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    Bpifb5 BPI fold containing family B, member 5 [ Mus musculus (house mouse) ]

    Gene ID: 228802, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Bpifb5provided by MGI
    Official Full Name
    BPI fold containing family B, member 5provided by MGI
    Primary source
    MGI:MGI:2385160
    See related
    Ensembl:ENSMUSG00000038572 AllianceGenome:MGI:2385160
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Lplunc5
    Summary
    Is expressed in lung and olfactory epithelium. Orthologous to human BPIFB5P (BPI fold containing family B member 5, pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in ovary adult (RPKM 15.2), testis adult (RPKM 4.4) and 2 other tissues See more
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    Genomic context

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    See Bpifb5 in Genome Data Viewer
    Location:
    2 H1; 2 76.28 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (154065662..154082822)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (154223742..154240902)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene BPI fold containing family A, member 5 Neighboring gene STARR-seq mESC enhancer starr_06112 Neighboring gene BPI fold containing family B, member 1 Neighboring gene CDK5 regulatory subunit associated protein 1 Neighboring gene STARR-seq mESC enhancer starr_06113 Neighboring gene STARR-seq mESC enhancer starr_06114 Neighboring gene BPI fold containing family B, member 9A Neighboring gene zinc finger protein 54-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Expansion of the Bactericidal/Permeability Increasing-like (BPI-like) protein locus in cattle. Wheeler TT, et al. BMC Genomics, 2007 Mar 15. PMID 17362520, Free PMC Article
    2. Phylogenetic and evolutionary analysis of the PLUNC gene family. Bingle CD, et al. Protein Sci, 2004 Feb. PMID 14739326, Free PMC Article
    3. A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis. Jones MR, et al. Front Genet, 2018. PMID 30728831, Free PMC Article
    4. Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily. Bingle CD, et al. Biochem Soc Trans, 2011 Aug. PMID 21787333, Free PMC Article
    5. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC27784

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    long palate lung and nasal epithelium protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144890.2 → NP_659139.2  long palate lung and nasal epithelium protein 5 precursor

      See identical proteins and their annotated locations for NP_659139.2

      Status: VALIDATED

      Source sequence(s)
      AK142982, AL732601
      Consensus CDS
      CCDS16928.1
      UniProtKB/TrEMBL
      Q3UQ05, Q8VEH9
      Related
      ENSMUSP00000046683.8, ENSMUST00000045959.8
      Conserved Domains (1) summary
      cl00188
      Location:130 → 226
      BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      154065662..154082822
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006499332.3 → XP_006499395.1  long palate lung and nasal epithelium protein 5 isoform X1

      UniProtKB/TrEMBL
      Q8VEH9
      Conserved Domains (1) summary
      cl00188
      Location:80 → 176
      BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...
    Nucleotide Protein Strain
    Heading Accession and Version

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