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    ATP1A1-AS1 ATP1A1 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 84852, updated on 17-Sep-2024

    Summary

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    Official Symbol
    ATP1A1-AS1provided by HGNC
    Official Full Name
    ATP1A1 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:28262
    See related
    Ensembl:ENSG00000203865 MIM:618305; AllianceGenome:HGNC:28262
    Gene type
    ncRNA
    RefSeq status
    PREDICTED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ATP1A1OS; C1orf203
    Expression
    Ubiquitous expression in kidney (RPKM 93.4), duodenum (RPKM 80.0) and 25 other tissues See more
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    Genomic context

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    See ATP1A1-AS1 in Genome Data Viewer
    Location:
    1p13.1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (116392865..116418622, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (116400935..116426692, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (116935487..116961244, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378919 Neighboring gene uncharacterized LOC105378920 Neighboring gene small nucleolar RNA U3 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1229 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1230 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1559 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1560 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1561 Neighboring gene ATPase Na+/K+ transporting subunit alpha 1 Neighboring gene NANOG hESC enhancer GRCh37_chr1:116958386-116958887 Neighboring gene Sharpr-MPRA regulatory region 13778 Neighboring gene RNA, U6 small nuclear 817, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:116968695-116969196 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:116969197-116969696 Neighboring gene long intergenic non-protein coding RNA 1762 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:116985590-116985791 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:117013937-117014172 Neighboring gene HNF1 motif-containing MPRA enhancer 99 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:117020893-117021452 Neighboring gene uncharacterized LOC112268235 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:117025970-117026470 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1562

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Characterization of a Long Non-Coding RNA, the Antisense RNA of Na/K-ATPase α1 in Human Kidney Cells. Fan X, et al. Int J Mol Sci, 2018 Jul 21. PMID 30037072, Free PMC Article
    2. LncRNA ATP1A1-AS1 inhibits cell proliferation and promotes cell apoptosis in thyroid carcinoma by regulating the miR-620/IRF2BP2 axis. Jia J, et al. Am J Med Sci, 2023 Jan. PMID 36002076
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LncRNA ATP1A1-AS1 inhibits cell proliferation and promotes cell apoptosis in thyroid carcinoma by regulating the miR-620/IRF2BP2 axis.
      Title: LncRNA ATP1A1-AS1 inhibits cell proliferation and promotes cell apoptosis in thyroid carcinoma by regulating the miR-620/IRF2BP2 axis.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Other Names

    • ATP1A1 opposite strand

    Clone Names

    • MGC16179

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_024124.2 RNA Sequence

      Status: PREDICTED

      Description
      Transcript Variant: This variant (5) includes a terminal exon that overlaps, on the opposite strand, the terminus of the ATP1A1 gene (GeneID: 476).
      Source sequence(s)
      BC069003, BC098428

    2. NR_024125.2 RNA Sequence

      Status: PREDICTED

      Description
      Transcript Variant: This variant (4) includes an alternate exon compared to variant 5.
      Source sequence(s)
      AL136376, BC098428, BX389823
      Related
      ENST00000369492.5

    3. NR_024126.1 RNA Sequence

      Status: PREDICTED

      Description
      Transcript Variant: This variant (3) includes an alternate exon compared to variant 5.
      Source sequence(s)
      BC007373

    4. NR_027645.1 RNA Sequence

      Status: PREDICTED

      Description
      Transcript Variant: This variant (2) has an alternate terminal exon compared to variant 1.
      Source sequence(s)
      BC028281

    5. NR_027646.1 RNA Sequence

      Status: PREDICTED

      Description
      Transcript Variant: This variant (1) had an alternate terminal exon and overlaps, on the opposite strand, the the ATP1A1 gene (GeneID: 476).
      Source sequence(s)
      DC351073

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      116392865..116418622 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      116400935..116426692 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_032766.1: Suppressed sequence

      Description
      NM_032766.1: This RefSeq was permanently suppressed because it is now thought that this gene does not encode a protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5TC04.1 GenPept UniProtKB/Swiss-Prot:Q5TC04

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.