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    FHL1 four and a half LIM domains 1 [ Homo sapiens (human) ]

    Gene ID: 2273, updated on 12-Nov-2024

    Summary

    Official Symbol
    FHL1provided by HGNC
    Official Full Name
    four and a half LIM domains 1provided by HGNC
    Primary source
    HGNC:HGNC:3702
    See related
    Ensembl:ENSG00000022267 MIM:300163; AllianceGenome:HGNC:3702
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    KYOT; SLIM; FCMSU; FHL-1; FHL1A; FHL1B; FLH1A; SLIM1; XMPMA; RBMX1A; RBMX1B; SLIM-1; SLIMMER
    Summary
    This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.[provided by RefSeq, Nov 2009]
    Expression
    Broad expression in heart (RPKM 286.6), fat (RPKM 281.6) and 18 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See FHL1 in Genome Data Viewer
    Location:
    Xq26.3
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (136146702..136211359)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (134455091..134519750)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (135228861..135293518)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chrX:135179522-135180721 Neighboring gene E2F transcription factor 6 pseudogene 4 Neighboring gene ReSE screen-validated silencer GRCh37_chrX:135196669-135196868 Neighboring gene small nucleolar RNA U13 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chrX:135225551-135226750 Neighboring gene Sharpr-MPRA regulatory region 1893 Neighboring gene MAP7 domain containing 3 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 21026 Neighboring gene serine/threonine kinase 24 pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    Myopathy, reducing body, X-linked, childhood-onset
    MedGen: C4225159 OMIM: 300718 GeneReviews: Not available
    not available
    Myopathy, reducing body, X-linked, early-onset, severe
    MedGen: C4225423 OMIM: 300717 GeneReviews: Not available
    not available
    Uruguay Faciocardiomusculoskeletal syndrome
    MedGen: C1846010 OMIM: 300280 GeneReviews: Not available
    not available
    X-linked myopathy with postural muscle atrophy not available
    X-linked scapuloperoneal muscular dystrophy
    MedGen: C2678061 OMIM: 300695 GeneReviews: Not available
    not available

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC111107

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transmembrane transporter binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transmembrane transporter binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
     
    located_in focal adhesion HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    four and a half LIM domains protein 1
    Names
    LIM protein SLIMMER
    four-and-a-half Lin11, Isl-1 and Mec-3 domains 1
    skeletal muscle LIM-protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_015895.1 RefSeqGene

      Range
      5134..68955
      Download
      GenBank, FASTA, Sequence Viewer (Graphics), LRG_739

    mRNA and Protein(s)

    1. NM_001159699.2NP_001153171.1  four and a half LIM domains protein 1 isoform 5

      See identical proteins and their annotated locations for NP_001153171.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR, 3' UTR, and 3' coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded protein (isoform 5) has distinct N- and C-termini and is shorter than isoform 1.
      Source sequence(s)
      BC088369, BM995585, DC373386
      Consensus CDS
      CCDS55506.1
      UniProtKB/TrEMBL
      Q53FI7
      Related
      ENSP00000359717.1, ENST00000370683.6
      Conserved Domains (5) summary
      cd09344
      Location:56109
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09348
      Location:233296
      LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09424
      Location:117174
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09429
      Location:178230
      LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:2149
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    2. NM_001159700.2NP_001153172.1  four and a half LIM domains protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001153172.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, 3' UTR, and 3' coding region compared to variant 1. The encoded protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. Variants 2, 3, 4 and 9 encode the same protein (isoform 2).
      Source sequence(s)
      AK304680, AL078638, BC088369, BM995585, DC363191
      Consensus CDS
      CCDS14655.1
      UniProtKB/TrEMBL
      Q53FI7
      Related
      ENSP00000485897.1, ENST00000630084.2
      Conserved Domains (5) summary
      cd09344
      Location:4093
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09348
      Location:217280
      LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09424
      Location:101158
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09429
      Location:162214
      LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:533
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    3. NM_001159701.2NP_001153173.1  four and a half LIM domains protein 1 isoform 3 precursor

