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    Iqck IQ motif containing K [ Mus musculus (house mouse) ]

    Gene ID: 434232, updated on 9-Aug-2024

    Summary

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    Official Symbol
    Iqckprovided by MGI
    Official Full Name
    IQ motif containing Kprovided by MGI
    Primary source
    MGI:MGI:3612188
    See related
    Ensembl:ENSMUSG00000073856 AllianceGenome:MGI:3612188
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A230094G09Rik
    Summary
    Orthologous to human IQCK (IQ motif containing K). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in testis adult (RPKM 5.8), cerebellum adult (RPKM 4.2) and 15 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Iqck in Genome Data Viewer
    Location:
    7 F2; 7 63.67 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (118454975..118571343)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (118855752..118972120)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene VPS35 endosomal protein sorting factor like Neighboring gene STARR-seq mESC enhancer starr_20027 Neighboring gene predicted gene, 26147 Neighboring gene lysine rich nucleolar protein 1 Neighboring gene STARR-seq mESC enhancer starr_20029 Neighboring gene G protein-coupled receptor, family C, group 5, member B Neighboring gene predicted gene, 39076 Neighboring gene G protein-coupled receptor 139

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    IQ domain-containing protein K

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081446.2 → NP_001074915.1  IQ domain-containing protein K isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC138717, AC151534
      Consensus CDS
      CCDS40105.1
      UniProtKB/TrEMBL
      E9PUC1
      Related
      ENSMUSP00000102157.2, ENSMUST00000106547.2
      Conserved Domains (1) summary
      smart00015
      Location:217 → 235
      IQ; Calmodulin-binding motif

    2. NM_001374605.1 → NP_001361534.1  IQ domain-containing protein K isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC138717, AC151534
      Consensus CDS
      CCDS90320.1
      UniProtKB/TrEMBL
      D3YYL3
      Related
      ENSMUSP00000095693.3, ENSMUST00000098087.9
      Conserved Domains (1) summary
      smart00015
      Location:220 → 238
      IQ; Calmodulin-binding motif

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      118454975..118571343
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006507984.5 → XP_006508047.1  IQ domain-containing protein K isoform X3

    2. XM_017322337.3 → XP_017177826.1  IQ domain-containing protein K isoform X4

    3. XM_006507983.5 → XP_006508046.1  IQ domain-containing protein K isoform X2

    4. XM_006507982.5 → XP_006508045.1  IQ domain-containing protein K isoform X1

    RNA

    1. XR_003946504.2 RNA Sequence

    2. XR_378252.5 RNA Sequence

      Related
      ENSMUST00000152136.8

    3. XR_004934129.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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