1
    XP_054170357.1
    XP_054170358.1
    XP_054170359.1
    XP_054170360.1
    XP_054170361.1
    XP_054170362.1
    XP_054170363.1
    XP_054170364.1
    XP_054170365.1
    XP_054170366.1
    XP_054170367.1
    XP_054170368.1
    XP_054170369.1
    XP_054170370.1
    XP_054170371.1
    XP_054170372.1
    XP_054170373.1
    XP_054170374.1
    XP_054170375.1
    XP_054170376.1
    XP_054170377.1
    XP_054170378.1
    XP_054170379.1
    XP_054170380.1
    XP_054170381.1
    XP_054170382.1
    XP_054170383.1
    XP_054170384.1
    XP_054170385.1
    XP_054170386.1
    XP_054170387.1
    XP_054170388.1
    XP_054170389.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_011643.1 RefSeqGene

      Range
      13633..50570
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001145770.3 → NP_001139242.1  adhesion G-protein coupled receptor G1 isoform b precursor

      See identical proteins and their annotated locations for NP_001139242.1

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32461.1
      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7
      Related
      ENSP00000457456.1, ENST00000568908.5
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 668
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    2. NM_001145771.3 → NP_001139243.1  adhesion G-protein coupled receptor G1 isoform a precursor

      See identical proteins and their annotated locations for NP_001139243.1

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32460.1
      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 674
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    3. NM_001145772.3 → NP_001139244.1  adhesion G-protein coupled receptor G1 isoform b precursor

      See identical proteins and their annotated locations for NP_001139244.1

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32461.1
      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7
      Related
      ENSP00000373465.5, ENST00000388813.9
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 668
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    4. NM_001145773.3 → NP_001139245.1  adhesion G-protein coupled receptor G1 isoform c precursor

      See identical proteins and their annotated locations for NP_001139245.1

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS73893.1
      UniProtKB/TrEMBL
      B3KQN7
      Related
      ENSP00000398034.2, ENST00000456916.5
      Conserved Domains (5) summary
      cd14964
      Location:408 → 432
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:350 → 393
      GPS; GPCR proteolysis site, GPS, motif
      pfam18587
      Location:34 → 167
      PLL; PTX/LNS-Like (PLL) domain
      pfam18619
      Location:178 → 225
      GAIN_A; GPCR-Autoproteolysis-INducing (GAIN) subdomain A
      cl28897
      Location:405 → 673
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    5. NM_001145774.3 → NP_001139246.1  adhesion G-protein coupled receptor G1 isoform b precursor

      See identical proteins and their annotated locations for NP_001139246.1

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32461.1
      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7
      Related
      ENSP00000444911.2, ENST00000540164.6
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 668
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    6. NM_001290142.2 → NP_001277071.1  adhesion G-protein coupled receptor G1 isoform d precursor

      Status: REVIEWED

      Source sequence(s)
      AC018552
      UniProtKB/TrEMBL
      B4DM06
      Conserved Domains (2) summary
      pfam01825
      Location:174 → 218
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:233 → 484
      7tm_4; Olfactory receptor

    7. NM_001290143.2 → NP_001277072.1  adhesion G-protein coupled receptor G1 isoform e

      Status: REVIEWED

      Source sequence(s)
      AC018552
      UniProtKB/TrEMBL
      B4DM06
      Conserved Domains (2) summary
      pfam01825
      Location:169 → 213
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:228 → 479
      7tm_4; Olfactory receptor

    8. NM_001290144.2 → NP_001277073.1  adhesion G-protein coupled receptor G1 isoform f

      Status: REVIEWED

      Source sequence(s)
      AC018552
      UniProtKB/TrEMBL
      B4DM06
      Conserved Domains (3) summary
      pfam01825
      Location:170 → 213
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:228 → 252
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:225 → 493
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    9. NM_001370428.1 → NP_001357357.1  adhesion G-protein coupled receptor G1 isoform a precursor

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32460.1
      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 674
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    10. NM_001370429.1 → NP_001357358.1  adhesion G-protein coupled receptor G1 isoform a precursor

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32460.1
      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94
      Related
      ENSP00000500185.2, ENST00000673126.2
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 674
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    11. NM_001370430.1 → NP_001357359.1  adhesion G-protein coupled receptor G1 isoform a precursor

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32460.1
      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 674
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    12. NM_001370431.1 → NP_001357360.1  adhesion G-protein coupled receptor G1 isoform a precursor

