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    PEG3 paternally expressed 3 [ Homo sapiens (human) ]

    Gene ID: 5178, updated on 26-Nov-2024

    Summary

    Official Symbol
    PEG3provided by HGNC
    Official Full Name
    paternally expressed 3provided by HGNC
    Primary source
    HGNC:HGNC:8826
    See related
    Ensembl:ENSG00000198300 MIM:601483; AllianceGenome:HGNC:8826
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PW1; ZNF904; ZSCAN24; ZKSCAN22
    Summary
    In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2009]
    Expression
    Biased expression in ovary (RPKM 126.4), placenta (RPKM 67.7) and 4 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See PEG3 in Genome Data Viewer
    Location:
    19q13.43
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (56810082..56840726, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (59905167..59935794, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (57321450..57352094, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily AH member 1 pseudogene Neighboring gene ZIM2 antisense RNA 1 Neighboring gene zinc finger imprinted 2 Neighboring gene PEG3 antisense RNA 1 Neighboring gene MER1 repeat containing imprinted transcript 1 Neighboring gene uncharacterized LOC124904779

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Copy number response

    Description
    Copy number response
    Haploinsufficency

    No evidence available (Last evaluated 2012-05-17)

    ClinGen Genome Curation Page
    Triplosensitivity

    No evidence available (Last evaluated 2012-05-17)

    ClinGen Genome Curation Page

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within regulation of gene expression ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in autophagosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    paternally-expressed gene 3 protein
    Names
    Kruppel-type zinc finger protein
    zinc finger and SCAN domain-containing protein 24

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_012989.1 RefSeqGene

      Range
      5004..35648
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001146184.2NP_001139656.1  paternally-expressed gene 3 protein isoform 1

      See identical proteins and their annotated locations for NP_001139656.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) is missing a 5' non-coding exon, therefore, has a shorter 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (1).
      Source sequence(s)
      AF208967, AF208968, AI089069, AK295679, BC037330, CR933682
      Consensus CDS
      CCDS12948.1
      UniProtKB/Swiss-Prot
      A7E2B8, B4DIM4, C9JP50, P78418, Q5H9P9, Q7Z7H7, Q8TF75, Q9GZU2, Q9GZY2
      UniProtKB/TrEMBL
      Q96Q96
      Related
      ENSP00000469486.1, ENST00000599577.5
      Conserved Domains (5) summary
      PHA00666
      Location:14211501
      PHA00666; putative protease
      sd00017
      Location:507527
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:969991
      zf-C2H2; Zinc finger, C2H2 type
      pfam02023
      Location:42124
      SCAN; SCAN domain
      pfam08648
      Location:141237
      DUF1777; Protein of unknown function (DUF1777)
    2. NM_001146185.2NP_001139657.1  paternally-expressed gene 3 protein isoform 2

      See identical proteins and their annotated locations for NP_001139657.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) is missing a 5' non-coding exon, and uses an alternate acceptor splice site at the first coding exon compared to variant 1. This results in the use of an in-frame downstream start codon, and an isoform (2) with a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      AF208967, AF208969, AI089069, AK295679, BC037330, CR933682
      Consensus CDS
      CCDS58685.1
      UniProtKB/TrEMBL
      B9EG68
      Related
      ENSP00000472402.1, ENST00000593695.5
      Conserved Domains (4) summary
      PHA00666
      Location:12951375
      PHA00666; putative protease
      sd00017
      Location:381401
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:843865
      zf-C2H2; Zinc finger, C2H2 type
      pfam08648
      Location:15111
      DUF1777; Protein of unknown function (DUF1777)
    3. NM_001146187.2NP_001139659.1  paternally-expressed gene 3 protein isoform 3

