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    Zfp114 zinc finger protein 114 [ Mus musculus (house mouse) ]

    Gene ID: 232966, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Zfp114provided by MGI
    Official Full Name
    zinc finger protein 114provided by MGI
    Primary source
    MGI:MGI:3037815
    See related
    Ensembl:ENSMUSG00000068962 AllianceGenome:MGI:3037815
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm1957; Zfp110
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in rest of cerebellum mantle layer and ventral grey horn. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    human all
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    Genomic context

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    See Zfp114 in Genome Data Viewer
    Location:
    7 A3; 7 10.27 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (23874468..23886990)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (24175022..24183170)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 112 Neighboring gene STARR-positive B cell enhancer ABC_E2817 Neighboring gene zinc finger protein 235 Neighboring gene STARR-seq mESC enhancer starr_18251 Neighboring gene zinc finger protein 111 Neighboring gene zinc finger protein 109

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. Shannon M, et al. Genome Res, 2003 Jun. PMID 12743021, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC107483

    General protein information

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    Preferred Names
    zinc finger protein 221

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001029933.4 → NP_001025104.2  zinc finger protein 221 isoform a

      See identical proteins and their annotated locations for NP_001025104.2

      Status: VALIDATED

      Source sequence(s)
      AC138791
      Consensus CDS
      CCDS39826.1
      UniProtKB/TrEMBL
      Q3UTF4
      Related
      ENSMUSP00000146241.2, ENSMUST00000206547.2
      Conserved Domains (4) summary
      COG5048
      Location:344 → 585
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:336 → 356
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:8 → 48
      KRAB; KRAB box
      pfam13465
      Location:320 → 345
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001404000.1 → NP_001390929.1  zinc finger protein 221 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC138791
      UniProtKB/TrEMBL
      Q3UTF4

    3. NM_001404001.1 → NP_001390930.1  zinc finger protein 221 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC138791
      Related
      ENSMUSP00000083173.7, ENSMUST00000086010.7

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      23874468..23886990
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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