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    GLIDR glioblastoma down-regulated RNA [ Homo sapiens (human) ]

    Gene ID: 389741, updated on 22-Oct-2024

    Summary

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    Official Symbol
    GLIDRprovided by HGNC
    Official Full Name
    glioblastoma down-regulated RNAprovided by HGNC
    Primary source
    HGNC:HGNC:48823
    See related
    Ensembl:ENSG00000278175 AllianceGenome:HGNC:48823
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FAM88A; LINC01172; TCONS_00015562
    Expression
    Ubiquitous expression in thyroid (RPKM 3.8), brain (RPKM 3.6) and 25 other tissues See more
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    Genomic context

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    See GLIDR in Genome Data Viewer
    Location:
    9p12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (39803496..39810159, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (39817620..39824283, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (41948514..41955177, complement)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene RBPJ pseudogene 5 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:41926459-41927010 Neighboring gene CNTNAP3 pseudogene 6 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:41936783-41937617 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:41942506-41943030 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:41943031-41943555 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28420 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28421 Neighboring gene fibroblast growth factor 7 pseudogene 3 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr9:41997761-41998747 Neighboring gene family with sequence similarity 88 member D Neighboring gene RNA, 7SL, cytoplasmic 763, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Increased expression of long non-coding RNA GLIDR in prostate cancer. Zhang Y, et al. Cancer Biomark, 2017. PMID 28211799
    2. GLIDR promotes the aggressiveness progression of prostate cancer cells by sponging miR-128-3p. Li S, et al. Pathol Res Pract, 2023 Feb. PMID 36709726
    3. Long non-coding RNA GLIDR accelerates the tumorigenesis of lung adenocarcinoma by miR-1270/TCF12 axis. Tai G, et al. Cell Cycle, 2021 Sep. PMID 34369267, Free PMC Article
    4. A long non-coding RNA signature in glioblastoma multiforme predicts survival. Zhang XQ, et al. Neurobiol Dis, 2013 Oct. PMID 23726844
    5. Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism. Antoniali G, et al. Nat Commun, 2017 Oct 6. PMID 28986522, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. GLIDR promotes the aggressiveness progression of prostate cancer cells by sponging miR-128-3p.
      Title: GLIDR promotes the aggressiveness progression of prostate cancer cells by sponging miR-128-3p.
    2. Long non-coding RNA GLIDR accelerates the tumorigenesis of lung adenocarcinoma by miR-1270/TCF12 axis.
      Title: Long non-coding RNA GLIDR accelerates the tumorigenesis of lung adenocarcinoma by miR-1270/TCF12 axis.
    3. Increased GLIDR expression is associated with prostate cancer.
      Title: Increased expression of long non-coding RNA GLIDR in prostate cancer.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • Putative UPF0633 protein MGC21881
    • family with sequence similarity 88 member A
    • long intergenic non-protein coding RNA 1172

    Clone Names

    • MGC21881

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_015363.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript.
      Source sequence(s)
      BX664615
      Related
      ENST00000618092.4

    2. NR_126044.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the 3' exon, and terminates early and is shorter than variant 1.
      Source sequence(s)
      BX664615
      Related
      ENST00000625350.1

    3. NR_126045.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice site and lacks an internal segment, and terminates early and is shorter than variant 1.
      Source sequence(s)
      BX664615
      Related
      ENST00000839125.1

    4. NR_126046.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs at both the 5' and 3' ends, and is shorter than variant 1.
      Source sequence(s)
      BC019880, BX664615
      Related
      ENST00000666906.4

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      39803496..39810159 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060933.1 Alternate T2T-CHM13v2.0

      Range
      39817620..39824283 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_203448.1: Suppressed sequence

      Description
      NM_203448.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A6NN06.1 GenPept UniProtKB/Swiss-Prot:A6NN06

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials