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    CEP170P1 centrosomal protein 170 pseudogene 1 [ Homo sapiens (human) ]

    Gene ID: 645455, updated on 10-Dec-2024

    Summary

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    Official Symbol
    CEP170P1provided by HGNC
    Official Full Name
    centrosomal protein 170 pseudogene 1provided by HGNC
    Primary source
    HGNC:HGNC:28364
    See related
    Ensembl:ENSG00000298466 AllianceGenome:HGNC:28364
    Gene type
    pseudo
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FAM68B; CEP170L; KIAA0470L
    Summary
    This locus appears to be a transcribed pseudogene similar to centrosomal protein 170kDa (CEP170). An approximately 50 kb region upstream of this locus also is homologous to CEP170, but is not transcribed. [provided by RefSeq, Jul 2008]
    Expression
    Biased expression in testis (RPKM 57.8), brain (RPKM 12.2) and 13 other tissues See more
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    Genomic context

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    See CEP170P1 in Genome Data Viewer
    Location:
    4q26
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (118516325..118554204)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (121821340..121859207)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (119437480..119475359)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105379403 Neighboring gene uncharacterized LOC124900767 Neighboring gene ReSE screen-validated silencer GRCh37_chr4:119437439-119437560 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:119452493-119452992 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:119454234-119454734 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:119454735-119455235 Neighboring gene ReSE screen-validated silencer GRCh37_chr4:119490834-119491031 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21847 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:119513527-119514434 Neighboring gene uncharacterized LOC729218 Neighboring gene RNA, U6 small nuclear 1054, pseudogene Neighboring gene capicua transcriptional repressor pseudogene 16

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Shifted Transversal Design smart-pooling for high coverage interactome mapping. Xin X, et al. Genome Res, 2009 Jul. PMID 19447967, Free PMC Article
    2. An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders. Chen S, et al. Nat Genet, 2018 Jul. PMID 29892012, Free PMC Article
    3. Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma. Mahlokozera T, et al. Nat Commun, 2021 Nov 3. PMID 34732716, Free PMC Article
    4. An inter-species protein-protein interaction network across vast evolutionary distance. Zhong Q, et al. Mol Syst Biol, 2016 Apr 22. PMID 27107014, Free PMC Article
    5. Next-generation sequencing to generate interactome datasets. Yu H, et al. Nat Methods, 2011 Jun. PMID 21516116, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • centrosomal protein 170kDa pseudogene 1

    Clone Names

    • KIAA0470, MGC26143

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_003135.3 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      AC092670
      Related
      ENST00000755695.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

      Range
      118516325..118554204
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060928.1 Alternate T2T-CHM13v2.0

      Range
      121821340..121859207
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_025246.1: Suppressed sequence

      Description
      NG_025246.1: This RefSeq was permanently suppressed because it is now thought that pseudogene is transcribed.

    2. NM_153243.2: Suppressed sequence

      Description
      NM_153243.2: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q96L14.2 GenPept UniProtKB/Swiss-Prot:Q96L14

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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