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    PIDD1 p53-induced death domain protein 1 [ Homo sapiens (human) ]

    Gene ID: 55367, updated on 27-Nov-2024

    Summary

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    Official Symbol
    PIDD1provided by HGNC
    Official Full Name
    p53-induced death domain protein 1provided by HGNC
    Primary source
    HGNC:HGNC:16491
    See related
    Ensembl:ENSG00000177595 MIM:605247; AllianceGenome:HGNC:16491
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    LRDD; PIDD; MRT75
    Summary
    The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
    Expression
    Ubiquitous expression in testis (RPKM 3.7), spleen (RPKM 3.6) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See PIDD1 in Genome Data Viewer
    Location:
    11p15.5
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (799184..809501, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (850616..861222, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (799184..805231, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3029 Neighboring gene cell cycle exit and neuronal differentiation 1 Neighboring gene solute carrier family 25 member 22 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:794229-794747 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:795266-795784 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3032 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:796302-796820 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4279 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4280 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4281 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:797857-798373 Neighboring gene proapoptotic nucleolar protein 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:804161-804858 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3034 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4284 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4285 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4286 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3035 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:811306-812046 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:812047-812787 Neighboring gene ribosomal protein lateral stalk subunit P2 Neighboring gene small nucleolar RNA, H/ACA box 52 Neighboring gene Sharpr-MPRA regulatory region 11801 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3036 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4287 Neighboring gene patatin like phospholipase domain containing 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Molecular basis of neurodevelopmental disorders caused by pathogenic variants of PIDD. Ha HJ, et al. Biochem Biophys Res Commun, 2023 Feb 19. PMID 36689811
    2. PIDD4, a novel PIDD isoform without the LRR domain, can independently induce cell apoptosis in cytoplasm. Huang L, et al. Biochem Biophys Res Commun, 2011 Apr 1. PMID 21371439
    3. Low expression of PIDD is associated with cell proliferation and apoptosis in hepatocellular carcinoma. Shi W, et al. Tumour Biol, 2016 Aug. PMID 26846109
    4. Extra centrosomes induce PIDD1-mediated inflammation and immunosurveillance. Garcia-Carpio I, et al. EMBO J, 2023 Oct 16. PMID 37530438, Free PMC Article
    5. Pathogenic variants in PIDD1 lead to an autosomal recessive neurodevelopmental disorder with pachygyria and psychiatric features. Zaki MS, et al. Eur J Hum Genet, 2021 Aug. PMID 34163010, Free PMC Article

    See all (48) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Extra centrosomes induce PIDD1-mediated inflammation and immunosurveillance.
      Title: Extra centrosomes induce PIDD1-mediated inflammation and immunosurveillance.
    2. Molecular basis of neurodevelopmental disorders caused by pathogenic variants of PIDD.
      Title: Molecular basis of neurodevelopmental disorders caused by pathogenic variants of PIDD.
    3. Pathogenic variants in PIDD1 lead to an autosomal recessive neurodevelopmental disorder with pachygyria and psychiatric features.
      Title: Pathogenic variants in PIDD1 lead to an autosomal recessive neurodevelopmental disorder with pachygyria and psychiatric features.
    4. ATR signalling mediates the prosurvival function of phospho-NPM against PIDDosome mediated cell death.
      Title: ATR signalling mediates the prosurvival function of phospho-NPM against PIDDosome mediated cell death.
    5. Biallelic mutations in the death domain of PIDD1 impair caspase-2 activation and are associated with intellectual disability.
      Title: Biallelic mutations in the death domain of PIDD1 impair caspase-2 activation and are associated with intellectual disability.
    6. PIDD interaction with KEAP1 as a new mutation-independent mechanism to promote NRF2 stabilization and chemoresistance in NSCLC.
      Title: PIDD interaction with KEAP1 as a new mutation-independent mechanism to promote NRF2 stabilization and chemoresistance in NSCLC.
    7. Attention-deficit/hyperactivity disorder risk alleles correlated with increased expression (and decreased methylation) of ARTN and PIDD1 and with a decreased expression (and increased methylation) of C2orf82.
      Title: Exploring genetic variation that influences brain methylation in attention-deficit/hyperactivity disorder.
    8. Whole exome sequencing (WES) of an affected fetus, and subsequent Sanger sequencing of the second fetus, revealed a homozygous frameshift variant in CRADD, which encodes an adaptor protein that interacts with PIDD and caspase-2 to initiate apoptosis
      Title: Homozygous null variant in CRADD, encoding an adaptor protein that mediates apoptosis, is associated with lissencephaly.
    9. NPM1-dependent nucleolar PIDDosome is a key initiator of the caspase-2 activation cascade.
      Title: NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus.
    10. PIDD expression was lower in HCC tissues and HCC cell lines, compared with the adjacent non-tumorous tissues and LO2 normal hepatocytes. PIDD could serve as an independent prognostic factor to predict the survival of HCC patients. PIDD facilitated cell cycle progression and accelerated cell proliferation in HepG2 cells, while overexpression of PIDD resulted in cell cycle arrest at G1 phase in Hep3B cells.
      Title: Low expression of PIDD is associated with cell proliferation and apoptosis in hepatocellular carcinoma.
    Submit: New GeneRIF Correction See all GeneRIFs (25)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Intellectual developmental disorder, autosomal recessive 75, with neuropsychiatric features and variant lissencephaly
    MedGen: C5676961 OMIM: 619827 GeneReviews: Not available
    		not available

