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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_012742.3 RefSeqGene
- Range
-
5002..697958
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001024660.5 → NP_001019831.2 kalirin isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). There are no publicly available transcripts representing the full-length splicing pattern of this variant; it is inferred from data in PMID:11891045 and from the rat homolog, NM_032062.1.
- Source sequence(s)
-
AB011422, AC022336, AK125979, AK131379, AK314126, BM930007, BQ345377, DA756158, H11479, R45191, U94190
- UniProtKB/Swiss-Prot
- A8MSI4, C9JQ37, J3QSW6, O60229, Q6ZN45, Q8TBQ5, Q9NSZ4, Q9Y2A5
- UniProtKB/TrEMBL
-
H7BXZ5
- Related
- ENSP00000353109.3, ENST00000360013.7
- Conserved Domains (13) summary
-
- smart00150
Location:1135 → 1235
- SPEC; Spectrin repeats
- cd11852
Location:1649 → 1708
- SH3_Kalirin_1; First Src homology 3 domain of the RhoGEF kinase, Kalirin
- cd11853
Location:2325 → 2383
- SH3_Kalirin_2; Second Src homology 3 domain of the RhoGEF kinase, Kalirin
- smart00516
Location:39 → 177
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00063
Location:2569 → 2660
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd00160
Location:1284 → 1454
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:891 → 1129
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd13240
Location:1461 → 1583
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- cd13241
Location:2107 → 2241
- PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
- cd14115
Location:2690 → 2937
- STKc_Kalirin_C; C-terminal kinase domain of the Large Serine/Threonine Kinase and Rho Guanine Nucleotide Exchange Factor, Kalirin
- pfam00621
Location:1933 → 2102
- RhoGEF; RhoGEF domain
- pfam07679
Location:2471 → 2565
- I-set; Immunoglobulin I-set domain
- pfam16609
Location:1706 → 1923
- SH3-RhoG_link; SH3-RhoGEF linking unstructured region
-
NM_001322988.2 → NP_001309917.1 kalirin isoform 4
Status: REVIEWED
- Source sequence(s)
-
AC069233, AC080008, AC112129, AC117401, AL137629
- UniProtKB/TrEMBL
-
A0A1S5UZ29
-
NM_001322989.2 → NP_001309918.1 kalirin isoform 5
Status: REVIEWED
- Source sequence(s)
-
AC069233, AC112129, AI024603, AK314126, U94190
- Consensus CDS
-
CCDS82829.1
- UniProtKB/TrEMBL
-
C9IZQ6
- Related
- ENSP00000418611.1, ENST00000460856.5
- Conserved Domains (6) summary
-
- smart00150
Location:1126 → 1226
- SPEC; Spectrin repeats
- smart00516
Location:39 → 177
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:1275 → 1445
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:891 → 1120
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd13240
Location:1452 → 1574
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- pfam00169
Location:1485 → 1570
- PH; PH domain
-
NM_001322990.2 → NP_001309919.1 kalirin isoform 6
Status: REVIEWED
- Source sequence(s)
-
AC069233, AC080008, AC112129, AC117401, AI024603
-
NM_001322991.2 → NP_001309920.1 kalirin isoform 7
Status: REVIEWED
- Source sequence(s)
-
AC069233, AC080008, AC112129, AC117401, AI024603
-
NM_001322992.2 → NP_001309921.1 kalirin isoform 8
Status: REVIEWED
- Source sequence(s)
-
AC069233, AC080008, AC112129, AC117401, AI024603
- Consensus CDS
-
CCDS93360.1
- UniProtKB/TrEMBL
-
A0A804HKT9
- Related
- ENSP00000508068.1, ENST00000684276.1
-
NM_001322993.2 → NP_001309922.1 kalirin isoform 9
Status: REVIEWED
- Source sequence(s)
-
AC022336, AC080008, H11479
-
NM_001322994.2 → NP_001309923.1 kalirin isoform 10
Status: REVIEWED
- Source sequence(s)
-
AC080008, AL137629
- Consensus CDS
-
CCDS93363.1
- UniProtKB/TrEMBL
-
A0A804HKJ7
- Related
- ENSP00000507954.1, ENST00000682363.1
-
NM_001322995.2 → NP_001309924.1 kalirin isoform 11
Status: REVIEWED
- Source sequence(s)
-
AC080008, AL137629
- UniProtKB/Swiss-Prot
-
O60229
-
NM_001322996.2 → NP_001309925.1 kalirin isoform 12
Status: REVIEWED
- Source sequence(s)
-
AC080008, AL137629
- UniProtKB/Swiss-Prot
-
O60229
- Conserved Domains (5) summary
-
- cd11853
Location:627 → 685
- SH3_Kalirin_2; Second Src homology 3 domain of the RhoGEF kinase, Kalirin
- cd13241
Location:410 → 544
- PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
- pfam00169
Location:443 → 529
- PH; PH domain
- pfam00621
Location:236 → 406
- RhoGEF; RhoGEF domain
- pfam16609
Location:25 → 235
- SH3-RhoG_link; SH3-RhoGEF linking unstructured region
-
NM_001322997.2 → NP_001309926.1 kalirin isoform 13
Status: REVIEWED
- Source sequence(s)
-
AC080008, AL137629
- UniProtKB/Swiss-Prot
-
O60229
-
NM_001322998.2 → NP_001309927.1 kalirin isoform 14
Status: REVIEWED
- Source sequence(s)
-
AC080008, AL137629
- UniProtKB/Swiss-Prot
-
O60229
-
NM_001322999.2 → NP_001309928.1 kalirin isoform 15
Status: REVIEWED
- Description
- Transcript Variant: Variants 16 and 17 encode isoforms that are the same length, but have distinct protein sequences.
