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    lmo4b LIM domain only 4b [ Danio rerio (zebrafish) ]

    Gene ID: 324849, updated on 2-Nov-2024

    Summary

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    Official Symbol
    lmo4bprovided by ZNC
    Official Full Name
    LIM domain only 4bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3570
    See related
    Ensembl:ENSDARG00000054749 AllianceGenome:ZFIN:ZDB-GENE-030131-3570
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    lmo4l; fc45c09; wu:fc45c09
    Summary
    Predicted to enable metal ion binding activity. Is expressed in several structures, including mesoderm; nervous system; optic vesicle; presumptive neural retina; and yolk syncytial layer. Orthologous to human LMO4 (LIM domain only 4). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See lmo4b in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (25933736..25952874, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (25943175..25962269, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene kynurenine--oxoglutarate transaminase 3 Neighboring gene kynurenine aminotransferase 3, tandem duplicate 2 Neighboring gene protein kinase N2b Neighboring gene uncharacterized LOC137495969 Neighboring gene heparan sulfate 2-O-sulfotransferase 1b Neighboring gene uncharacterized LOC137495970

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A zebrafish LMO4 ortholog limits the size of the forebrain and eyes through negative regulation of six3b and rx3. McCollum CW, et al. Dev Biol, 2007 Sep 15. PMID 17692837, Free PMC Article
    2. Cellular expression of Smarca4 (Brg1)-regulated genes in zebrafish retinas. Hensley MR, et al. BMC Dev Biol, 2011 Jul 14. PMID 21756345, Free PMC Article
    3. Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells. Monteiro R, et al. Dev Cell, 2016 Aug 22. PMID 27499523, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    LIM domain transcription factor LMO4b
    Names
    LIM domain only 4, like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212689.2 → NP_997854.2  LIM domain transcription factor LMO4b

      Status: VALIDATED

      Source sequence(s)
      CU019652
      UniProtKB/TrEMBL
      Q6DHC2, Q8JFQ1
      Related
      ENSDARP00000071465.4, ENSDART00000076997.6
      Conserved Domains (2) summary
      cd09386
      Location:23 → 77
      LIM1_LMO4; The first LIM domain of LMO4 (LIM domain only protein 4)
      cd09387
      Location:87 → 141
      LIM2_LMO4; The second LIM domain of LMO4 (LIM domain only protein 4)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      25933736..25952874 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394644.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      35161..54444 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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