      See identical proteins and their annotated locations for NP_001153173.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR, 3' UTR, and coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded protein (isoform 3) is shorter and has distinct N- and C-termini, compared to isoform 1.
      Source sequence(s)
      AK301642, BC010998, BM995585
      Consensus CDS
      CCDS55505.1
      UniProtKB/TrEMBL
      Q53FI7
      Related
      ENSP00000437673.1, ENST00000539015.5
      Conserved Domains (5) summary
      cd09344
      Location:69122
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09348
      Location:246309
      LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09424
      Location:130187
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09429
      Location:191243
      LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:3462
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    4. NM_001159702.3NP_001153174.1  four and a half LIM domains protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001153174.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longest protein (isoform 1).
      Source sequence(s)
      AF063002, AF098518, BC010998, BM995585
      Consensus CDS
      CCDS55507.1
      UniProtKB/Swiss-Prot
      B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
      Related
      ENSP00000377710.2, ENST00000394155.8
      Conserved Domains (4) summary
      cd09344
      Location:4093
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09424
      Location:101158
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09429
      Location:162214
      LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:533
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    5. NM_001159703.2NP_001153175.1  four and a half LIM domains protein 1 isoform 4

      See identical proteins and their annotated locations for NP_001153175.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR and coding region, compared to variant 1. The encoded protein (isoform 4) is shorter than isoform 1.
      Source sequence(s)
      AF220153, AK301642, AL078638, BC010998, BE965488, BM995585, DA497183
      Consensus CDS
      CCDS76036.1
      UniProtKB/TrEMBL
      A0A0D9SFZ9
      Related
      ENSP00000477609.1, ENST00000618438.4
      Conserved Domains (3) summary
      cd09344
      Location:4093
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09424
      Location:101158
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:533
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    6. NM_001159704.1NP_001153176.1  four and a half LIM domains protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001153176.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR, 3' UTR, and 3' coding region compared to variant 1. The encoded protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. Variants 2, 3, 4 and 9 encode the same protein (isoform 2).
      Source sequence(s)
      AK122708, AL078638, BM995585
      Consensus CDS
      CCDS14655.1
      UniProtKB/TrEMBL
      Q53FI7
      Related
      ENSP00000443333.1, ENST00000543669.5
      Conserved Domains (5) summary
      cd09344
      Location:4093
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09348
      Location:217280
      LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09424
      Location:101158
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09429
      Location:162214
      LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:533
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    7. NM_001167819.1NP_001161291.1  four and a half LIM domains protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001161291.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) uses a different segment for its 5' UTR and lacks an alternate exon in the 3' coding region, compared to variant 1. The encoded protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. Variants 2, 3, 4 and 9 encode the same protein (isoform 2).
      Source sequence(s)
      BC010998, BM995585, DA917361, DA982372
      Consensus CDS
      CCDS14655.1
      UniProtKB/TrEMBL
      Q53FI7
      Related
      ENSP00000377709.2, ENST00000394153.6
      Conserved Domains (5) summary
      cd09344
      Location:4093
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09348
      Location:217280
      LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09424
      Location:101158
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09429
      Location:162214
      LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:533
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    8. NM_001330659.2NP_001317588.1  four and a half LIM domains protein 1 isoform 6