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32460.1
      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 674
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    13. NM_001370432.1 → NP_001357361.1  adhesion G-protein coupled receptor G1 isoform a precursor

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32460.1
      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94
      Related
      ENSP00000455215.1, ENST00000568909.5
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 674
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    14. NM_001370433.1 → NP_001357362.1  adhesion G-protein coupled receptor G1 isoform c precursor

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS73893.1
      UniProtKB/TrEMBL
      B3KQN7
      Conserved Domains (5) summary
      cd14964
      Location:408 → 432
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:350 → 393
      GPS; GPCR proteolysis site, GPS, motif
      pfam18587
      Location:34 → 167
      PLL; PTX/LNS-Like (PLL) domain
      pfam18619
      Location:178 → 225
      GAIN_A; GPCR-Autoproteolysis-INducing (GAIN) subdomain A
      cl28897
      Location:405 → 673
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    15. NM_001370434.1 → NP_001357363.1  adhesion G-protein coupled receptor G1 isoform i precursor

      Status: REVIEWED

      Source sequence(s)
      AC018552
      UniProtKB/TrEMBL
      A0A5F9ZH94
      Conserved Domains (5) summary
      cd14964
      Location:401 → 426
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:344 → 387
      GPS; GPCR proteolysis site, GPS, motif
      pfam18587
      Location:29 → 162
      PLL; PTX/LNS-Like (PLL) domain
      pfam18619
      Location:173 → 220
      GAIN_A; GPCR-Autoproteolysis-INducing (GAIN) subdomain A
      cl28897
      Location:399 → 673
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    16. NM_001370435.1 → NP_001357364.1  adhesion G-protein coupled receptor G1 isoform b precursor

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32461.1
      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 668
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    17. NM_001370436.1 → NP_001357365.1  adhesion G-protein coupled receptor G1 isoform b precursor

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32461.1
      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 668
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    18. NM_001370437.1 → NP_001357366.1  adhesion G-protein coupled receptor G1 isoform b precursor

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32461.1
      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 668
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    19. NM_001370438.1 → NP_001357367.1  adhesion G-protein coupled receptor G1 isoform b precursor

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32461.1
      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 668
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    20. NM_001370439.1 → NP_001357368.1  adhesion G-protein coupled receptor G1 isoform b precursor

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32461.1
      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 668
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    21. NM_001370440.1 → NP_001357369.1  adhesion G-protein coupled receptor G1 isoform b precursor

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32461.1
      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 668
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    22. NM_001370441.1 → NP_001357370.1  adhesion G-protein coupled receptor G1 isoform g precursor

      Status: REVIEWED

      Source sequence(s)
      AC018552
      UniProtKB/TrEMBL
      B3KQN7
      Conserved Domains (3) summary
      pfam01825
      Location:344 → 387
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:402 → 426
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:399 → 667
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    23. NM_001370442.1 → NP_001357371.1  adhesion G-protein coupled receptor G1 isoform h precursor

      Status: REVIEWED

      Source sequence(s)
      AC018552
      UniProtKB/TrEMBL
      B3KQN7
      Conserved Domains (3) summary
      pfam01825
      Location:293 → 336
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:351 → 375
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:348 → 616
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    24. NM_001370451.1 → NP_001357380.1  adhesion G-protein coupled receptor G1 isoform f

      Status: REVIEWED

      Source sequence(s)
      AC018552
      UniProtKB/TrEMBL
      B4DM06
      Conserved Domains (3) summary
      pfam01825
      Location:170 → 213
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:228 → 252
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:225 → 493
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    25. NM_001370453.1 → NP_001357382.1  adhesion G-protein coupled receptor G1 isoform f

      Status: REVIEWED

      Source sequence(s)
      AC018552
      UniProtKB/TrEMBL
      B4DM06
      Conserved Domains (3) summary
      pfam01825
      Location:170 → 213
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:228 → 252
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:225 → 493
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    26. NM_001370454.1 → NP_001357383.1  adhesion G-protein coupled receptor G1 isoform f

      Status: REVIEWED

      Source sequence(s)
      AC018552
      UniProtKB/TrEMBL
      B4DM06
      Conserved Domains (3) summary
      pfam01825
      Location:170 → 213
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:228 → 252
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:225 → 493
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    27. NM_005682.7 → NP_005673.3  adhesion G-protein coupled receptor G1 isoform a precursor

      See identical proteins and their annotated locations for NP_005673.3

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32460.1
      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94
      Related
      ENSP00000456794.1, ENST00000567835.5
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 674
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    28. NM_201524.4 → NP_958932.1  adhesion G-protein coupled receptor G1 isoform b precursor