    Variation

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    See Variation Viewer (GRCh37.p13)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC16925, DKFZp434D229

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables death receptor binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables endopeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage response IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in DNA damage response NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in extrinsic apoptotic signaling pathway via death domain receptors IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in positive regulation of cysteine-type endopeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein autoprocessing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of canonical NF-kappaB signal transduction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in signal transduction TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		  
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    part_of endopeptidase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in nucleolus NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    p53-induced death domain-containing protein 1
    Names
    leucine-rich repeat and death domain-containing protein
    leucine-rich repeats and death domain containing
    p53-induced protein with a death domain

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145886.4 → NP_665893.2  p53-induced death domain-containing protein 1 isoform 1

      See identical proteins and their annotated locations for NP_665893.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AF274972, BQ214414, BX349115, CN427946
      Consensus CDS
      CCDS7716.1
      UniProtKB/Swiss-Prot
      Q59FD1, Q59H10, Q59HC7, Q7Z4P8, Q8NC89, Q8NDL2, Q96C25, Q9HB75, Q9NRE6
      Related
      ENSP00000337797.5, ENST00000347755.10
      Conserved Domains (6) summary
      cd00116
      Location:117 → 279
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd08779
      Location:788 → 873
      Death_PIDD; Death Domain of p53-induced protein with a death domain
      sd00033
      Location:127 → 152
      LRR_RI; leucine-rich repeat [structural motif]
      pfam10461
      Location:421 → 453
      Peptidase_S68; Peptidase S68
      pfam13855
      Location:194 → 252
      LRR_8; Leucine rich repeat
      cl02517
      Location:325 → 398
      ZU5; ZU5 domain

    2. NM_145887.4 → NP_665894.2  p53-induced death domain-containing protein 1 isoform 3

      See identical proteins and their annotated locations for NP_665894.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in an isoform (3) that is shorter than isoform 1.
      Source sequence(s)
      BC014904, BQ059356, BX349115, CN427946
      Consensus CDS
      CCDS44508.1
      UniProtKB/Swiss-Prot
      Q9HB75
      Related
      ENSP00000416801.2, ENST00000411829.6
      Conserved Domains (7) summary
      cd00116
      Location:117 → 279
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd08779
      Location:771 → 856
      Death_PIDD; Death Domain of p53-induced protein with a death domain
      sd00033
      Location:127 → 152
      LRR_RI; leucine-rich repeat [structural motif]
      pfam10461
      Location:421 → 453
      Peptidase_S68; Peptidase S68
      pfam13855
      Location:194 → 252
      LRR_8; Leucine rich repeat
      cl00467
      Location:666 → 856
      Ntn_hydrolase; The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid. N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a ...
      cl02517
      Location:325 → 398
      ZU5; ZU5 domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      799184..809501 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011520210.4 → XP_011518512.1  p53-induced death domain-containing protein 1 isoform X4

      See identical proteins and their annotated locations for XP_011518512.1

      UniProtKB/Swiss-Prot
      Q59FD1, Q59H10, Q59HC7, Q7Z4P8, Q8NC89, Q8NDL2, Q96C25, Q9HB75, Q9NRE6
      Conserved Domains (6) summary
      cd00116
      Location:117 → 279
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd08779
      Location:788 → 873
      Death_PIDD; Death Domain of p53-induced protein with a death domain
      sd00033
      Location:127 → 152
      LRR_RI; leucine-rich repeat [structural motif]
      pfam10461
      Location:421 → 453
      Peptidase_S68; Peptidase S68
      pfam13855
      Location:194 → 252
      LRR_8; Leucine rich repeat
      cl02517
      Location:325 → 398
      ZU5; ZU5 domain

    2. XM_005253005.6 → XP_005253062.1  p53-induced death domain-containing protein 1 isoform X2

      See identical proteins and their annotated locations for XP_005253062.1

      Conserved Domains (6) summary
      cd00116
      Location:117 → 279
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd08779
      Location:812 → 897
      Death_PIDD; Death Domain of p53-induced protein with a death domain
      sd00033
      Location:127 → 152
      LRR_RI; leucine-rich repeat [structural motif]
      pfam10461
      Location:421 → 453
      Peptidase_S68; Peptidase S68
      pfam13855
      Location:194 → 252
      LRR_8; Leucine rich repeat
      cl02517
      Location:325 → 398
      ZU5; ZU5 domain