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10) uses an alternate 5'-terminal exon, lacks two in-frame exons in the 3' coding region, and uses an alternate start codon, compared to variant 1. The encoded isoform (6) is shorter and has a distinct N-terminus, compared to isoform 1.
      Source sequence(s)
      AL078638
      Consensus CDS
      CCDS83493.1
      UniProtKB/TrEMBL
      A0A0D9SFZ9, Q5JXI2
      Related
      ENSP00000359710.3, ENST00000370676.7
      Conserved Domains (3) summary
      cd09344
      Location:56109
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09424
      Location:117174
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:2149
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    9. NM_001369326.1NP_001356255.1  four and a half LIM domains protein 1 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AL078638
      Consensus CDS
      CCDS55507.1
      UniProtKB/Swiss-Prot
      B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
      Related
      ENSP00000498684.1, ENST00000651089.1
      Conserved Domains (4) summary
      cd09344
      Location:4093
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09424
      Location:101158
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09429
      Location:162214
      LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:533
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    10. NM_001369327.2NP_001356256.1  four and a half LIM domains protein 1 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AL078638
      Consensus CDS
      CCDS55507.1
      UniProtKB/Swiss-Prot
      B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
      Conserved Domains (4) summary
      cd09344
      Location:4093
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09424
      Location:101158
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09429
      Location:162214
      LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:533
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    11. NM_001369328.1NP_001356257.1  four and a half LIM domains protein 1 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AL078638
      Consensus CDS
      CCDS55507.1
      UniProtKB/Swiss-Prot
      B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
      Conserved Domains (4) summary
      cd09344
      Location:4093
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09424
      Location:101158
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09429
      Location:162214
      LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:533
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    12. NM_001369329.1NP_001356258.1  four and a half LIM domains protein 1 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AL078638
      Consensus CDS
      CCDS14655.1
      UniProtKB/TrEMBL
      Q53FI7
      Conserved Domains (5) summary
      cd09344
      Location:4093
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09348
      Location:217280
      LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09424
      Location:101158
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09429
      Location:162214
      LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:533
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    13. NM_001369330.1NP_001356259.1  four and a half LIM domains protein 1 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AL078638
      Consensus CDS
      CCDS14655.1
      UniProtKB/TrEMBL
      Q53FI7
      Related
      ENSP00000444815.1, ENST00000535737.5
      Conserved Domains (5) summary
      cd09344
      Location:4093
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09348
      Location:217280
      LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09424
      Location:101158
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09429
      Location:162214
      LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:533
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    14. NM_001369331.1NP_001356260.1  four and a half LIM domains protein 1 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AL078638
      Consensus CDS
      CCDS14655.1
      UniProtKB/TrEMBL
      Q53FI7
      Related
      ENSP00000359708.1, ENST00000370674.3
      Conserved Domains (5) summary
      cd09344
      Location:4093
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09348
      Location:217280
      LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09424
      Location:101158
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09429
      Location:162214
      LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:533
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    15. NM_001449.5NP_001440.2  four and a half LIM domains protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001440.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, 3' UTR, and 3' coding region compared to variant 1. The encoded protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. Variants 2, 3, 4 and 9 encode the same protein (isoform 2).
      Source sequence(s)
      BC010998, BM995585
      Consensus CDS
      CCDS14655.1
      UniProtKB/TrEMBL
      Q53FI7
      Related
      ENSP00000499016.1, ENST00000651929.2
      Conserved Domains (5) summary
      cd09344
      Location:4093
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09348
      Location:217280
      LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09424
      Location:101158
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09429
      Location:162214
      LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:533
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    RNA

    1. NR_027621.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) includes an additional exon at the 5' end, compared to variant 1. This variant is represented as non-coding because it contains an upstream ORF that is predicted to interfere with translation of the downstream expected ORF as used in variant 1.
      Source sequence(s)
      AK289411, AL078638, BC010998, BM995585

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      136146702..136211359
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047441926.1XP_047297882.1  four and a half LIM domains protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
    2. XM_047441927.1XP_047297883.1  four and a half LIM domains protein 1 isoform X3

    3. XM_024452354.2XP_024308122.1  four and a half LIM domains protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
      Conserved Domains (4) summary
      cd09344
      Location:4093
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09424
      Location:101158
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09429
      Location:162214
      LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:533
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    4. XM_047441925.1XP_047297881.1  four and a half LIM domains protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
    5. XM_006724743.3XP_006724806.1  four and a half LIM domains protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006724806.1

      Conserved Domains (4) summary
      cd09344
      Location:56109
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09424
      Location:117174
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09429
      Location:178230
      LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:2149
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    6. XM_006724746.4XP_006724809.1  four and a half LIM domains protein 1 isoform X2

      See identical proteins and their annotated locations for XP_006724809.1

      UniProtKB/Swiss-Prot
      B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
      Conserved Domains (4) summary
      cd09344
      Location:4093
      LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
      cd09424
      Location:101158
      LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cd09429
      Location:162214
      LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
      cl02475
      Location:533
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      134455091..134519750
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054326701.1XP_054182676.1  four and a half LIM domains protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
    2. XM_054326702.1XP_054182677.1  four and a half LIM domains protein 1 isoform X3

    3. XM_054326700.1XP_054182675.1  four and a half LIM domains protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
    4. XM_054326699.1XP_054182674.1  four and a half LIM domains protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
    5. XM_054326697.1XP_054182672.1  four and a half LIM domains protein 1 isoform X1

    6. XM_054326698.1XP_054182673.1  four and a half LIM domains protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630