U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SLC4A4 solute carrier family 4 member 4 [ Homo sapiens (human) ]

    Gene ID: 8671, updated on 27-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SLC4A4provided by HGNC
    Official Full Name
    solute carrier family 4 member 4provided by HGNC
    Primary source
    HGNC:HGNC:11030
    See related
    Ensembl:ENSG00000080493 MIM:603345; AllianceGenome:HGNC:11030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    KNBC; NBC1; NBC2; pNBC; HNBC1; NBCe1; PRTAO; hhNMC; kNBC1; SLC4A5; NBCe1-A
    Summary
    This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
    Expression
    Biased expression in kidney (RPKM 56.0), pancreas (RPKM 31.5) and 12 other tissues See more
    Orthologs
    mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SLC4A4 in Genome Data Viewer
    Location:
    4q13.3
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (71062660..71572083)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (74404936..74914352)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (72052482..72437800)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124900711 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15472 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15473 Neighboring gene Sharpr-MPRA regulatory region 2882 Neighboring gene MOB kinase activator 1B Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15474 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21603 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:71869952-71870648 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21605 Neighboring gene ReSE screen-validated silencer GRCh37_chr4:71883900-71884096 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:71894495-71894995 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:71924658-71925260 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:71925261-71925861 Neighboring gene deoxycytidine kinase Neighboring gene uncharacterized LOC124900712 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:72061583-72062135 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:72165851-72166352 Neighboring gene probable UDP-sugar transporter protein SLC35A4 Neighboring gene SLC35A4 upstream open reading frame protein-like Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15475 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21606 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:72234371-72234872 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:72234873-72235372 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr4:72338203-72339402 Neighboring gene lactate dehydrogenase A like 6E, pseudogene Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:72458772-72459481 Neighboring gene uncharacterized LOC107986285 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr4:72479894-72481093 Neighboring gene uncharacterized LOC105377271 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr4:72519382-72520581

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Sequence- or position-specific mutations in the carboxyl-terminal FL motif of the kidney sodium bicarbonate cotransporter (NBC1) disrupt its basolateral targeting and alpha-helical structure. Li HC, et al. J Membr Biol, 2009 Mar. PMID 19294449
    2. The Na(+)/HCO3(-) Co-Transporter SLC4A4 Plays a Role in Growth and Migration of Colon and Breast Cancer Cells. Parks SK, et al. J Cell Physiol, 2015 Aug. PMID 25612232
    3. Interplay between disulfide bonding and N-glycosylation defines SLC4 Na+-coupled transporter extracellular topography. Zhu Q, et al. J Biol Chem, 2015 Feb 27. PMID 25568315, Free PMC Article
    4. Identification of membrane topography of the electrogenic sodium bicarbonate cotransporter pNBC1 by in vitro transcription/translation. Tatishchev S, et al. Biochemistry, 2003 Jan 28. PMID 12534288
    5. Phosphorylation-induced modulation of pNBC1 function: distinct roles for the amino- and carboxy-termini. Gross E, et al. J Physiol, 2003 Jun 15. PMID 12730338, Free PMC Article

