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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001319179.2 → NP_001306108.1 guanylate-binding protein 3 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) contains an alternate exon compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
- Source sequence(s)
-
AK001823, AK309096, AL160008, BC144650, BP281050, CA450307
- Conserved Domains (3) summary
-
- pfam02841
Location:203 → 495
- GBP_C; Guanylate-binding protein, C-terminal domain
- cd16269
Location:209 → 495
- GBP_C; Guanylate-binding protein, C-terminal domain
- cl21455
Location:1 → 201
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
NM_001319180.2 → NP_001306109.1 guanylate-binding protein 3 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate splice junction compared to variant 1. The resulting isoform (3) has a shorter and distinct N-terminus compared to isoform 1.
- Source sequence(s)
-
AK001823, AK309096, AL160008, BP281050, CA450307
- Conserved Domains (3) summary
-
- pfam02841
Location:148 → 440
- GBP_C; Guanylate-binding protein, C-terminal domain
- cd16269
Location:154 → 440
- GBP_C; Guanylate-binding protein, C-terminal domain
- cl21455
Location:10 → 146
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
NM_001319181.2 → NP_001306110.1 guanylate-binding protein 3 isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) uses an alternate in-frame splice junction and differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (4) lacks an alternate internal segment and has a shorter and distinct C-terminus compared to isoform 1.
- Source sequence(s)
-
AL160008, BP281050, JF927951
- UniProtKB/TrEMBL
-
Q5D1D5
- Conserved Domains (3) summary
-
- pfam02841
Location:282 → 529
- GBP_C; Guanylate-binding protein, C-terminal domain
- pfam02263
Location:18 → 280
- GBP; Guanylate-binding protein, N-terminal domain
- cd16269
Location:288 → 529
- GBP_C; Guanylate-binding protein, C-terminal domain
-
NM_018284.3 → NP_060754.2 guanylate-binding protein 3 isoform 1
See identical proteins and their annotated locations for NP_060754.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
AL160008, CR936755, CR936758
- Consensus CDS
-
CCDS717.2
- UniProtKB/Swiss-Prot
- A2A317, A6NF86, B2RTW0, F8UW81, Q05D54, Q5T8L8, Q5T8L9, Q6P3V3, Q9H0R5, Q9NV33
- UniProtKB/TrEMBL
-
Q5D1D5
- Related
- ENSP00000359512.4, ENST00000370481.9
- Conserved Domains (3) summary
-
- pfam02841
Location:282 → 574
- GBP_C; Guanylate-binding protein, C-terminal domain
- pfam02263
Location:18 → 280
- GBP; Guanylate-binding protein, N-terminal domain
- cd16269
Location:288 → 574
- GBP_C; Guanylate-binding protein, C-terminal domain
RNA
-
NR_135007.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks two alternate exons compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AK001823, AK309096, BC063819, BP281050, CA450307
- Related
-
ENST00000489444.6
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000001.11 Reference GRCh38.p14 Primary Assembly
- Range
-
89006680..89022866 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011541233.2 → XP_011539535.1 guanylate-binding protein 3 isoform X2
See identical proteins and their annotated locations for XP_011539535.1
- Conserved Domains (3) summary
-
- pfam02841
Location:203 → 495
- GBP_C; Guanylate-binding protein, C-terminal domain
- cd16269
Location:209 → 495
- GBP_C; Guanylate-binding protein, C-terminal domain
- cl21455
Location:1 → 201
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
XM_011541234.3 → XP_011539536.1 guanylate-binding protein 3 isoform X3
- Conserved Domains (3) summary
-
- pfam02841
Location:210 → 493
- GBP_C; Guanylate-binding protein, C-terminal domain
- cd16269
Location:210 → 493
- GBP_C; Guanylate-binding protein, C-terminal domain
- cl21455
Location:18 → 209
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
XM_006710574.4 → XP_006710637.1 guanylate-binding protein 3 isoform X1
- UniProtKB/TrEMBL
-
Q5D1D5
- Related
- ENSP00000520850.1, ENST00000850557.1
- Conserved Domains (2) summary
-
- cd16269
Location:288 → 547
- GBP_C; Guanylate-binding protein, C-terminal domain
- pfam02263
Location:18 → 280
- GBP; Guanylate-binding protein, N-terminal domain
Alternate T2T-CHM13v2.0
Genomic
-
NC_060925.1 Alternate T2T-CHM13v2.0
- Range
-
88850078..88866271 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054335965.1 → XP_054191940.1 guanylate-binding protein 3 isoform X2
-
XM_054335966.1 → XP_054191941.1 guanylate-binding protein 3 isoform X3
-
XM_054335964.1 → XP_054191939.1 guanylate-binding protein 3 isoform X1
- UniProtKB/TrEMBL
-
Q5D1D5