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    slco1d1 solute carrier organic anion transporter family, member 1D1 [ Danio rerio (zebrafish) ]

    Gene ID: 326845, updated on 14-Nov-2024

    Summary

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    Official Symbol
    slco1d1provided by ZNC
    Official Full Name
    solute carrier organic anion transporter family, member 1D1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5044
    See related
    Ensembl:ENSDARG00000104108 AllianceGenome:ZFIN:ZDB-GENE-030131-5044
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    slco1c; wu:fe36b05; zgc:163027
    Summary
    Enables organic anion transmembrane transporter activity. Acts upstream of or within microcystin transport; organic anion transport; and transmembrane transport. Located in plasma membrane. Is expressed in several structures, including alar plate midbrain region; muscle; nervous system; optic vesicle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in bilirubin metabolic disorder and gastrointestinal stromal tumor. Orthologous to human SLCO1B1 (solute carrier organic anion transporter family member 1B1); SLCO1B3 (solute carrier organic anion transporter family member 1B3); and SLCO1B7 (solute carrier organic anion transporter family member 1B7 (putative)). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See slco1d1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (77389667..77432221, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (76004965..76047519, complement)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene NLR family CARD domain-containing protein 3-like Neighboring gene solute carrier organic anion transporter family, member 1F3 Neighboring gene solute carrier organic anion transporter family, member 1E1 Neighboring gene proton myo-inositol cotransporter Neighboring gene si:ch211-266c8.2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Zebrafish Oatp1d1 Acts as a Cellular Efflux Transporter of the Anionic Herbicide Bromoxynil. Halbach K, et al. Chem Res Toxicol, 2022 Feb 21. PMID 34990119
    2. Selective interaction of microcystin congeners with zebrafish (Danio rerio) Oatp1d1 transporter. Marić P, et al. Chemosphere, 2021 Nov. PMID 34182632
    3. Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide. Popovic M, et al. J Biol Chem, 2013 Nov 22. PMID 24126916, Free PMC Article
    4. Interaction of environmental steroids with organic anion transporting polypeptide (Oatp1d1) in zebrafish (Danio rerio). Willi RA, et al. Environ Toxicol Chem, 2018 Oct. PMID 30055005
    5. Interaction of environmental contaminants with zebrafish organic anion transporting polypeptide, Oatp1d1 (Slco1d1). Popovic M, et al. Toxicol Appl Pharmacol, 2014 Oct 1. PMID 25088042

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Zebrafish Oatp1d1 Acts as a Cellular Efflux Transporter of the Anionic Herbicide Bromoxynil.
      Title: Zebrafish Oatp1d1 Acts as a Cellular Efflux Transporter of the Anionic Herbicide Bromoxynil.
    2. Selective interaction of microcystin congeners with zebrafish (Danio rerio) Oatp1d1 transporter.
      Title: Selective interaction of microcystin congeners with zebrafish (Danio rerio) Oatp1d1 transporter.
    3. different classes of steroids interact with Oatp1d1 with different activity.
      Title: Interaction of environmental steroids with organic anion transporting polypeptide (Oatp1d1) in zebrafish (Danio rerio).
    4. Zebrafish Oatp1d1 offers new insights into the uptake processes of environmental contaminants.
      Title: Interaction of environmental contaminants with zebrafish organic anion transporting polypeptide, Oatp1d1 (Slco1d1).
    5. detailed characterization of a new Oatp transporter in zebrafish, offering important insights into the functional evolution of the OATP1/Oatp1 family and the physiological role of Oatp1d1.
      Title: Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables organic anion transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within microcystin transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within organic anion transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    solute carrier organic anion transporter family, member 1D1
    Names
    Oatp1d1
    solute carrier anion transporting family member 1d1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001348086.1 → NP_001335015.1  solute carrier organic anion transporter family, member 1D1

      Status: VALIDATED

      Source sequence(s)
      FP236807
      UniProtKB/TrEMBL
      A0A8M9PU70
      Related
      ENSDARP00000139849.2, ENSDART00000158683.3
      Conserved Domains (1) summary
      pfam03137
      Location:16 → 617
      OATP; Organic Anion Transporter Polypeptide (OATP) family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      77389667..77432221 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001089333.1: Suppressed sequence

      Description
      NM_001089333.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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