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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_032778.1 RefSeqGene
- Range
-
5039..44340
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_1330
mRNA and Protein(s)
-
NM_001257970.1 → NP_001244899.1 caspase recruitment domain-containing protein 14 isoform 3
See identical proteins and their annotated locations for NP_001244899.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks several exons and its transcription extends past a splice site that is used in variant 1. The encoded isoform 3 has a shorter C-terminus, compared to isoform 1.
- Source sequence(s)
-
AC087741, BC018142
- Consensus CDS
-
CCDS58605.1
- UniProtKB/TrEMBL
-
A0A494C199
- Related
- ENSP00000461806.1, ENST00000570421.5
- Conserved Domains (5) summary
-
- cd00992
Location:583 → 655
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd08806
Location:19 → 104
- CARD_CARD14_CARMA2; Caspase activation and recruitment domain of CARD14-like proteins
- pfam15252
Location:410 → 481
- DUF4589; Domain of unknown function (DUF4589)
- cl17036
Location:680 → 740
- SH3; Src Homology 3 domain superfamily
- cl25732
Location:151 → 409
- SMC_N; RecF/RecN/SMC N terminal domain
-
NM_001366385.1 → NP_001353314.1 caspase recruitment domain-containing protein 14 isoform 1
Status: REVIEWED
- Source sequence(s)
-
AC087741
- Consensus CDS
-
CCDS11768.1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
- Related
- ENSP00000498071.1, ENST00000648509.2
- Conserved Domains (5) summary
-
- cd00992
Location:583 → 655
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd08806
Location:19 → 104
- CARD_CARD14_CARMA2; Caspase activation and recruitment domain of CARD14-like proteins
- cl17036
Location:680 → 742
- SH3; Src Homology 3 domain superfamily
- cl17190
Location:858 → 961
- NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
- cl25732
Location:151 → 448
- SMC_N; RecF/RecN/SMC N terminal domain
-
NM_024110.4 → NP_077015.2 caspase recruitment domain-containing protein 14 isoform 1
See identical proteins and their annotated locations for NP_077015.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1). Variants 1 and 5 encode the same isoform.
- Source sequence(s)
-
AC087741, AF322642, BU617627
- Consensus CDS
-
CCDS11768.1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
- Related
- ENSP00000344549.2, ENST00000344227.6
- Conserved Domains (5) summary
-
- cd00992
Location:583 → 655
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd08806
Location:19 → 104
- CARD_CARD14_CARMA2; Caspase activation and recruitment domain of CARD14-like proteins
- cl17036
Location:680 → 742
- SH3; Src Homology 3 domain superfamily
- cl17190
Location:858 → 961
- NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
- cl25732
Location:151 → 448
- SMC_N; RecF/RecN/SMC N terminal domain
-
NM_052819.3 → NP_438170.1 caspase recruitment domain-containing protein 14 isoform 2
See identical proteins and their annotated locations for NP_438170.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks several exons at the 5' and 3' ends and its transcription extends past a splice site that is used in variant 1. The encoded isoform 2 has a shorter N-terminus and a distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AC087741, BC001326
- UniProtKB/TrEMBL
-
B4DKY0
- Related
-
ENST00000573754.5
- Conserved Domains (2) summary
-
- COG1196
Location:8 → 211
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00992
Location:346 → 381
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
RNA
-
NR_047566.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) uses an alternate splice site in an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC087741, AK091123, BU617627, DA461380
- Related
-
ENST00000575500.5
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000017.11 Reference GRCh38.p14 Primary Assembly
- Range
-
80170030..80209331
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047436713.1 → XP_047292669.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
- Related
- ENSP00000499145.1, ENST00000651672.1
-
XM_047436719.1 → XP_047292675.1 caspase recruitment domain-containing protein 14 isoform X3
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_047436714.1 → XP_047292670.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_011525213.2 → XP_011523515.1 caspase recruitment domain-containing protein 14 isoform X1
See identical proteins and their annotated locations for XP_011523515.1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
- Conserved Domains (5) summary
-
- cd00992
Location:583 → 655
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd08806
Location:19 → 104
- CARD_CARD14_CARMA2; Caspase activation and recruitment domain of CARD14-like proteins
- cl17036
Location:680 → 742
- SH3; Src Homology 3 domain superfamily
- cl17190
Location:858 → 961
- NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
- cl25732
Location:151 → 448
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_011525216.2 → XP_011523518.1 caspase recruitment domain-containing protein 14 isoform X1
See identical proteins and their annotated locations for XP_011523518.1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
- Conserved Domains (5) summary
-
- cd00992
Location:583 → 655
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd08806
