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    Omt2a oocyte maturation, alpha [ Mus musculus (house mouse) ]

    Gene ID: 18379, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Omt2aprovided by MGI
    Official Full Name
    oocyte maturation, alphaprovided by MGI
    Primary source
    MGI:MGI:106620
    See related
    Ensembl:ENSMUSG00000066463 AllianceGenome:MGI:106620
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    OM2a
    Summary
    Predicted to be located in cytosol. Is expressed in 2-cell stage embryo; oocyte; ovary; primary oocyte; and secondary oocyte. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Omt2a in Genome Data Viewer
    Location:
    9 E1; 9 43.65 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (78219254..78222079, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (78311972..78314797, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene developmental pluripotency associated 5C Neighboring gene glutathione S-transferase alpha 5 Neighboring gene oocyte maturation, beta Neighboring gene glutathione S-transferase, alpha 2 (Yc2)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Isolation and characterization of two novel, cytoplasmically polyadenylated, oocyte-specific, mouse maternal RNAs. West MF, et al. Dev Biol, 1996 Apr 10. PMID 8608859
    2. Oocytes in newborn MRL mouse testes. Otsuka S, et al. Biol Reprod, 2008 Jul. PMID 18354036
    3. Genetic regulation of mouse stem cells: identification of two keratinocyte stem cell regulatory loci. Popova NV, et al. Curr Top Microbiol Immunol, 2004. PMID 14594209
    4. Identification of two keratinocyte stem cell regulatory loci implicated in skin carcinogenesis. Popova NV, et al. Carcinogenesis, 2003 Mar. PMID 12663500
    5. Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Evsikov AV, et al. Genes Dev, 2006 Oct 1. PMID 17015433, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    oocyte maturation, alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001111286.2 → NP_001104756.1  oocyte maturation, alpha isoform 1

      See identical proteins and their annotated locations for NP_001104756.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer protein (isoform 1).
      Source sequence(s)
      AU015702, DV648064, DV649105
      Consensus CDS
      CCDS52867.1
      UniProtKB/TrEMBL
      G5E8X8
      Related
      ENSMUSP00000126342.3, ENSMUST00000166056.9

    2. NM_001164523.1 → NP_001157995.1  oocyte maturation, alpha isoform 2

      See identical proteins and their annotated locations for NP_001157995.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses a different segment for its 5' UTR and 5' coding region, compared to variant 1. The resulting protein (isoform 2) has a shorter and distinct N-terminus when it is compared to isoform 1.
      Source sequence(s)
      AA619817, AA693017, AU015702, BB698495
      Consensus CDS
      CCDS52868.1
      UniProtKB/TrEMBL
      G3X9W2
      Related
      ENSMUSP00000109003.3, ENSMUST00000113376.10

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      78219254..78222079 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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