    3. XM_011520209.4 → XP_011518511.1  p53-induced death domain-containing protein 1 isoform X3

      Conserved Domains (7) summary
      cd00116
      Location:144 → 306
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd08779
      Location:798 → 883
      Death_PIDD; Death Domain of p53-induced protein with a death domain
      sd00033
      Location:154 → 179
      LRR_RI; leucine-rich repeat [structural motif]
      pfam10461
      Location:448 → 480
      Peptidase_S68; Peptidase S68
      pfam13855
      Location:221 → 279
      LRR_8; Leucine rich repeat
      cl00467
      Location:693 → 883
      Ntn_hydrolase; The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid. N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a ...
      cl02517
      Location:352 → 425
      ZU5; ZU5 domain

    4. XM_047427240.1 → XP_047283196.1  p53-induced death domain-containing protein 1 isoform X1

    5. XM_047427239.1 → XP_047283195.1  p53-induced death domain-containing protein 1 isoform X12

    6. XM_047427238.1 → XP_047283194.1  p53-induced death domain-containing protein 1 isoform X11

    7. XM_005253006.6 → XP_005253063.1  p53-induced death domain-containing protein 1 isoform X2

      See identical proteins and their annotated locations for XP_005253063.1

      Conserved Domains (6) summary
      cd00116
      Location:117 → 279
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd08779
      Location:812 → 897
      Death_PIDD; Death Domain of p53-induced protein with a death domain
      sd00033
      Location:127 → 152
      LRR_RI; leucine-rich repeat [structural motif]
      pfam10461
      Location:421 → 453
      Peptidase_S68; Peptidase S68
      pfam13855
      Location:194 → 252
      LRR_8; Leucine rich repeat
      cl02517
      Location:325 → 398
      ZU5; ZU5 domain

    8. XM_047427243.1 → XP_047283199.1  p53-induced death domain-containing protein 1 isoform X8

    9. XM_047427242.1 → XP_047283198.1  p53-induced death domain-containing protein 1 isoform X7

    10. XM_047427241.1 → XP_047283197.1  p53-induced death domain-containing protein 1 isoform X6

    11. XM_011520212.3 → XP_011518514.1  p53-induced death domain-containing protein 1 isoform X5

      See identical proteins and their annotated locations for XP_011518514.1

      Conserved Domains (6) summary
      cd08779
      Location:666 → 751
      Death_PIDD; Death Domain of p53-induced protein with a death domain
      sd00033
      Location:7 → 26
      LRR_RI; leucine-rich repeat [structural motif]
      pfam10461
      Location:275 → 307
      Peptidase_S68; Peptidase S68
      pfam12799
      Location:95 → 134
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:48 → 106
      LRR_8; Leucine rich repeat
      cl02517
      Location:179 → 252
      ZU5; ZU5 domain

    12. XM_047427246.1 → XP_047283202.1  p53-induced death domain-containing protein 1 isoform X10

    13. XM_011520213.3 → XP_011518515.1  p53-induced death domain-containing protein 1 isoform X9

      Conserved Domains (3) summary
      cd08779
      Location:499 → 584
      Death_PIDD; Death Domain of p53-induced protein with a death domain
      pfam10461
      Location:108 → 140
      Peptidase_S68; Peptidase S68
      cl02517
      Location:12 → 85
      ZU5; ZU5 domain

    14. XM_047427245.1 → XP_047283201.1  p53-induced death domain-containing protein 1 isoform X9

    15. XM_047427244.1 → XP_047283200.1  p53-induced death domain-containing protein 1 isoform X13

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      850616..861222 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054369310.1 → XP_054225285.1  p53-induced death domain-containing protein 1 isoform X2

    2. XM_054369312.1 → XP_054225287.1  p53-induced death domain-containing protein 1 isoform X4

    3. XM_054369309.1 → XP_054225284.1  p53-induced death domain-containing protein 1 isoform X1

    4. XM_054369311.1 → XP_054225286.1  p53-induced death domain-containing protein 1 isoform X3

    5. XM_054369314.1 → XP_054225289.1  p53-induced death domain-containing protein 1 isoform X2

    6. XM_054369308.1 → XP_054225283.1  p53-induced death domain-containing protein 1 isoform X14

    7. XM_054369318.1 → XP_054225293.1  p53-induced death domain-containing protein 1 isoform X8

    8. XM_054369317.1 → XP_054225292.1  p53-induced death domain-containing protein 1 isoform X7

    9. XM_054369316.1 → XP_054225291.1  p53-induced death domain-containing protein 1 isoform X6

    10. XM_054369315.1 → XP_054225290.1  p53-induced death domain-containing protein 1 isoform X5

    11. XM_054369322.1 → XP_054225297.1  p53-induced death domain-containing protein 1 isoform X10

    12. XM_054369321.1 → XP_054225296.1  p53-induced death domain-containing protein 1 isoform X9

    13. XM_054369320.1 → XP_054225295.1  p53-induced death domain-containing protein 1 isoform X9

    14. XM_054369313.1 → XP_054225288.1  p53-induced death domain-containing protein 1 isoform X15

    15. XM_054369319.1 → XP_054225294.1  p53-induced death domain-containing protein 1 isoform X16

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_018494.3: Suppressed sequence

      Description
      NM_018494.3: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9HB75.2 GenPept UniProtKB/Swiss-Prot:Q9HB75

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