    See all (111) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SLC4A4 is a novel driver of enzalutamide resistance in prostate cancer.
      Title: SLC4A4 is a novel driver of enzalutamide resistance in prostate cancer.
    2. Distal renal tubular acidosis, autoimmune thyroiditis, enamel hypomaturation, and tooth agenesis caused by homozygosity of a novel double-nucleotide substitution in SLC4A4.
      Title: Distal renal tubular acidosis, autoimmune thyroiditis, enamel hypomaturation, and tooth agenesis caused by homozygosity of a novel double-nucleotide substitution in SLC4A4.
    3. Extracellular vesicles derived from cancer-associated fibroblast carries miR-224-5p targeting SLC4A4 to promote the proliferation, invasion and migration of colorectal cancer cells.
      Title: Extracellular vesicles derived from cancer-associated fibroblast carries miR-224-5p targeting SLC4A4 to promote the proliferation, invasion and migration of colorectal cancer cells.
    4. A novel I551F variant of the Na(+)/HCO3(-) cotransporter NBCe1-A shows reduced cell surface expression, resulting in diminished transport activity.
      Title: A novel I551F variant of the Na(+)/HCO(3)(-) cotransporter NBCe1-A shows reduced cell surface expression, resulting in diminished transport activity.
    5. Sodium bicarbonate transporter NBCe1 regulates proliferation and viability of human prostate cancer cells LNCaP and PC3.
      Title: Sodium bicarbonate transporter NBCe1 regulates proliferation and viability of human prostate cancer cells LNCaP and PC3.
    6. Electrogenic sodium bicarbonate cotransporter NBCe1 regulates pancreatic beta cell function in type 2 diabetes.
      Title: Electrogenic sodium bicarbonate cotransporter NBCe1 regulates pancreatic β cell function in type 2 diabetes.
    7. Prognostic Value of SLC4A4 and its Correlation with Immune Infiltration in Colon Adenocarcinoma.
      Title: Prognostic Value of SLC4A4 and its Correlation with Immune Infiltration in Colon Adenocarcinoma.
    8. hsa_circRNA_001587 upregulates SLC4A4 expression to inhibit migration, invasion, and angiogenesis of pancreatic cancer cells via binding to microRNA-223.
      Title: hsa_circRNA_001587 upregulates SLC4A4 expression to inhibit migration, invasion, and angiogenesis of pancreatic cancer cells via binding to microRNA-223.
    9. SLC4A4 expression correlated negatively with miR-223-3p expression in patient samples. Given that miR-223-3p suppressed the SLC4A4/KRAS axis, miR-223-3p gene therapy could be an effective treatment for renal cancer.
      Title: MiR-223-3p promotes cell proliferation and metastasis by downregulating SLC4A4 in clear cell renal cell carcinoma.
    10. the sodium bicarbonate cotransporter NBCe1-B is expressed in rat and human thyroid
      Title: Expression, Localization, and Regulation of the Sodium Bicarbonate Cotransporter NBCe1 in the Thyroid.
    Submit: New GeneRIF Correction See all GeneRIFs (69)

    Phenotypes

    Go to the top of the page Help

    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Autosomal recessive proximal renal tubular acidosis
    MedGen: C1970309 OMIM: 604278 GeneReviews: Not available
    		Compare labs

    EBI GWAS Catalog

    Description
    Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants.
    EBI GWAS Catalog
    Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.
    EBI GWAS Catalog
    Impact of ancestry and common genetic variants on QT interval in African Americans.
    EBI GWAS Catalog
    Meta-analysis of genome-wide association studies in multiethnic Asians identifies two loci for age-related nuclear cataract.
    EBI GWAS Catalog

    Variation

    Go to the top of the page Help

    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • DKFZp781H1314

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables monoatomic anion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sodium:bicarbonate symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sodium:bicarbonate symporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables sodium:bicarbonate symporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables sodium:bicarbonate symporter activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables solute:inorganic anion antiporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables symporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in bicarbonate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in bicarbonate transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in bicarbonate transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in bicarbonate transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in bicarbonate transport TAS
    Traceable Author Statement
    more info
    		  
    involved_in inorganic anion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in monoatomic anion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of positive regulation of glycolytic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of positive regulation of glycolytic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in regulation of intracellular pH IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of regulation of intracellular pH IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of regulation of intracellular pH IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of intracellular pH IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of regulation of intracellular pH ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of regulation of membrane potential IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of regulation of membrane potential ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in sodium ion export across plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sodium ion transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transport across blood-brain barrier NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in basolateral plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in basolateral plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in basolateral plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in cell surface IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular exosome HDA PubMed 
    is_active_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    electrogenic sodium bicarbonate cotransporter 1
    Names
    Na(+)/HCO3(-) cotransporter
    kidney type Na+/HCO3- cotransporter
    pancreatic sodium bicarbonate cotransporter
    sodium bicarbonate cotransporter 1 (sodium bicarbonate cotransporter, kidney; sodium bicarbonate cotransporter, pancreas)
    solute carrier family 4 (sodium bicarbonate cotransporter), member 4
    solute carrier family 4, sodium bicarbonate cotransporter, member 4, brain type
    solute carrier family 4, sodium bicarbonate cotransporter, member 5