      See identical proteins and their annotated locations for NP_958932.1

      Status: REVIEWED

      Source sequence(s)
      AC018552
      Consensus CDS
      CCDS32461.1
      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7
      Related
      ENSP00000456620.1, ENST00000562558.6
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 668
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    29. NM_201525.4 → NP_958933.1  adhesion G-protein coupled receptor G1 isoform b precursor

      See identical proteins and their annotated locations for NP_958933.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice site in the coding region compared to variant 4. The resulting isoform (b, also known as S1) is shorter than isoform a. Variants 2, 3, 5, 6, and 7 encode the same isoform.
      Source sequence(s)
      AC018552, AK075555, AK299110, AK312405, CR936747
      Consensus CDS
      CCDS32461.1
      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7
      Related
      ENSP00000455351.2, ENST00000562631.7
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 668
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      57619738..57665567
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006721340.4 → XP_006721403.1  adhesion G-protein coupled receptor G1 isoform X1

      See identical proteins and their annotated locations for XP_006721403.1

      UniProtKB/TrEMBL
      A0A5F9ZH94
      Conserved Domains (2) summary
      pfam01825
      Location:349 → 393
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:408 → 659
      7tm_4; Olfactory receptor

    2. XM_047434907.1 → XP_047290863.1  adhesion G-protein coupled receptor G1 isoform X3

      UniProtKB/TrEMBL
      B3KQN7
      Conserved Domains (5) summary
      cd14964
      Location:408 → 432
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:350 → 393
      GPS; GPCR proteolysis site, GPS, motif
      pfam18587
      Location:34 → 167
      PLL; PTX/LNS-Like (PLL) domain
      pfam18619
      Location:178 → 225
      GAIN_A; GPCR-Autoproteolysis-INducing (GAIN) subdomain A
      cl28897
      Location:405 → 673
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    3. XM_005256242.5 → XP_005256299.1  adhesion G-protein coupled receptor G1 isoform X1

      See identical proteins and their annotated locations for XP_005256299.1

      UniProtKB/TrEMBL
      A0A5F9ZH94
      Conserved Domains (2) summary
      pfam01825
      Location:349 → 393
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:408 → 659
      7tm_4; Olfactory receptor

    4. XM_047434912.1 → XP_047290868.1  adhesion G-protein coupled receptor G1 isoform X3

      UniProtKB/TrEMBL
      B3KQN7
      Conserved Domains (5) summary
      cd14964
      Location:408 → 432
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:350 → 393
      GPS; GPCR proteolysis site, GPS, motif
      pfam18587
      Location:34 → 167
      PLL; PTX/LNS-Like (PLL) domain
      pfam18619
      Location:178 → 225
      GAIN_A; GPCR-Autoproteolysis-INducing (GAIN) subdomain A
      cl28897
      Location:405 → 673
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    5. XM_047434906.1 → XP_047290862.1  adhesion G-protein coupled receptor G1 isoform X1

      UniProtKB/TrEMBL
      A0A5F9ZH94

    6. XM_047434910.1 → XP_047290866.1  adhesion G-protein coupled receptor G1 isoform X3

      UniProtKB/TrEMBL
      B3KQN7
      Conserved Domains (5) summary
      cd14964
      Location:408 → 432
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:350 → 393
      GPS; GPCR proteolysis site, GPS, motif
      pfam18587
      Location:34 → 167
      PLL; PTX/LNS-Like (PLL) domain
      pfam18619
      Location:178 → 225
      GAIN_A; GPCR-Autoproteolysis-INducing (GAIN) subdomain A
      cl28897
      Location:405 → 673
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    7. XM_006721339.5 → XP_006721402.1  adhesion G-protein coupled receptor G1 isoform X1

      See identical proteins and their annotated locations for XP_006721402.1

      UniProtKB/TrEMBL
      A0A5F9ZH94
      Conserved Domains (2) summary
      pfam01825
      Location:349 → 393
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:408 → 659
      7tm_4; Olfactory receptor

    8. XM_047434908.1 → XP_047290864.1  adhesion G-protein coupled receptor G1 isoform X3

      UniProtKB/TrEMBL
      B3KQN7
      Conserved Domains (5) summary
      cd14964
      Location:408 → 432
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:350 → 393
      GPS; GPCR proteolysis site, GPS, motif
      pfam18587
      Location:34 → 167
      PLL; PTX/LNS-Like (PLL) domain
      pfam18619
      Location:178 → 225
      GAIN_A; GPCR-Autoproteolysis-INducing (GAIN) subdomain A
      cl28897
      Location:405 → 673
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    9. XM_005256240.5 → XP_005256297.1  adhesion G-protein coupled receptor G1 isoform X1

