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    Gm1527 predicted gene 1527 [ Mus musculus (house mouse) ]

    Gene ID: 385263, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Gm1527provided by MGI
    Official Full Name
    predicted gene 1527provided by MGI
    Primary source
    MGI:MGI:2686373
    See related
    Ensembl:ENSMUSG00000074655 AllianceGenome:MGI:2686373
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm1136
    Summary
    Predicted to enable GTPase activator activity. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 5.1) See more
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    Genomic context

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    See Gm1527 in Genome Data Viewer
    Location:
    3 A3; 3 12.37 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (28946768..28980874)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (28892619..28926725)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E6046 Neighboring gene STARR-seq mESC enhancer starr_07266 Neighboring gene STARR-seq mESC enhancer starr_07267 Neighboring gene STARR-seq mESC enhancer starr_07268 Neighboring gene STARR-seq mESC enhancer starr_07269 Neighboring gene STARR-seq mESC enhancer starr_07271 Neighboring gene ribosomal protein L22 like 1 Neighboring gene predicted gene, 33051 Neighboring gene predicted gene, 33102 Neighboring gene STARR-seq mESC enhancer starr_07272 Neighboring gene STARR-seq mESC enhancer starr_07273 Neighboring gene STARR-seq mESC enhancer starr_07274 Neighboring gene predicted gene, 33154 Neighboring gene STARR-seq mESC enhancer starr_07276 Neighboring gene EGF-like and EMI domain containing 1 Neighboring gene STARR-seq mESC enhancer starr_07277 Neighboring gene microRNA 551b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    2. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    3. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    4. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article
    5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC385263

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033479.5 → NP_001028651.1  uncharacterized protein LOC385263

      See identical proteins and their annotated locations for NP_001028651.1

      Status: VALIDATED

      Source sequence(s)
      AC132583
      Consensus CDS
      CCDS38404.1
      UniProtKB/TrEMBL
      Q3V0P3
      Related
      ENSMUSP00000096773.2, ENSMUST00000099170.2
      Conserved Domains (3) summary
      cd13319
      Location:14 → 112
      PH_RARhoGAP; RA and RhoGAP domain-containing protein Pleckstrin homology PH domain
      cl02570
      Location:288 → 477
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
      cl28922
      Location:125 → 240
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      28946768..28980874
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319633.2 → XP_017175122.1  uncharacterized protein LOC385263 isoform X2

      UniProtKB/TrEMBL
      Q3V0P3
      Conserved Domains (3) summary
      cd13319
      Location:14 → 112
      PH_RARhoGAP; RA and RhoGAP domain-containing protein Pleckstrin homology PH domain
      cl02570
      Location:288 → 477
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
      cl28922
      Location:125 → 240
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    2. XM_030252663.1 → XP_030108523.1  uncharacterized protein LOC385263 isoform X1

      Conserved Domains (3) summary
      cd13319
      Location:14 → 112
      PH_RARhoGAP; RA and RhoGAP domain-containing protein Pleckstrin homology PH domain
      cl02570
      Location:288 → 477
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
      cl28922
      Location:125 → 240
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    3. XM_030252664.1 → XP_030108524.1  uncharacterized protein LOC385263 isoform X3

      Conserved Domains (3) summary
      cd13319
      Location:14 → 112
      PH_RARhoGAP; RA and RhoGAP domain-containing protein Pleckstrin homology PH domain
      cl02570
      Location:288 → 448
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
      cl28922
      Location:125 → 240
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    4. XM_030252665.1 → XP_030108525.1  uncharacterized protein LOC385263 isoform X3

      Conserved Domains (3) summary
      cd13319
      Location:14 → 112
      PH_RARhoGAP; RA and RhoGAP domain-containing protein Pleckstrin homology PH domain
      cl02570
      Location:288 → 448
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
      cl28922
      Location:125 → 240
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    5. XM_036163149.1 → XP_036019042.1  uncharacterized protein LOC385263 isoform X3

      Conserved Domains (3) summary
      cd13319
      Location:14 → 112
      PH_RARhoGAP; RA and RhoGAP domain-containing protein Pleckstrin homology PH domain
      cl02570
      Location:288 → 448
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
      cl28922
      Location:125 → 240
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    6. XM_017319634.1 → XP_017175123.1  uncharacterized protein LOC385263 isoform X4

      Conserved Domains (1) summary
      cl02570
      Location:91 → 280
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    Nucleotide Protein Strain
    Heading Accession and Version

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