      See identical proteins and their annotated locations for NP_001139659.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) is missing a 5' non-coding exon, and uses alternate splice sites at several coding exons compared to variant 1. This results in the use of an in-frame downstream start codon, and an isoform (3) with a shorter N-terminus and two additional internal aa compared to isoform 1. Variants 5, 9-22, and 30 all encode the same isoform (3).
      Source sequence(s)
      AB006625, AF208967, AI089069, AK295679, BC037330, CR933682
      Consensus CDS
      CCDS58684.1
      UniProtKB/TrEMBL
      B9EG68
      Related
      ENSP00000473190.1, ENST00000598410.5
      Conserved Domains (3) summary
      PHA03169
      Location:12951379
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:383403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:845867
      zf-C2H2; Zinc finger, C2H2 type
    4. NM_001369717.1NP_001356646.1  paternally-expressed gene 3 protein isoform 4

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6), as well as variant 7, encodes the longest isoform (4).
      Source sequence(s)
      AC006115
      UniProtKB/TrEMBL
      Q96Q96
      Conserved Domains (4) summary
      PHA03169
      Location:14211505
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:509529
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:971993
      zf-C2H2; Zinc finger, C2H2 type
      pfam02023
      Location:42129
      SCAN; SCAN domain
    5. NM_001369718.1NP_001356647.1  paternally-expressed gene 3 protein isoform 4

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7), as well as variant 6, encodes the longest isoform (4).
      Source sequence(s)
      AC006115
      UniProtKB/TrEMBL
      Q96Q96
      Conserved Domains (4) summary
      PHA03169
      Location:14211505
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:509529
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:971993
      zf-C2H2; Zinc finger, C2H2 type
      pfam02023
      Location:42129
      SCAN; SCAN domain
    6. NM_001369719.1NP_001356648.1  paternally-expressed gene 3 protein isoform 5

