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    lmbrd2a LMBR1 domain containing 2a [ Danio rerio (zebrafish) ]

    Gene ID: 550238, updated on 14-Nov-2024

    Summary

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    Official Symbol
    lmbrd2aprovided by ZNC
    Official Full Name
    LMBR1 domain containing 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-32
    See related
    Ensembl:ENSDARG00000099566 AllianceGenome:ZFIN:ZDB-GENE-050417-32
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    lmbrd2; zgc:110095
    Summary
    Predicted to be involved in adrenergic receptor signaling pathway. Predicted to be active in membrane. Is expressed in several structures, including alar plate midbrain region; hatching gland; otic placode; polster; and solid lens vesicle. Orthologous to human LMBRD2 (LMBR1 domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See lmbrd2a in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (8194848..8238771)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (7691626..7733078)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene NIPBL cohesin loading factor a Neighboring gene solute carrier family 1 member 3a Neighboring gene family with sequence similarity 111.2 Neighboring gene family with sequence similarity 111.1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    G-protein coupled receptor-associated protein LMBRD2a
    Names
    LMBR1 domain containing 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017576.2 → NP_001017576.2  G-protein coupled receptor-associated protein LMBRD2a isoform 2

      Status: PROVISIONAL

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      CU469496
      UniProtKB/TrEMBL
      A0A286YBR1, A0A8M1N593
      Related
      ENSDARP00000144642.2, ENSDART00000174564.2

    2. NM_001327914.1 → NP_001314843.1  G-protein coupled receptor-associated protein LMBRD2a isoform 1

      Status: PROVISIONAL

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      CU469496, FP017293
      UniProtKB/TrEMBL
      A0A0R4IWA8, A0A8M1P374
      Related
      ENSDARP00000140984.2, ENSDART00000161261.2
      Conserved Domains (1) summary
      pfam04791
      Location:14 → 547
      LMBR1; LMBR1-like membrane protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      8194848..8238771
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021476149.2 → XP_021331824.1  G-protein coupled receptor-associated protein LMBRD2a isoform X1

      UniProtKB/TrEMBL
      A0A8M3B9B9
      Conserved Domains (1) summary
      pfam04791
      Location:14 → 550
      LMBR1; LMBR1-like membrane protein

    2. XM_009301180.4 → XP_009299455.1  G-protein coupled receptor-associated protein LMBRD2a isoform X1

      UniProtKB/TrEMBL
      A0A8M3B9B9
      Conserved Domains (1) summary
      pfam04791
      Location:14 → 550
      LMBR1; LMBR1-like membrane protein

    3. XM_068221170.1 → XP_068077271.1  G-protein coupled receptor-associated protein LMBRD2a isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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