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    OR5C1 olfactory receptor family 5 subfamily C member 1 [ Homo sapiens (human) ]

    Gene ID: 392391, updated on 27-Nov-2024

    Summary

    Official Symbol
    OR5C1provided by HGNC
    Official Full Name
    olfactory receptor family 5 subfamily C member 1provided by HGNC
    Primary source
    HGNC:HGNC:8331
    See related
    Ensembl:ENSG00000148215 AllianceGenome:HGNC:8331
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    OR9-F; OR5C2P; OR9-31
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Orthologs
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    Genomic context

    See OR5C1 in Genome Data Viewer
    Location:
    9q33.2
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (122788933..122789895)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (134986287..134987249)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (125551212..125552174)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 1 subfamily L member 6 Neighboring gene spindle and kinetochore associated complex subunit 2 pseudogene 1 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr9:125565210-125566409 Neighboring gene olfactory receptor family 1 subfamily K member 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20242 Neighboring gene Sharpr-MPRA regulatory region 52 Neighboring gene phosducin like

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    olfactory receptor 5C1
    Names
    hRPK-465_F_21
    olfactory receptor 5C2
    olfactory receptor 9-F
    olfactory receptor, family 5, subfamily C, member 2 pseudogene

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001923.1NP_001001923.1  olfactory receptor 5C1

      See identical proteins and their annotated locations for NP_001001923.1

      Status: VALIDATED

      Source sequence(s)
      AB065725
      Consensus CDS
      CCDS35131.1
      UniProtKB/Swiss-Prot
      B2RN54, B9EGT0, Q8NGR4, Q96RC4
      UniProtKB/TrEMBL
      A0A126GW42, Q6IFM9
      Related
      ENSP00000362784.2, ENST00000373680.3
      Conserved Domains (1) summary
      cd15945
      Location:16307
      7tmA_OR5C1-like; olfactory receptor subfamily 5C1 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      122788933..122789895
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060933.1 Alternate T2T-CHM13v2.0

      Range
      134986287..134987249
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)