      Status: REVIEWED

      Source sequence(s)
      AC006115
      UniProtKB/TrEMBL
      Q96Q96
      Conserved Domains (4) summary
      PHA03169
      Location:13901474
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:478498
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:940962
      zf-C2H2; Zinc finger, C2H2 type
      pfam02023
      Location:42129
      SCAN; SCAN domain
    7. NM_001369720.1NP_001356649.1  paternally-expressed gene 3 protein isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9), as well as variants 5, 10-22, and 30, encodes isoform 3.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS58684.1
      UniProtKB/TrEMBL
      B9EG68
      Related
      ENSP00000497332.1, ENST00000647852.1
      Conserved Domains (3) summary
      PHA03169
      Location:12951379
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:383403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:845867
      zf-C2H2; Zinc finger, C2H2 type
    8. NM_001369721.1NP_001356650.1  paternally-expressed gene 3 protein isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10), as well as variants 5, 9, 11-22, and 30, encodes isoform 3.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS58684.1
      UniProtKB/TrEMBL
      B9EG68
      Conserved Domains (3) summary
      PHA03169
      Location:12951379
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:383403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:845867
      zf-C2H2; Zinc finger, C2H2 type
    9. NM_001369722.1NP_001356651.1  paternally-expressed gene 3 protein isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11), as well as variants 5, 9, 10, 12-22, and 30, encodes isoform 3.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS58684.1
      UniProtKB/TrEMBL
      B9EG68
      Related
      ENSP00000497512.1, ENST00000649680.1
      Conserved Domains (3) summary
      PHA03169
      Location:12951379
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:383403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:845867
      zf-C2H2; Zinc finger, C2H2 type
    10. NM_001369723.1NP_001356652.1  paternally-expressed gene 3 protein isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12), as well as variants 5, 9-11, 13-22, and 30, encodes isoform 3.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS58684.1
      UniProtKB/TrEMBL
      B9EG68
      Related
      ENSP00000497466.1, ENST00000650102.1
      Conserved Domains (3) summary
      PHA03169
      Location:12951379
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:383403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:845867
      zf-C2H2; Zinc finger, C2H2 type
    11. NM_001369724.1NP_001356653.1  paternally-expressed gene 3 protein isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13), as well as variants 5, 9-12, 14-22, and 30, encodes isoform 3.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS58684.1
      UniProtKB/TrEMBL
      B9EG68
      Conserved Domains (3) summary
      PHA03169
      Location:12951379
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:383403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:845867
      zf-C2H2; Zinc finger, C2H2 type
    12. NM_001369725.1NP_001356654.1  paternally-expressed gene 3 protein isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (14), as well as variants 5, 9-13, 15-22, and 30, encodes isoform 3.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS58684.1
      UniProtKB/TrEMBL
      B9EG68
      Conserved Domains (3) summary
      PHA03169
      Location:12951379
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:383403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:845867
      zf-C2H2; Zinc finger, C2H2 type
    13. NM_001369726.1NP_001356655.1  paternally-expressed gene 3 protein isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (15), as well as variants 5, 9-14, 16-22, and 30, encodes isoform 3.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS58684.1
      UniProtKB/TrEMBL
      B9EG68
      Related
      ENSP00000497971.1, ENST00000650632.1
      Conserved Domains (3) summary
      PHA03169
      Location:12951379
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:383403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:845867
      zf-C2H2; Zinc finger, C2H2 type
    14. NM_001369727.1NP_001356656.1  paternally-expressed gene 3 protein isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (16), as well as variants 5, 9-15, 17-22, and 30, encodes isoform 3.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS58684.1
      UniProtKB/TrEMBL
      B9EG68
      Conserved Domains (3) summary
      PHA03169
      Location:12951379
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:383403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:845867
      zf-C2H2; Zinc finger, C2H2 type
    15. NM_001369728.1NP_001356657.1  paternally-expressed gene 3 protein isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (17), as well as variants 5, 9-16, 18-22, and 30, encodes isoform 3.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS58684.1
      UniProtKB/TrEMBL
      B9EG68
      Related
      ENSP00000496867.1, ENST00000649876.1
      Conserved Domains (3) summary
      PHA03169
      Location:12951379
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:383403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:845867
      zf-C2H2; Zinc finger, C2H2 type
    16. NM_001369729.1NP_001356658.1  paternally-expressed gene 3 protein isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (18), as well as variants 5, 9-17, 19-22, and 30, encodes isoform 3.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS58684.1
      UniProtKB/TrEMBL
      B9EG68
      Conserved Domains (3) summary
      PHA03169
      Location:12951379
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:383403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:845867
      zf-C2H2; Zinc finger, C2H2 type
    17. NM_001369730.1NP_001356659.1  paternally-expressed gene 3 protein isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (19), as well as variants 5, 9-18, 20-22, and 30, encodes isoform 3.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS58684.1
      UniProtKB/TrEMBL
      B9EG68
      Conserved Domains (3) summary
      PHA03169
      Location:12951379
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:383403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:845867
      zf-C2H2; Zinc finger, C2H2 type
    18. NM_001369731.1NP_001356660.1  paternally-expressed gene 3 protein isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (20), as well as variants 5, 9-19, 21, 22, and 30, encodes isoform 3.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS58684.1
      UniProtKB/TrEMBL
      B9EG68
      Related
      ENSP00000498047.1, ENST00000649233.1
      Conserved Domains (3) summary
      PHA03169
      Location:12951379
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:383403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:845867
      zf-C2H2; Zinc finger, C2H2 type
    19. NM_001369732.1NP_001356661.1  paternally-expressed gene 3 protein isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (21), as well as variants 5, 9-20, 22, and 30, encodes isoform 3.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS58684.1
      UniProtKB/TrEMBL
      B9EG68
      Conserved Domains (3) summary
      PHA03169
      Location:12951379
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:383403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:845867
      zf-C2H2; Zinc finger, C2H2 type
    20. NM_001369733.1NP_001356662.1  paternally-expressed gene 3 protein isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (22), as well as variants 5, 9-21, and 30, encodes isoform 3.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS58684.1
      UniProtKB/TrEMBL
      B9EG68
      Related
      ENSP00000498138.1, ENST00000649428.1
      Conserved Domains (3) summary
      PHA03169
      Location:12951379
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:383403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:845867
      zf-C2H2; Zinc finger, C2H2 type
    21. NM_001369734.1NP_001356663.1  paternally-expressed gene 3 protein isoform 6

      Status: REVIEWED

      Description
      Transcript Variant: This variant (23), as well as variants 24-27, encodes isoform 6.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS92696.1
      UniProtKB/TrEMBL
      A0A3B3IRU6, B9EG68
      Conserved Domains (3) summary
      PHA03169
      Location:12641348
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:352372
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:814836
      zf-C2H2; Zinc finger, C2H2 type
    22. NM_001369735.1NP_001356664.1  paternally-expressed gene 3 protein isoform 6