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_012653.2 RefSeqGene

      Range
      129107..514425
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001098484.3 → NP_001091954.1  electrogenic sodium bicarbonate cotransporter 1 isoform 1

      See identical proteins and their annotated locations for NP_001091954.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript.
      Source sequence(s)
      AC019089, AC079230, AC096713, AC110783
      Consensus CDS
      CCDS43236.1
      UniProtKB/Swiss-Prot
      C4B714, O15153, Q8NEJ2, Q9H262, Q9NRZ1, Q9UIC0, Q9UIC1, Q9UP50, Q9Y6R1
      UniProtKB/TrEMBL
      A0A8V8TNB1
      Related
      ENSP00000264485.5, ENST00000264485.11
      Conserved Domains (1) summary
      TIGR00834
      Location:109 → 1003
      ae; anion exchange protein

    2. NM_001134742.2 → NP_001128214.1  electrogenic sodium bicarbonate cotransporter 1 isoform 3

      See identical proteins and their annotated locations for NP_001128214.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) lacks an alternate exon in the 3' coding region that results in a frameshift, compared to variant 1. It encodes isoform 3 which has a longer and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AC019089, AC079230, AC096713, AC110783
      Consensus CDS
      CCDS47071.1
      UniProtKB/TrEMBL
      A0A8V8TNB1, A5JJ20
      Related
      ENSP00000393557.1, ENST00000425175.5
      Conserved Domains (3) summary
      TIGR00834
      Location:109 → 1003
      ae; anion exchange protein
      pfam00955
      Location:436 → 955
      HCO3_cotransp; HCO3- transporter family
      pfam07565
      Location:137 → 387
      Band_3_cyto; Band 3 cytoplasmic domain

    3. NM_003759.4 → NP_003750.1  electrogenic sodium bicarbonate cotransporter 1 isoform 2

      See identical proteins and their annotated locations for NP_003750.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and coding region, compared to variant 1. These differences cause translation initiation at a downstream AUG and an isoform (2) with a shorter and distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AC019089, AC079230, AC110783
      Consensus CDS
      CCDS3549.1
      UniProtKB/TrEMBL
      A0A8V8TNB1
      Related
      ENSP00000344272.3, ENST00000340595.4
      Conserved Domains (1) summary
      TIGR00834
      Location:65 → 959
      ae; anion exchange protein

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

      Range
      71062660..71572083
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024454268.2 → XP_024310036.1  electrogenic sodium bicarbonate cotransporter 1 isoform X2

      UniProtKB/TrEMBL
      A0A8V8TNB1
      Related
      ENSP00000513771.1, ENST00000698522.1
      Conserved Domains (1) summary
      TIGR00834
      Location:114 → 1008
      ae; anion exchange protein

    2. XM_024454269.2 → XP_024310037.1  electrogenic sodium bicarbonate cotransporter 1 isoform X2

      UniProtKB/TrEMBL
      A0A8V8TNB1
      Conserved Domains (1) summary
      TIGR00834
      Location:114 → 1008
      ae; anion exchange protein

    3. XM_024454270.2 → XP_024310038.1  electrogenic sodium bicarbonate cotransporter 1 isoform X3

      UniProtKB/Swiss-Prot
      C4B714, O15153, Q8NEJ2, Q9H262, Q9NRZ1, Q9UIC0, Q9UIC1, Q9UP50, Q9Y6R1
      UniProtKB/TrEMBL
      A0A8V8TNB1
      Related
      ENSP00000497468.1, ENST00000649996.1
      Conserved Domains (1) summary
      TIGR00834
      Location:109 → 1003
      ae; anion exchange protein

