U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    laptm4b lysosomal protein transmembrane 4 beta [ Danio rerio (zebrafish) ]

    Gene ID: 368911, updated on 2-Nov-2024

    Summary

    Official Symbol
    laptm4bprovided by ZNC
    Official Full Name
    lysosomal protein transmembrane 4 betaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030616-616
    See related
    Ensembl:ENSDARG00000035870 AllianceGenome:ZFIN:ZDB-GENE-030616-616
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fd60g10; zgc:73120; wu:fd60g10; si:zc215i13.7
    Summary
    Predicted to be located in several cellular components, including lysosome; multivesicular body membrane; and plasma membrane. Predicted to be active in lysosomal membrane. Is expressed in epiphysis; otic placode; otic vesicle; and retina. Orthologous to human LAPTM4B (lysosomal protein transmembrane 4 beta). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See laptm4b in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (32864577..32888758, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (33277457..33301638, complement)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488533 Neighboring gene ribosomal protein L30 Neighboring gene metadherin a Neighboring gene ribonucleotide reductase M2 b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in lysosomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in multivesicular body membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    lysosomal-associated transmembrane protein 4B
    Names
    lysosomal associated protein transmembrane 4 beta

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200098.2NP_956392.1  lysosomal-associated transmembrane protein 4B

      See identical proteins and their annotated locations for NP_956392.1

      Status: VALIDATED

      Source sequence(s)
      AL807244, EH440716
      UniProtKB/TrEMBL
      Q6PC39, Q801V1
      Related
      ENSDARP00000052079.3, ENSDART00000052080.4
      Conserved Domains (1) summary
      cl04276
      Location:6225
      Mtp; Golgi 4-transmembrane spanning transporter

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      32864577..32888758 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395056.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      1227..25408 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)