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    ARL14EPL ARF like GTPase 14 effector protein like [ Homo sapiens (human) ]

    Gene ID: 644100, updated on 27-Nov-2024

    Summary

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    Official Symbol
    ARL14EPLprovided by HGNC
    Official Full Name
    ARF like GTPase 14 effector protein likeprovided by HGNC
    Primary source
    HGNC:HGNC:44201
    See related
    Ensembl:ENSG00000268223 AllianceGenome:HGNC:44201
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    mouse all
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    Genomic context

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    See ARL14EPL in Genome Data Viewer
    Location:
    5q23.1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (116032472..116059489)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (116544843..116571873)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (115368169..115395186)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22940 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22941 Neighboring gene lincRNA adipogenesis and lipogenesis associated Neighboring gene DEAD-box helicase 43 pseudogene 1 Neighboring gene laeverin Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22942 Neighboring gene ribosomal protein S25 pseudogene 6 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22943 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22944 Neighboring gene Sharpr-MPRA regulatory region 6 Neighboring gene MPRA-validated peak5429 silencer Neighboring gene COMM domain containing 10 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16257 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:115527171-115527671 Neighboring gene RNA, U6 small nuclear 644, pseudogene Neighboring gene high mobility group nucleosomal binding domain 2 pseudogene 27

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Spindle Assembly Checkpoint Inhibition Can Resensitize p53-Null Stem Cells to Cancer Chemotherapy. Liu C, et al. Cancer Res, 2019 May 1. PMID 30862715, Free PMC Article
    2. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. Dias Neto E, et al. Proc Natl Acad Sci U S A, 2000 Mar 28. PMID 10737800, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    ARL14 effector protein-like
    Names
    ADP ribosylation factor like GTPase 14 effector protein like
    ADP-ribosylation factor-like 14 effector protein-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195581.2 → NP_001182510.1  ARL14 effector protein-like isoform 1

      See identical proteins and their annotated locations for NP_001182510.1

      Status: VALIDATED

      Source sequence(s)
      AC034236
      Consensus CDS
      CCDS59490.1
      UniProtKB/Swiss-Prot
      P0DKL9
      Related
      ENSP00000510304.1, ENST00000686077.1
      Conserved Domains (1) summary
      pfam14949
      Location:36 → 138
      ARF7EP_C; ARF7 effector protein C-terminus

    2. NM_001385024.1 → NP_001371953.1  ARL14 effector protein-like isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC034236
      Conserved Domains (1) summary
      pfam14949
      Location:1 → 72
      ARF7EP_C; ARF7 effector protein C-terminus

    3. NM_001393974.1 → NP_001380903.1  ARL14 effector protein-like isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC034236
      Consensus CDS
      CCDS59490.1
      UniProtKB/Swiss-Prot
      P0DKL9
      Related
      ENSP00000472409.1, ENST00000601302.3
      Conserved Domains (1) summary
      pfam14949
      Location:36 → 138
      ARF7EP_C; ARF7 effector protein C-terminus

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      116032472..116059489
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      116544843..116571873
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0DKL9.1 GenPept UniProtKB/Swiss-Prot:P0DKL9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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