rae1 ribonucleic acid export 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rae1provided by ZNC
Official Full Name: ribonucleic acid export 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1029
See related: Ensembl:ENSDARG00000007196 AllianceGenome:ZFIN:ZDB-GENE-040426-1029
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:56449; zgc:77723
Summary: Predicted to enable RNA binding activity and ubiquitin binding activity. Predicted to be involved in RNA export from nucleus; regulation of mitotic spindle organization; and transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery. Predicted to act upstream of or within cell division. Predicted to be located in mitotic spindle pole. Predicted to be part of nuclear pore. Orthologous to human RAE1 (ribonucleic acid export 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (22326613..22334062)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (20266367..20273840)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fa02h08.s1 (e-PCR)
- UniSTS:202153

fc49d10.x1 (e-PCR)
- UniSTS:194012

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in RNA export from nucleus	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cell division	IEA Inferred from Electronic Annotation more info
involved_in regulation of mitotic spindle organization	ISS Inferred from Sequence or Structural Similarity more info
involved_in transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in mitotic spindle pole	ISS Inferred from Sequence or Structural Similarity more info
part_of nuclear pore	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in spindle pole	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mRNA export factor

Names: RAE1 RNA export 1 homolog; mRNA-associated protein mrnp 41; rae1 protein homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200998.1 → NP_957292.1 mRNA export factor

See identical proteins and their annotated locations for NP_957292.1

Status: PROVISIONAL

Source sequence(s)

BC049445

UniProtKB/Swiss-Prot

Q6P037, Q7ZWF0

Related

ENSDARP00000015105.6, ENSDART00000020333.8

Conserved Domains (3) summary

COG2319
Location:39 → 337

WD40; WD40 repeat [General function prediction only]

sd00039
Location:42 → 84

7WD40; WD40 repeat [structural motif]

cl02567
Location:41 → 335

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007117.7 Reference GRCz11 Primary Assembly

Range

22326613..22334062

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005166220.5 → XP_005166277.1 mRNA export factor isoform X1

UniProtKB/Swiss-Prot

Q6P037, Q7ZWF0

UniProtKB/TrEMBL

A0A2R8QJS5, A0A8M2BDK5

Conserved Domains (3) summary

COG2319
Location:39 → 337

WD40; WD40 repeat [General function prediction only]

sd00039
Location:42 → 84

7WD40; WD40 repeat [structural motif]

cl02567
Location:40 → 335

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...