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    ywhag2 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2 [ Danio rerio (zebrafish) ]

    Gene ID: 560560, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ywhag2provided by ZNC
    Official Full Name
    3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061023-2
    See related
    Ensembl:ENSDARG00000071658 AllianceGenome:ZFIN:ZDB-GENE-061023-2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ywhagl
    Summary
    Predicted to enable protein kinase C binding activity. Predicted to be involved in protein localization and signal transduction. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 56. Orthologous to human YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See ywhag2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (15349165..15357141, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (15412880..15421149, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene C2 domain containing 3 centriole elongation regulator Neighboring gene calcium/calmodulin-dependent protein kinase kinase 1, alpha b Neighboring gene si:ch211-105f12.2 Neighboring gene microRNA 142b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Expression analysis of the family of 14-3-3 proteins in zebrafish development. Besser J, et al. Gene Expr Patterns, 2007 Feb. PMID 17127101
    2. Comparative and evolutionary analysis of the 14-3-3 family genes in eleven fishes. Cao J, et al. Gene, 2018 Jul 1. PMID 29653226
    3. On the crucial cerebellar wound healing-related pathways and their cross-talks after traumatic brain injury in Danio rerio. Wu CC, et al. PLoS One, 2014. PMID 24926785, Free PMC Article
    4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables protein kinase C binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    14-3-3 protein gamma-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      15349165..15357141 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_683958.9 → XP_689050.2  14-3-3 protein gamma-1

      UniProtKB/TrEMBL
      A0A8M9PNI4, E7F354
      Related
      ENSDARP00000096898.3, ENSDART00000106120.5
      Conserved Domains (1) summary
      cd10024
      Location:2 → 247
      14-3-3_gamma; 14-3-3 gamma, an isoform of 14-3-3 protein

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394939.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      195763..203739 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021472913.2 → XP_021328588.1  14-3-3 protein gamma-1

      UniProtKB/TrEMBL
      A0A8M9PNI4, E7F354
      Conserved Domains (1) summary
      cd10024
      Location:2 → 247
      14-3-3_gamma; 14-3-3 gamma, an isoform of 14-3-3 protein
    Nucleotide Protein Strain
    Heading Accession and Version

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