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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001142497.3 → NP_001135969.1 mixed lineage kinase domain-like protein isoform 2
See identical proteins and their annotated locations for NP_001135969.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2, also known as MLKLshRNA-B) lacks several consecutive exons in the mid region and uses an alternate donor splice site at the next exon, which causes a localized frameshift compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter, lacking an internal protein segment compared to isoform 1.
- Source sequence(s)
-
BC028141, BQ575071, DB291522
- Consensus CDS
-
CCDS45528.1
- UniProtKB/Swiss-Prot
-
Q8NB16
- Related
- ENSP00000303118.7, ENST00000306247.11
- Conserved Domains (1) summary
-
- PHA02988
Location:212 → 261
- PHA02988; hypothetical protein; Provisional
-
NM_152649.4 → NP_689862.1 mixed lineage kinase domain-like protein isoform 1
See identical proteins and their annotated locations for NP_689862.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1, also known as MLKLshRNA-A) represents the longer transcript and encodes the longer isoform (1).
- Source sequence(s)
-
AK091708, BC028141, BQ575071
- Consensus CDS
-
CCDS32487.1
- UniProtKB/Swiss-Prot
- A6NCE4, Q8N6V0, Q8NB16
- UniProtKB/TrEMBL
-
Q5JPC5
- Related
- ENSP00000308351.7, ENST00000308807.12
- Conserved Domains (2) summary
-
- PHA02988
Location:177 → 469
- PHA02988; hypothetical protein; Provisional
- cl21453
Location:215 → 466
- PKc_like; Protein Kinases, catalytic domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000016.10 Reference GRCh38.p14 Primary Assembly
- Range
-
74671855..74700862 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_005255834.5 → XP_005255891.1 mixed lineage kinase domain-like protein isoform X1
See identical proteins and their annotated locations for XP_005255891.1
- UniProtKB/Swiss-Prot
- A6NCE4, Q8N6V0, Q8NB16
- UniProtKB/TrEMBL
-
Q5JPC5
- Conserved Domains (2) summary
-
- PHA02988
Location:177 → 469
- PHA02988; hypothetical protein; Provisional
- cl21453
Location:215 → 466
- PKc_like; Protein Kinases, catalytic domain
-
XM_047433704.1 → XP_047289660.1 mixed lineage kinase domain-like protein isoform X2
- UniProtKB/TrEMBL
-
Q5JPC5
-
XM_047433710.1 → XP_047289666.1 mixed lineage kinase domain-like protein isoform X8
-
XM_047433707.1 → XP_047289663.1 mixed lineage kinase domain-like protein isoform X5
-
XM_047433705.1 → XP_047289661.1 mixed lineage kinase domain-like protein isoform X3
-
XM_047433708.1 → XP_047289664.1 mixed lineage kinase domain-like protein isoform X6
-
XM_047433709.1 → XP_047289665.1 mixed lineage kinase domain-like protein isoform X7
-
XM_047433706.1 → XP_047289662.1 mixed lineage kinase domain-like protein isoform X4
- UniProtKB/TrEMBL
-
Q5JPC5
-
XM_011522936.3 → XP_011521238.1 mixed lineage kinase domain-like protein isoform X7
See identical proteins and their annotated locations for XP_011521238.1
- Conserved Domains (1) summary
-
- cl21453
Location:215 → 277
- PKc_like; Protein Kinases, catalytic domain
Alternate T2T-CHM13v2.0
Genomic
-
NC_060940.1 Alternate T2T-CHM13v2.0
- Range
-
80718597..80747927 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054379744.1 → XP_054235719.1 mixed lineage kinase domain-like protein isoform X1
- UniProtKB/Swiss-Prot
- A6NCE4, Q8N6V0, Q8NB16
- UniProtKB/TrEMBL
-
Q5JPC5
-
XM_054379745.1 → XP_054235720.1 mixed lineage kinase domain-like protein isoform X2
- UniProtKB/TrEMBL
-
Q5JPC5
-
XM_054379752.1 → XP_054235727.1 mixed lineage kinase domain-like protein isoform X8
-
XM_054379748.1 → XP_054235723.1 mixed lineage kinase domain-like protein isoform X5
-
XM_054379746.1 → XP_054235721.1 mixed lineage kinase domain-like protein isoform X3
-
XM_054379749.1 → XP_054235724.1 mixed lineage kinase domain-like protein isoform X6
-
XM_054379750.1 → XP_054235725.1 mixed lineage kinase domain-like protein isoform X7
-
XM_054379747.1 → XP_054235722.1 mixed lineage kinase domain-like protein isoform X4
- UniProtKB/TrEMBL
-
Q5JPC5
-
XM_054379751.1 → XP_054235726.1 mixed lineage kinase domain-like protein isoform X7