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    Msantd1 Myb/SANT-like DNA-binding domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 403174, updated on 28-Oct-2024

    Summary

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    Official Symbol
    Msantd1provided by MGI
    Official Full Name
    Myb/SANT-like DNA-binding domain containing 1provided by MGI
    Primary source
    MGI:MGI:2684990
    See related
    Ensembl:ENSMUSG00000051246 AllianceGenome:MGI:2684990
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm144; A930005I04Rik
    Summary
    Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to be active in nuclear body. Is expressed in ductus deferens; epididymis; esophagus; and testis. Orthologous to human MSANTD1 (Myb/SANT DNA binding domain containing 1). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    human all
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    Genomic context

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    See Msantd1 in Genome Data Viewer
    Location:
    5 B2; 5 17.94 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (35071581..35084333)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (34914593..34926989)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor kinase 4 Neighboring gene microRNA 467g Neighboring gene STARR-positive B cell enhancer ABC_E1050 Neighboring gene huntingtin Neighboring gene STARR-seq mESC enhancer starr_12848 Neighboring gene regulator of G-protein signaling 12 Neighboring gene STARR-seq mESC enhancer starr_12849 Neighboring gene microRNA 3097 Neighboring gene hepatocyte growth factor activator

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    2. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nuclear body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    myb/SANT-like DNA-binding domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310550.1 → NP_001297479.1  myb/SANT-like DNA-binding domain-containing protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001297479.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AK044284, AW490053
      Consensus CDS
      CCDS80265.1
      UniProtKB/TrEMBL
      A0A0J9YU52
      Related
      ENSMUSP00000144008.2, ENSMUST00000202205.2
      Conserved Domains (1) summary
      pfam13837
      Location:44 → 116
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    2. NM_207277.1 → NP_997160.1  myb/SANT-like DNA-binding domain-containing protein 1 isoform 1

      See identical proteins and their annotated locations for NP_997160.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK044284
      Consensus CDS
      CCDS19221.1
      UniProtKB/Swiss-Prot
      Q8BIL2
      Related
      ENSMUSP00000057362.2, ENSMUST00000050535.2
      Conserved Domains (1) summary
      pfam13837
      Location:43 → 125
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      35071581..35084333
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036165260.1 → XP_036021153.1  myb/SANT-like DNA-binding domain-containing protein 1 isoform X4

      Conserved Domains (1) summary
      pfam13837
      Location:31 → 96
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    2. XM_017320960.2 → XP_017176449.1  myb/SANT-like DNA-binding domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A0J9YU52
      Conserved Domains (1) summary
      pfam13837
      Location:44 → 116
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    3. XM_011240753.3 → XP_011239055.1  myb/SANT-like DNA-binding domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011239055.1

      UniProtKB/TrEMBL
      A0A1D5RLV8
      Related
      ENSMUSP00000148522.2, ENSMUST00000212362.2
      Conserved Domains (1) summary
      pfam13837
      Location:31 → 118
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    4. XM_006504012.4 → XP_006504075.1  myb/SANT-like DNA-binding domain-containing protein 1 isoform X2

      Conserved Domains (1) summary
      pfam13837
      Location:1 → 81
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BIL2.1 GenPept UniProtKB/Swiss-Prot:Q8BIL2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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