      See identical proteins and their annotated locations for XP_005256297.1

      UniProtKB/TrEMBL
      A0A5F9ZH94
      Conserved Domains (2) summary
      pfam01825
      Location:349 → 393
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:408 → 659
      7tm_4; Olfactory receptor

    10. XM_005256245.3 → XP_005256302.1  adhesion G-protein coupled receptor G1 isoform X1

      See identical proteins and their annotated locations for XP_005256302.1

      UniProtKB/TrEMBL
      A0A5F9ZH94
      Conserved Domains (2) summary
      pfam01825
      Location:349 → 393
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:408 → 659
      7tm_4; Olfactory receptor

    11. XM_005256254.3 → XP_005256311.1  adhesion G-protein coupled receptor G1 isoform X2

      See identical proteins and their annotated locations for XP_005256311.1

      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 674
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    12. XM_017023892.2 → XP_016879381.1  adhesion G-protein coupled receptor G1 isoform X4

      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7
      Related
      ENSP00000500676.1, ENST00000672974.1
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 668
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    13. XM_006721338.3 → XP_006721401.1  adhesion G-protein coupled receptor G1 isoform X1

      See identical proteins and their annotated locations for XP_006721401.1

      UniProtKB/TrEMBL
      A0A5F9ZH94
      Conserved Domains (2) summary
      pfam01825
      Location:349 → 393
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:408 → 659
      7tm_4; Olfactory receptor

    14. XM_047434911.1 → XP_047290867.1  adhesion G-protein coupled receptor G1 isoform X3

      UniProtKB/TrEMBL
      B3KQN7
      Conserved Domains (5) summary
      cd14964
      Location:408 → 432
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:350 → 393
      GPS; GPCR proteolysis site, GPS, motif
      pfam18587
      Location:34 → 167
      PLL; PTX/LNS-Like (PLL) domain
      pfam18619
      Location:178 → 225
      GAIN_A; GPCR-Autoproteolysis-INducing (GAIN) subdomain A
      cl28897
      Location:405 → 673
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    15. XM_006721342.3 → XP_006721405.1  adhesion G-protein coupled receptor G1 isoform X2

      See identical proteins and their annotated locations for XP_006721405.1

      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 674
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    16. XM_005256238.3 → XP_005256295.1  adhesion G-protein coupled receptor G1 isoform X1

      See identical proteins and their annotated locations for XP_005256295.1

      UniProtKB/TrEMBL
      A0A5F9ZH94
      Conserved Domains (2) summary
      pfam01825
      Location:349 → 393
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:408 → 659
      7tm_4; Olfactory receptor

    17. XM_006721347.3 → XP_006721410.1  adhesion G-protein coupled receptor G1 isoform X3

      See identical proteins and their annotated locations for XP_006721410.1

      UniProtKB/TrEMBL
      B3KQN7
      Conserved Domains (5) summary
      cd14964
      Location:408 → 432
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:350 → 393
      GPS; GPCR proteolysis site, GPS, motif
      pfam18587
      Location:34 → 167
      PLL; PTX/LNS-Like (PLL) domain
      pfam18619
      Location:178 → 225
      GAIN_A; GPCR-Autoproteolysis-INducing (GAIN) subdomain A
      cl28897
      Location:405 → 673
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    18. XM_005256255.3 → XP_005256312.1  adhesion G-protein coupled receptor G1 isoform X4

      See identical proteins and their annotated locations for XP_005256312.1

      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 668
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    19. XM_005256237.3 → XP_005256294.1  adhesion G-protein coupled receptor G1 isoform X1

      See identical proteins and their annotated locations for XP_005256294.1

      UniProtKB/TrEMBL
      A0A5F9ZH94
      Conserved Domains (2) summary
      pfam01825
      Location:349 → 393
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:408 → 659
      7tm_4; Olfactory receptor

    20. XM_005256239.3 → XP_005256296.1  adhesion G-protein coupled receptor G1 isoform X1

      See identical proteins and their annotated locations for XP_005256296.1

      UniProtKB/TrEMBL
      A0A5F9ZH94
      Conserved Domains (2) summary
      pfam01825
      Location:349 → 393
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:408 → 659
      7tm_4; Olfactory receptor