      Status: REVIEWED

      Description
      Transcript Variant: This variant (24), as well as variants 23 and 25-27, encodes isoform 6.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS92696.1
      UniProtKB/TrEMBL
      A0A3B3IRU6, B9EG68
      Conserved Domains (3) summary
      PHA03169
      Location:12641348
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:352372
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:814836
      zf-C2H2; Zinc finger, C2H2 type
    23. NM_001369736.1NP_001356665.1  paternally-expressed gene 3 protein isoform 6

      Status: REVIEWED

      Description
      Transcript Variant: This variant (25), as well as variants 23, 24, 26, and 27, encodes isoform 6.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS92696.1
      UniProtKB/TrEMBL
      A0A3B3IRU6, B9EG68
      Related
      ENSP00000496853.1, ENST00000647621.1
      Conserved Domains (3) summary
      PHA03169
      Location:12641348
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:352372
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:814836
      zf-C2H2; Zinc finger, C2H2 type
    24. NM_001369737.1NP_001356666.1  paternally-expressed gene 3 protein isoform 6

      Status: REVIEWED

      Description
      Transcript Variant: This variant (26), as well as variants 23-25 and 27, encodes isoform 6.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS92696.1
      UniProtKB/TrEMBL
      A0A3B3IRU6, B9EG68
      Conserved Domains (3) summary
      PHA03169
      Location:12641348
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:352372
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:814836
      zf-C2H2; Zinc finger, C2H2 type
    25. NM_001369738.1NP_001356667.1  paternally-expressed gene 3 protein isoform 6

      Status: REVIEWED

      Description
      Transcript Variant: This variant (27), as well as variants 23-26, encodes isoform 6.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS92696.1
      UniProtKB/TrEMBL
      A0A3B3IRU6, B9EG68
      Conserved Domains (3) summary
      PHA03169
      Location:12641348
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:352372
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:814836
      zf-C2H2; Zinc finger, C2H2 type
    26. NM_001369739.1NP_001356668.1  paternally-expressed gene 3 protein isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (30), as well as variants 5 and 9-22, encodes isoform 3.
      Source sequence(s)
      AC006115
      Consensus CDS
      CCDS58684.1
      UniProtKB/TrEMBL
      B9EG68
      Related
      ENSP00000496914.1, ENST00000648694.1
      Conserved Domains (3) summary
      PHA03169
      Location:12951379
      PHA03169; hypothetical protein; Provisional
      sd00017
      Location:383403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:845867
      zf-C2H2; Zinc finger, C2H2 type
    27. NM_006210.3NP_006201.1  paternally-expressed gene 3 protein isoform 1

      See identical proteins and their annotated locations for NP_006201.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes isoform 1. Variants 1 and 2 both encode the same isoform (1).
      Source sequence(s)
      AF208967, AI089069, AK295679, BC037330, CR933682
      Consensus CDS
      CCDS12948.1
      UniProtKB/Swiss-Prot
      A7E2B8, B4DIM4, C9JP50, P78418, Q5H9P9, Q7Z7H7, Q8TF75, Q9GZU2, Q9GZY2
      UniProtKB/TrEMBL
      Q96Q96
      Related
      ENSP00000326581.7, ENST00000326441.15
      Conserved Domains (5) summary
      PHA00666
      Location:14211501
      PHA00666; putative protease
      sd00017
      Location:507527
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:969991
      zf-C2H2; Zinc finger, C2H2 type
      pfam02023
      Location:42124
      SCAN; SCAN domain
      pfam08648
      Location:141237
      DUF1777; Protein of unknown function (DUF1777)

    RNA

    1. NR_161475.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC006115
    2. NR_161476.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC006115

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      56810082..56840726 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      59905167..59935794 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001146186.1: Suppressed sequence

      Description
      NM_001146186.1: This RefSeq was removed because currently there is insufficient support for the 5' end of the transcript.