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    Meioc meiosis specific with coiled-coil domain [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303572, updated on 17-Aug-2024

    Summary

    Official Symbol
    Meiocprovided by RGD
    Official Full Name
    meiosis specific with coiled-coil domainprovided by RGD
    Primary source
    RGD:1563746
    See related
    EnsemblRapid:ENSRNOG00000021953 AllianceGenome:RGD:1563746
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563746
    Summary
    Predicted to be involved in several processes, including gamete generation; germline cell cycle switching, mitotic to meiotic cell cycle; and synaptonemal complex assembly. Predicted to be active in cytoplasm and nucleus. Orthologous to human MEIOC (meiosis specific with coiled-coil domain). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward (RPKM 171.4) See more
    Orthologs
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    Genomic context

    See Meioc in Genome Data Viewer
    Location:
    10q32.1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (88128939..88147833)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (87628807..87646485)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (90622954..90641883)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene ATPase H+ transporting V0 subunit C, pseudogene 1 Neighboring gene frizzled class receptor 2 Neighboring gene coiled-coil domain containing 43 Neighboring gene uncharacterized LOC120095185 Neighboring gene uncharacterized LOC103693436

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in chromosome organization involved in meiotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in double-strand break repair ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in female meiosis I IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in female meiosis I ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in germline cell cycle switching, mitotic to meiotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA stabilization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mRNA stabilization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in male meiosis I IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in male meiosis I ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in metaphase chromosome alignment ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in oocyte development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spermatid development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in synaptonemal complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    meiosis-specific coiled-coil domain-containing protein MEIOC

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      88128939..88147833
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063270158.1XP_063126228.1  meiosis-specific coiled-coil domain-containing protein MEIOC isoform X2

      UniProtKB/TrEMBL
      A0A8I6GJR6
    2. XM_220997.11XP_220997.5  meiosis-specific coiled-coil domain-containing protein MEIOC isoform X1

      See identical proteins and their annotated locations for XP_220997.5

      UniProtKB/TrEMBL
      A0A8I6GJR6, D4A1P7
      Related
      ENSRNOP00000038645.6, ENSRNOT00000032856.8
      Conserved Domains (1) summary
      pfam15189
      Location:752917
      DUF4582; Domain of unknown function (DUF4582)