    21. XM_047434909.1 → XP_047290865.1  adhesion G-protein coupled receptor G1 isoform X3

      UniProtKB/TrEMBL
      B3KQN7
      Conserved Domains (5) summary
      cd14964
      Location:408 → 432
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam01825
      Location:350 → 393
      GPS; GPCR proteolysis site, GPS, motif
      pfam18587
      Location:34 → 167
      PLL; PTX/LNS-Like (PLL) domain
      pfam18619
      Location:178 → 225
      GAIN_A; GPCR-Autoproteolysis-INducing (GAIN) subdomain A
      cl28897
      Location:405 → 673
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    22. XM_005256246.3 → XP_005256303.1  adhesion G-protein coupled receptor G1 isoform X2

      See identical proteins and their annotated locations for XP_005256303.1

      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 674
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    23. XM_005256244.4 → XP_005256301.1  adhesion G-protein coupled receptor G1 isoform X1

      See identical proteins and their annotated locations for XP_005256301.1

      UniProtKB/TrEMBL
      A0A5F9ZH94
      Conserved Domains (2) summary
      pfam01825
      Location:349 → 393
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:408 → 659
      7tm_4; Olfactory receptor

    24. XM_005256248.3 → XP_005256305.1  adhesion G-protein coupled receptor G1 isoform X2

      See identical proteins and their annotated locations for XP_005256305.1

      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94
      Related
      ENSP00000454933.2, ENST00000565976.6
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 674
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    25. XM_047434914.1 → XP_047290870.1  adhesion G-protein coupled receptor G1 isoform X4

      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7

    26. XM_011523462.3 → XP_011521764.1  adhesion G-protein coupled receptor G1 isoform X1

      See identical proteins and their annotated locations for XP_011521764.1

      UniProtKB/TrEMBL
      A0A5F9ZH94
      Conserved Domains (2) summary
      pfam01825
      Location:349 → 393
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:408 → 659
      7tm_4; Olfactory receptor

    27. XM_011523466.3 → XP_011521768.1  adhesion G-protein coupled receptor G1 isoform X2

      See identical proteins and their annotated locations for XP_011521768.1

      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 674
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    28. XM_047434913.1 → XP_047290869.1  adhesion G-protein coupled receptor G1 isoform X4

      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7

    29. XM_011523468.3 → XP_011521770.1  adhesion G-protein coupled receptor G1 isoform X2

      See identical proteins and their annotated locations for XP_011521770.1

      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 674
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    30. XM_047434916.1 → XP_047290872.1  adhesion G-protein coupled receptor G1 isoform X4

      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7

    31. XM_005256241.5 → XP_005256298.1  adhesion G-protein coupled receptor G1 isoform X1

      See identical proteins and their annotated locations for XP_005256298.1

      UniProtKB/TrEMBL
      A0A5F9ZH94
      Conserved Domains (2) summary
      pfam01825
      Location:349 → 393
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:408 → 659
      7tm_4; Olfactory receptor

    32. XM_005256252.3 → XP_005256309.1  adhesion G-protein coupled receptor G1 isoform X2

      See identical proteins and their annotated locations for XP_005256309.1

      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94
      Conserved Domains (3) summary
      pfam01825
      Location:345 → 388
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:403 → 427
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:400 → 674
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    33. XM_047434915.1 → XP_047290871.1  adhesion G-protein coupled receptor G1 isoform X4

      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      63414941..63460767
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054314384.1 → XP_054170359.1  adhesion G-protein coupled receptor G1 isoform X1

