man2c1 mannosidase, alpha, class 2C, member 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: man2c1provided by ZNC
Official Full Name: mannosidase, alpha, class 2C, member 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-101103-4
See related: Ensembl:ENSDARG00000079835 AllianceGenome:ZFIN:ZDB-GENE-101103-4
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable alpha-mannosidase activity. Predicted to be involved in oligosaccharide catabolic process. Predicted to act upstream of or within mannose metabolic process. Orthologous to human MAN2C1 (mannosidase alpha class 2C member 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	25	NC_007136.7 (26811898..26827048)
105	previous assembly	GRCz10 (GCF_000002035.5)	25	NC_007136.6 (26368683..26381128)

Chromosome 25 - NC_007136.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables alpha-mannosidase activity	IEA Inferred from Electronic Annotation more info
enables carbohydrate binding	IEA Inferred from Electronic Annotation more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, acting on glycosyl bonds	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mannose metabolic process	IEA Inferred from Electronic Annotation more info

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The following sections contain reference sequences that belong to a specific genome build. Explain

XM_009298093.4 → XP_009296368.1 alpha-mannosidase 2C1 isoform X1

UniProtKB/TrEMBL

A0A8M3B7A6

Conserved Domains (4) summary

cd10813
Location:263 → 513

GH38N_AMII_Man2C1; N-terminal catalytic domain of mammalian cytosolic alpha-mannosidase Man2C1 and similar proteins; glycoside hydrolase family 38 (GH38)

COG0383
Location:69 → 1031

AMS1; Alpha-mannosidase [Carbohydrate transport and metabolism]

pfam07748
Location:631 → 1029

Glyco_hydro_38C; Glycosyl hydrolases family 38 C-terminal domain

pfam09261
Location:527 → 606

Alpha-mann_mid; Alpha mannosidase, middle domain
XM_692992.8 → XP_698084.4 alpha-mannosidase 2C1 isoform X2

UniProtKB/TrEMBL

A0A8N7TBS0, X1WCE5

Related

ENSDARP00000127888.1, ENSDART00000157029.2

Conserved Domains (4) summary

cd10813
Location:253 → 503

GH38N_AMII_Man2C1; N-terminal catalytic domain of mammalian cytosolic alpha-mannosidase Man2C1 and similar proteins; glycoside hydrolase family 38 (GH38)

COG0383
Location:69 → 1021

AMS1; Alpha-mannosidase [Carbohydrate transport and metabolism]

pfam07748
Location:621 → 1019

Glyco_hydro_38C; Glycosyl hydrolases family 38 C-terminal domain

pfam09261
Location:517 → 596

Alpha-mann_mid; Alpha mannosidase, middle domain
XM_017354269.3 → XP_017209758.1 alpha-mannosidase 2C1 isoform X3

UniProtKB/TrEMBL

A0A8M6YW39