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    agpat5 1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon) [ Danio rerio (zebrafish) ]

    Gene ID: 767778, updated on 9-Dec-2024

    Summary

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    Official Symbol
    agpat5provided by ZNC
    Official Full Name
    1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-914
    See related
    Ensembl:ENSDARG00000063187 AllianceGenome:ZFIN:ZDB-GENE-060929-914
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc35d05; wu:fc35d05; zgc:154071
    Summary
    Predicted to enable acyltransferase activity. Predicted to be involved in phosphatidylinositol acyl-chain remodeling. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum and mitochondrion. Orthologous to human AGPAT5 (1-acylglycerol-3-phosphate O-acyltransferase 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See agpat5 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (6257452..6279684, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (6129006..6151012, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137487360 Neighboring gene tubulin, alpha 4 like Neighboring gene microcephalin 1 Neighboring gene angiopoietin 2a Neighboring gene uncharacterized LOC101884841

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC154071

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables 1-acylglycerol-3-phosphate O-acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phosphatidylinositol acyl-chain remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon
    NP_001070213.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076745.2 → NP_001070213.2  1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

      Status: VALIDATED

      Source sequence(s)
      CB359574, CU929061
      UniProtKB/TrEMBL
      A0A8M1NAW1, F1QDN6
      Related
      ENSDARP00000086538.4, ENSDART00000092105.6
      Conserved Domains (2) summary
      cd07990
      Location:63 → 263
      LPLAT_LCLAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like
      pfam16076
      Location:258 → 327
      Acyltransf_C; Acyltransferase C-terminus

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      6257452..6279684 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_011005848.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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