      UniProtKB/TrEMBL
      A0A5F9ZH94

    2. XM_054314403.1 → XP_054170378.1  adhesion G-protein coupled receptor G1 isoform X3

      UniProtKB/TrEMBL
      B3KQN7

    3. XM_054314390.1 → XP_054170365.1  adhesion G-protein coupled receptor G1 isoform X1

      UniProtKB/TrEMBL
      A0A5F9ZH94

    4. XM_054314408.1 → XP_054170383.1  adhesion G-protein coupled receptor G1 isoform X3

      UniProtKB/TrEMBL
      B3KQN7

    5. XM_054314386.1 → XP_054170361.1  adhesion G-protein coupled receptor G1 isoform X1

      UniProtKB/TrEMBL
      A0A5F9ZH94

    6. XM_054314406.1 → XP_054170381.1  adhesion G-protein coupled receptor G1 isoform X3

      UniProtKB/TrEMBL
      B3KQN7

    7. XM_054314383.1 → XP_054170358.1  adhesion G-protein coupled receptor G1 isoform X1

      UniProtKB/TrEMBL
      A0A5F9ZH94

    8. XM_054314404.1 → XP_054170379.1  adhesion G-protein coupled receptor G1 isoform X3

      UniProtKB/TrEMBL
      B3KQN7

    9. XM_054314387.1 → XP_054170362.1  adhesion G-protein coupled receptor G1 isoform X1

      UniProtKB/TrEMBL
      A0A5F9ZH94

    10. XM_054314394.1 → XP_054170369.1  adhesion G-protein coupled receptor G1 isoform X1

      UniProtKB/TrEMBL
      A0A5F9ZH94

    11. XM_054314398.1 → XP_054170373.1  adhesion G-protein coupled receptor G1 isoform X2

      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94

    12. XM_054314412.1 → XP_054170387.1  adhesion G-protein coupled receptor G1 isoform X4

      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7

    13. XM_054314385.1 → XP_054170360.1  adhesion G-protein coupled receptor G1 isoform X1

      UniProtKB/TrEMBL
      A0A5F9ZH94

    14. XM_054314407.1 → XP_054170382.1  adhesion G-protein coupled receptor G1 isoform X3

      UniProtKB/TrEMBL
      B3KQN7

    15. XM_054314395.1 → XP_054170370.1  adhesion G-protein coupled receptor G1 isoform X2

      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94

    16. XM_054314382.1 → XP_054170357.1  adhesion G-protein coupled receptor G1 isoform X1

      UniProtKB/TrEMBL
      A0A5F9ZH94

    17. XM_054314402.1 → XP_054170377.1  adhesion G-protein coupled receptor G1 isoform X3

      UniProtKB/TrEMBL
      B3KQN7

    18. XM_054314409.1 → XP_054170384.1  adhesion G-protein coupled receptor G1 isoform X4

      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7

    19. XM_054314388.1 → XP_054170363.1  adhesion G-protein coupled receptor G1 isoform X1

      UniProtKB/TrEMBL
      A0A5F9ZH94

    20. XM_054314391.1 → XP_054170366.1  adhesion G-protein coupled receptor G1 isoform X1

      UniProtKB/TrEMBL
      A0A5F9ZH94

    21. XM_054314405.1 → XP_054170380.1  adhesion G-protein coupled receptor G1 isoform X3

      UniProtKB/TrEMBL
      B3KQN7

    22. XM_054314396.1 → XP_054170371.1  adhesion G-protein coupled receptor G1 isoform X2

      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94

    23. XM_054314392.1 → XP_054170367.1  adhesion G-protein coupled receptor G1 isoform X1

      UniProtKB/TrEMBL
      A0A5F9ZH94

    24. XM_054314399.1 → XP_054170374.1  adhesion G-protein coupled receptor G1 isoform X2

      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94

    25. XM_054314411.1 → XP_054170386.1  adhesion G-protein coupled receptor G1 isoform X4

      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7

    26. XM_054314397.1 → XP_054170372.1  adhesion G-protein coupled receptor G1 isoform X2

      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94

    27. XM_054314410.1 → XP_054170385.1  adhesion G-protein coupled receptor G1 isoform X4

      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7

    28. XM_054314401.1 → XP_054170376.1  adhesion G-protein coupled receptor G1 isoform X2

      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94

    29. XM_054314414.1 → XP_054170389.1  adhesion G-protein coupled receptor G1 isoform X4

      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7

    30. XM_054314389.1 → XP_054170364.1  adhesion G-protein coupled receptor G1 isoform X1

      UniProtKB/TrEMBL
      A0A5F9ZH94

    31. XM_054314400.1 → XP_054170375.1  adhesion G-protein coupled receptor G1 isoform X2

      UniProtKB/Swiss-Prot
      A6NIT7, A6NJV9, B0M0K4, B4DR54, O95966, Q6ZMP1, Q8NGB3, Q96HB4, Q9Y653
      UniProtKB/TrEMBL
      A0A024R6U7, A0A5F9ZH94

    32. XM_054314413.1 → XP_054170388.1  adhesion G-protein coupled receptor G1 isoform X4

      UniProtKB/TrEMBL
      A0A0S2Z517, B3KQN7

    33. XM_054314393.1 → XP_054170368.1  adhesion G-protein coupled receptor G1 isoform X1

      UniProtKB/TrEMBL
      A0A5F9ZH94
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9Y653.2 GenPept UniProtKB/Swiss-Prot:Q9Y653

    Gene LinkOut

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