zdhhc8b zinc finger DHHC-type palmitoyltransferase 8b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zdhhc8bprovided by ZNC
Official Full Name: zinc finger DHHC-type palmitoyltransferase 8bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030407-3
See related: Ensembl:ENSDARG00000018508 AllianceGenome:ZFIN:ZDB-GENE-030407-3
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zisp; zdhhc5
Summary: Predicted to enable palmitoyltransferase activity. Predicted to be involved in peptidyl-L-cysteine S-palmitoylation and positive regulation of cholesterol efflux. Predicted to be located in Golgi membrane and mitochondrial membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including central nervous system; eye; lens placode; solid lens vesicle; and yolk syncytial layer. Orthologous to human ZDHHC8 (zinc finger DHHC-type palmitoyltransferase 8). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (17881080..18007077, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (17377084..17503081, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fe38b05.x1 (e-PCR)
- UniSTS:196453

z50384 (e-PCR), detects polymorphism
- UniSTS:238742

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables palmitoyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables palmitoyltransferase activity	IEA Inferred from Electronic Annotation more info
enables protein-cysteine S-palmitoyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in peptidyl-L-cysteine S-palmitoylation	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of cholesterol efflux	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: palmitoyltransferase ZDHHC8B

Names: membrane-associated DHHC8 zinc finger protein; probable palmitoyltransferase ZDHHC8; zinc finger DHHC domain-containing protein 8B; zinc finger DHHC-type containing 8b; zinc finger, DHHC domain containing 5

NP_840089.3

EC 2.3.1.225

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.