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    LOC4342584 ATP-dependent DNA helicase 2 subunit KU70-like [ Oryza sativa Japonica Group (Japanese rice) ]

    Gene ID: 4342584, updated on 17-Jul-2024

    Summary

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    Gene symbol
    LOC4342584
    Gene description
    ATP-dependent DNA helicase 2 subunit KU70-like
    Locus tag
    OSNPB_070184900
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Oryza sativa Japonica Group
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa
    Also known as
    KU70; OsKU70; OsJ_23357; OsJ_23359; OJ1046_F10.128; OJ1046_F10.128-1; OJ1046_F10.128-2
    Expression
    Ubiquitous expression in flower buds (RPKM 7.5), leaves before flowering (RPKM 7.2) and 6 other tissues See more
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    Genomic context

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    See LOC4342584 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_06 current ASM3414082v1 (GCF_034140825.1) 7 NC_089041.1 (4545997..4557037)
    102 previous assembly IRGSP-1.0 (GCF_001433935.1) 7 NC_029262.1 (4485182..4496250)

    Chromosome 7 - NC_089041.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA J26 Neighboring gene histone H1 Neighboring gene uncharacterized LOC107281761 Neighboring gene probable serine/threonine-protein kinase WNK3 Neighboring gene uncharacterized LOC4342587

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome profiling of various organs at different developmental stages in rice Transcriptome profiling of various organs at different developmental stages in rice
    • Description: Transcriptom profiling in flower buds, flowers, flag leaves and roots sampled before flowering and after flowering, milk grains and mature seeds
    • BioProject: PRJNA243371
    • Publication: PMID 26387578
    • Analysis date: Fri Dec 15 20:02:59 2017

    Bibliography

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    Related articles in PubMed

    1. Suppression of Ku70/80 or Lig4 leads to decreased stable transformation and enhanced homologous recombination in rice. Nishizawa-Yokoi A, et al. New Phytol, 2012 Dec. PMID 23050791, Free PMC Article
    2. OsKu70 is associated with developmental growth and genome stability in rice. Hong JP, et al. Plant Physiol, 2010 Jan. PMID 19923234, Free PMC Article
    3. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Rice Full-Length cDNA Consortium, et al. Science, 2003 Jul 18. PMID 12869764

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Ku70 knockdown leads to decreased Agrobacterium-mediated stable transformation and enhanced homologous recombination in rice.
      Title: Suppression of Ku70/80 or Lig4 leads to decreased stable transformation and enhanced homologous recombination in rice.
    2. These results suggest that OsKu70 is required for the maintenance of chromosome stability and normal developmental growth in rice plants.
      Title: OsKu70 is associated with developmental growth and genome stability in rice.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables damaged DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables telomeric DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in double-strand break repair via nonhomologous end joining IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in telomere maintenance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Ku70:Ku80 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    aTP-dependent DNA helicase 2 subunit KU70
    Names
    ATP-dependent DNA helicase 2 subunit 1
    ATP-dependent DNA helicase 2 subunit KU70
    ATP-dependent DNA helicase II 70 kDa subunit
    LOC_Os07g08729
    putative ATP-dependent DNA helicase II 70 kDa subunit
    putative DNA-dependent protein kinase 70 kda DNA-binding subunit Ku70
    NP_001389956.1
    NP_001389957.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001403027.1 → NP_001389956.1  aTP-dependent DNA helicase 2 subunit KU70 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AK102066, CI600082, CI616946
      UniProtKB/Swiss-Prot
      A0A0N7KN15, A3BH97, B9FVV9, Q7F1L9, Q7F1M0

    2. NM_001403028.1 → NP_001389957.1  aTP-dependent DNA helicase 2 subunit KU70 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK102066, CI600082, CI616946

    RNA

    1. NR_175332.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AK099980, AK102066, CI600082, CI616946

    RefSeqs of Annotated Genomes: GCF_034140825.1-RS_2024_06

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM3414082v1 Primary Assembly

    Genomic

    1. NC_089041.1 Reference ASM3414082v1 Primary Assembly

      Range
      4545997..4557037
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7F1M0.1 GenPept UniProtKB/Swiss-Prot:Q7F1M0

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