    4. XM_024454272.2 → XP_024310040.1  electrogenic sodium bicarbonate cotransporter 1 isoform X3

      UniProtKB/Swiss-Prot
      C4B714, O15153, Q8NEJ2, Q9H262, Q9NRZ1, Q9UIC0, Q9UIC1, Q9UP50, Q9Y6R1
      UniProtKB/TrEMBL
      A0A8V8TNB1
      Conserved Domains (1) summary
      TIGR00834
      Location:109 → 1003
      ae; anion exchange protein

    5. XM_024454271.2 → XP_024310039.1  electrogenic sodium bicarbonate cotransporter 1 isoform X3

      UniProtKB/Swiss-Prot
      C4B714, O15153, Q8NEJ2, Q9H262, Q9NRZ1, Q9UIC0, Q9UIC1, Q9UP50, Q9Y6R1
      UniProtKB/TrEMBL
      A0A8V8TNB1
      Conserved Domains (1) summary
      TIGR00834
      Location:109 → 1003
      ae; anion exchange protein

    6. XM_024454267.2 → XP_024310035.1  electrogenic sodium bicarbonate cotransporter 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V8TNB1
      Conserved Domains (1) summary
      TIGR00834
      Location:140 → 1034
      ae; anion exchange protein

    7. XM_017008792.2 → XP_016864281.1  electrogenic sodium bicarbonate cotransporter 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V8TNB1

    8. XM_047416348.1 → XP_047272304.1  electrogenic sodium bicarbonate cotransporter 1 isoform X7

    9. XM_017008793.2 → XP_016864282.1  electrogenic sodium bicarbonate cotransporter 1 isoform X5

    10. XM_011532390.3 → XP_011530692.1  electrogenic sodium bicarbonate cotransporter 1 isoform X6

      Conserved Domains (2) summary
      pfam00955
      Location:250 → 769
      HCO3_cotransp; HCO3- transporter family
      pfam07565
      Location:59 → 201
      Band_3_cyto; Band 3 cytoplasmic domain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060928.1 Alternate T2T-CHM13v2.0

      Range
      74404936..74914352
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054351152.1 → XP_054207127.1  electrogenic sodium bicarbonate cotransporter 1 isoform X2

    2. XM_054351153.1 → XP_054207128.1  electrogenic sodium bicarbonate cotransporter 1 isoform X2

    3. XM_054351155.1 → XP_054207130.1  electrogenic sodium bicarbonate cotransporter 1 isoform X3

      UniProtKB/Swiss-Prot
      C4B714, O15153, Q8NEJ2, Q9H262, Q9NRZ1, Q9UIC0, Q9UIC1, Q9UP50, Q9Y6R1

    4. XM_054351154.1 → XP_054207129.1  electrogenic sodium bicarbonate cotransporter 1 isoform X3

      UniProtKB/Swiss-Prot
      C4B714, O15153, Q8NEJ2, Q9H262, Q9NRZ1, Q9UIC0, Q9UIC1, Q9UP50, Q9Y6R1

    5. XM_054351156.1 → XP_054207131.1  electrogenic sodium bicarbonate cotransporter 1 isoform X3

      UniProtKB/Swiss-Prot
      C4B714, O15153, Q8NEJ2, Q9H262, Q9NRZ1, Q9UIC0, Q9UIC1, Q9UP50, Q9Y6R1

    6. XM_054351151.1 → XP_054207126.1  electrogenic sodium bicarbonate cotransporter 1 isoform X1

    7. XM_054351157.1 → XP_054207132.1  electrogenic sodium bicarbonate cotransporter 1 isoform X4

    8. XM_054351158.1 → XP_054207133.1  electrogenic sodium bicarbonate cotransporter 1 isoform X5

    9. XM_054351159.1 → XP_054207134.1  electrogenic sodium bicarbonate cotransporter 1 isoform X6

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9Y6R1.1 GenPept UniProtKB/Swiss-Prot:Q9Y6R1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous