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    SLC35E1 solute carrier family 35 member E1 [ Homo sapiens (human) ]

    Gene ID: 79939, updated on 9-Dec-2024

    Summary

    Official Symbol
    SLC35E1provided by HGNC
    Official Full Name
    solute carrier family 35 member E1provided by HGNC
    Primary source
    HGNC:HGNC:20803
    See related
    Ensembl:ENSG00000127526 MIM:620337; AllianceGenome:HGNC:20803
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Predicted to enable antiporter activity. Predicted to be involved in transmembrane transport. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in prostate (RPKM 12.3), lung (RPKM 10.1) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See SLC35E1 in Genome Data Viewer
    Location:
    19p13.11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (16549837..16572415, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (16684627..16707204, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (16660648..16683226, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:16606743-16607243 Neighboring gene chromosome 19 open reading frame 44 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10302 Neighboring gene calcium homeostasis endoplasmic reticulum protein Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10303 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10304 Neighboring gene RNA, 7SL, cytoplasmic 146, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14237 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:16680351-16680851 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10305 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10306 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:16683261-16684135 Neighboring gene uncharacterized LOC105372295 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10308 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:16692801-16693372 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:16693373-16693944 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14239 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:16695630-16696166 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:16696804-16697686 Neighboring gene mediator complex subunit 26 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14242 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14243 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14244 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14245 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:16702872-16703374 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10309 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14246 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:16716746-16717543 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10310 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:16739143-16740074 Neighboring gene uncharacterized LOC105372296 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14247

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ14251, FLJ36689, MGC44954, DKFZp564G0462

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables antiporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    solute carrier family 35 member E1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024881.5NP_079157.3  solute carrier family 35 member E1

      See identical proteins and their annotated locations for NP_079157.3

      Status: VALIDATED

      Source sequence(s)
      AC008764, BC062562, BU619655
      Consensus CDS
      CCDS12346.2
      UniProtKB/Swiss-Prot
      Q8NBQ2, Q96JV7, Q96K37
      UniProtKB/TrEMBL
      H7C1I0
      Related
      ENSP00000470652.1, ENST00000595753.6
      Conserved Domains (1) summary
      pfam03151
      Location:29333
      TPT; Triose-phosphate Transporter family

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      16549837..16572415 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      16684627..16707204 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)