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    pkib protein kinase (cAMP-dependent, catalytic) inhibitor beta [ Danio rerio (zebrafish) ]

    Gene ID: 797348, updated on 2-Nov-2024

    Summary

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    Official Symbol
    pkibprovided by ZNC
    Official Full Name
    protein kinase (cAMP-dependent, catalytic) inhibitor betaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041014-312
    See related
    Ensembl:ENSDARG00000053110 AllianceGenome:ZFIN:ZDB-GENE-041014-312
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7054531; si:dkey-150h13.1
    Summary
    Predicted to enable cAMP-dependent protein kinase inhibitor activity. Predicted to act upstream of or within negative regulation of protein kinase activity. Predicted to be active in cytoplasm and nucleus. Orthologous to human PKIB (cAMP-dependent protein kinase inhibitor beta). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See pkib in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (40371897..40451112, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (40474787..40554002, complement)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene sphingomyelin phosphodiesterase acid like 3A Neighboring gene fatty acid binding protein 7, brain, b Neighboring gene serine incorporator 1 Neighboring gene heat shock transcription factor 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables cAMP-dependent protein kinase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cAMP-dependent protein kinase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cAMP-dependent protein kinase inhibitor beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001122945.2 → NP_001116417.1  cAMP-dependent protein kinase inhibitor beta

      Status: VALIDATED

      Source sequence(s)
      AL845365, BC133889, EH444643
      UniProtKB/TrEMBL
      A0A8M1NG02, Q5SPN9
      Related
      ENSDARP00000069577.5, ENSDART00000075092.6
      Conserved Domains (1) summary
      pfam02827
      Location:2 → 70
      PKI; cAMP-dependent protein kinase inhibitor

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      40371897..40451112 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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