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    apom apolipoprotein M [ Danio rerio (zebrafish) ]

    Gene ID: 569714, updated on 2-Nov-2024

    Summary

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    Official Symbol
    apomprovided by ZNC
    Official Full Name
    apolipoprotein Mprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-010605-5
    See related
    Ensembl:ENSDARG00000076838 AllianceGenome:ZFIN:ZDB-GENE-010605-5
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb62d12; wu:fb62d12; si:ch211-235o23.2
    Summary
    Predicted to be located in extracellular region. Is expressed in liver. Human ortholog(s) of this gene implicated in coronary artery disease; type 1 diabetes mellitus; and type 2 diabetes mellitus. Orthologous to human APOM (apolipoprotein M). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See apom in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (42228741..42234561, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (42379323..42385143, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene intraflagellar transport 57 homolog (Chlamydomonas) Neighboring gene transmembrane protein 71 Neighboring gene finTRIM family, member 2 Neighboring gene finTRIM family, member 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Embryonic Atrazine Exposure Elicits Alterations in Genes Associated with Neuroendocrine Function in Adult Male Zebrafish. Wirbisky SE, et al. Toxicol Sci, 2016 Sep. PMID 27413107, Free PMC Article
    2. Parental vitamin deficiency affects the embryonic gene expression of immune-, lipid transport- and apolipoprotein genes. Skjærven KH, et al. Sci Rep, 2016 Oct 12. PMID 27731423, Free PMC Article
    3. Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation. Ung CY, et al. BMC Genomics, 2010 Mar 30. PMID 20353558, Free PMC Article
    4. Wdr5-mediated H3K4me3 coordinately regulates cell differentiation, proliferation termination, and survival in digestive organogenesis. Zhang Z, et al. Cell Death Discov, 2023 Jul 5. PMID 37407577, Free PMC Article
    5. Cdx1b protects intestinal cell fate by repressing signaling networks for liver specification. Jin Q, et al. J Genet Genomics, 2022 Dec. PMID 36460297

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    apolipoprotein M

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001199728.1 → NP_001186657.1  apolipoprotein M

      Status: VALIDATED

      Source sequence(s)
      EH485615, EH504863
      UniProtKB/TrEMBL
      A0A8M1NXE0
      Related
      ENSDARP00000123136.1, ENSDART00000141358.3
      Conserved Domains (1) summary
      cl21528
      Location:6 → 189
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      42228741..42234561 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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