Location:19 → 104
- CARD_CARD14_CARMA2; Caspase activation and recruitment domain of CARD14-like proteins
- cl17036
Location:680 → 742
- SH3; Src Homology 3 domain superfamily
- cl17190
Location:858 → 961
- NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
- cl25732
Location:151 → 448
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_011525218.2 → XP_011523520.1 caspase recruitment domain-containing protein 14 isoform X1
See identical proteins and their annotated locations for XP_011523520.1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
- Conserved Domains (5) summary
-
- cd00992
Location:583 → 655
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd08806
Location:19 → 104
- CARD_CARD14_CARMA2; Caspase activation and recruitment domain of CARD14-like proteins
- cl17036
Location:680 → 742
- SH3; Src Homology 3 domain superfamily
- cl17190
Location:858 → 961
- NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
- cl25732
Location:151 → 448
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_047436715.1 → XP_047292671.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
- Related
- ENSP00000458715.1, ENST00000573882.5
-
XM_047436717.1 → XP_047292673.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_047436716.1 → XP_047292672.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_047436718.1 → XP_047292674.1 caspase recruitment domain-containing protein 14 isoform X2
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_047436720.1 → XP_047292676.1 caspase recruitment domain-containing protein 14 isoform X4
- UniProtKB/TrEMBL
-
A0A494C0J4
- Related
- ENSP00000498570.1, ENST00000650867.1
-
XM_047436721.1 → XP_047292677.1 caspase recruitment domain-containing protein 14 isoform X5
- UniProtKB/TrEMBL
-
A0A494C199
-
XM_047436722.1 → XP_047292678.1 caspase recruitment domain-containing protein 14 isoform X6
- UniProtKB/TrEMBL
- A0A494C199, A0A994J6G4
- Related
- ENSP00000515382.1, ENST00000703566.1
-
XM_047436723.1 → XP_047292679.1 caspase recruitment domain-containing protein 14 isoform X7
- UniProtKB/TrEMBL
-
A0A494BZY0
- Related
- ENSP00000498274.1, ENST00000651068.1
Reference GRCh38.p14 PATCHES
Genomic
-
NW_025791802.1 Reference GRCh38.p14 PATCHES
- Range
-
194698..234037
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054333205.1 → XP_054189180.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054333202.1 → XP_054189177.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054333204.1 → XP_054189179.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054333200.1 → XP_054189175.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054333209.1 → XP_054189184.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054333208.1 → XP_054189183.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054333201.1 → XP_054189176.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054333206.1 → XP_054189181.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054333203.1 → XP_054189178.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/Swiss-Prot
- B8QQJ3, Q9BVB5, Q9BXL6
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054333207.1 → XP_054189182.1 caspase recruitment domain-containing protein 14 isoform X2
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054333210.1 → XP_054189185.1 caspase recruitment domain-containing protein 14 isoform X4
- UniProtKB/TrEMBL
-
A0A494C0J4
-
XM_054333211.1 → XP_054189186.1 caspase recruitment domain-containing protein 14 isoform X5
- UniProtKB/TrEMBL
-
A0A494C199
-
XM_054333212.1 → XP_054189187.1 caspase recruitment domain-containing protein 14 isoform X6
- UniProtKB/TrEMBL
- A0A494C199, A0A994J6G4
-
XM_054333213.1 → XP_054189188.1 caspase recruitment domain-containing protein 14 isoform X7
- UniProtKB/TrEMBL
-
A0A494BZY0
Alternate T2T-CHM13v2.0
Genomic
-
NC_060941.1 Alternate T2T-CHM13v2.0
- Range
-
81070412..81109756
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054317155.1 → XP_054173130.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054317152.1 → XP_054173127.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054317154.1 → XP_054173129.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054317150.1 → XP_054173125.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054317159.1 → XP_054173134.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054317158.1 → XP_054173133.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054317151.1 → XP_054173126.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054317156.1 → XP_054173131.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054317153.1 → XP_054173128.1 caspase recruitment domain-containing protein 14 isoform X1
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054317157.1 → XP_054173132.1 caspase recruitment domain-containing protein 14 isoform X2
- UniProtKB/TrEMBL
-
A0A494C1N2
-
XM_054317160.1 → XP_054173135.1 caspase recruitment domain-containing protein 14 isoform X4
-
XM_054317161.1 → XP_054173136.1 caspase recruitment domain-containing protein 14 isoform X5
- UniProtKB/TrEMBL
-
A0A494C199
-
XM_054317162.1 → XP_054173137.1 caspase recruitment domain-containing protein 14 isoform X6
- UniProtKB/TrEMBL
-
A0A494C199
-
XM_054317163.1 → XP_054173138.1 caspase recruitment domain-containing protein 14 isoform X7
- UniProtKB/TrEMBL
-
A0A494BZY0