pex13 peroxisomal biogenesis factor 13 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pex13provided by ZNC
Official Full Name: peroxisomal biogenesis factor 13provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1544
See related: Ensembl:ENSDARG00000071037 AllianceGenome:ZFIN:ZDB-GENE-040426-1544
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:66124
Summary: Predicted to be involved in protein import into peroxisome matrix, docking. Predicted to act upstream of or within protein transport. Predicted to be located in membrane and peroxisome. Predicted to be part of peroxisomal importomer complex. Predicted to be active in peroxisomal membrane. Human ortholog(s) of this gene implicated in Peroxisome biogenesis disorder 11B and peroxisome biogenesis disorder 11A. Orthologous to human PEX13 (peroxisomal biogenesis factor 13). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (23926796..23935450)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (23908395..23917049)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

PEX13 prevents pexophagy by regulating ubiquitinated PEX5 and peroxisomal ROS.
Title: PEX13 prevents pexophagy by regulating ubiquitinated PEX5 and peroxisomal ROS.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in protein import into peroxisome matrix, docking	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein import into peroxisome matrix, docking	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of peroxisomal importomer complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in peroxisomal membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in peroxisome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: peroxisome biogenesis factor 13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200645.1 → NP_956939.1 peroxisome biogenesis factor 13

See identical proteins and their annotated locations for NP_956939.1

Status: PROVISIONAL

Source sequence(s)

BC057464

UniProtKB/TrEMBL

A0A8M1PES8, Q6PFQ3

Related

ENSDARP00000009932.7, ENSDART00000021177.8

Conserved Domains (2) summary

cd11864
Location:278 → 335

SH3_PEX13_eumet; Src Homology 3 domain of eumetazoan Peroxisomal biogenesis factor 13

pfam04088
Location:108 → 256

Peroxin-13_N; Peroxin 13, N-terminal region