- Source sequence(s)
-
AC080008, AL137629
- UniProtKB/Swiss-Prot
-
O60229
-
NM_001323000.2 → NP_001309929.1 kalirin isoform 16
Status: REVIEWED
- Description
- Transcript Variant: Variants 16 and 17 encode isoforms that are the same length, but have distinct protein sequences.
- Source sequence(s)
-
AC080008, AL137629
- UniProtKB/Swiss-Prot
-
O60229
-
NM_001323001.2 → NP_001309930.1 kalirin isoform 17
Status: REVIEWED
- Source sequence(s)
-
AC080008, AL137629
- UniProtKB/Swiss-Prot
-
O60229
-
NM_001388412.1 → NP_001375341.1 kalirin isoform 18
Status: REVIEWED
- Source sequence(s)
-
AC069233, AC080008
- Conserved Domains (10) summary
-
- smart00150
Location:494 → 594
- SPEC; Spectrin repeats
- cd11852
Location:1008 → 1067
- SH3_Kalirin_1; First Src homology 3 domain of the RhoGEF kinase, Kalirin
- cd11853
Location:1683 → 1741
- SH3_Kalirin_2; Second Src homology 3 domain of the RhoGEF kinase, Kalirin
- cd00160
Location:643 → 813
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:250 → 488
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd13240
Location:820 → 942
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- cd13241
Location:1466 → 1600
- PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
- pfam00621
Location:1292 → 1461
- RhoGEF; RhoGEF domain
- pfam16609
Location:1065 → 1291
- SH3-RhoG_link; SH3-RhoGEF linking unstructured region
- cl02488
Location:5 → 249
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
NM_001388413.1 → NP_001375342.1 kalirin isoform 19
Status: REVIEWED
- Source sequence(s)
-
AC069233, AC080008
- Consensus CDS
-
CCDS93362.1
- UniProtKB/TrEMBL
- A0A804HI91, A0A804HJC5
- Related
- ENSP00000506956.1, ENST00000682695.1
- Conserved Domains (5) summary
-
- smart00150
Location:494 → 594
- SPEC; Spectrin repeats
- cd00160
Location:643 → 813
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:250 → 488
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd13240
Location:820 → 942
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- cl02488
Location:5 → 249
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
NM_001388414.1 → NP_001375343.1 kalirin isoform 20
Status: REVIEWED
- Source sequence(s)
-
AC069233, AC080008
- UniProtKB/TrEMBL
-
A0A804HJC5
- Related
- ENSP00000507281.1, ENST00000683356.1
-
NM_001388415.1 → NP_001375344.1 kalirin isoform 21
Status: REVIEWED
- Source sequence(s)
-
AC069233, AC080008
- UniProtKB/TrEMBL
-
A0A804HJC5
- Related
- ENSP00000507171.1, ENST00000683146.1
- Conserved Domains (5) summary
-
- smart00150
Location:481 → 581
- SPEC; Spectrin repeats
- cd00160
Location:630 → 800
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:237 → 475
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd13240
Location:807 → 929
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- cl02488
Location:5 → 236
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
NM_001388416.1 → NP_001375345.1 kalirin isoform 22
Status: REVIEWED
- Source sequence(s)
-
AC069233, AC080008
- Consensus CDS
-
CCDS93361.1
- UniProtKB/TrEMBL
- A0A804HIN3, A0A804HJC5
- Related
- ENSP00000507150.1, ENST00000684382.1
- Conserved Domains (4) summary
-
- smart00150
Location:472 → 572
- SPEC; Spectrin repeats
- cd00160
Location:621 → 791
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:237 → 466
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd13240
Location:798 → 920
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
-
NM_001388417.1 → NP_001375346.1 kalirin isoform 23
Status: REVIEWED
- Source sequence(s)
-
AC069233, AC080008, AC112129, AC117381, AC117401
- Conserved Domains (6) summary
-
- smart00150
Location:1137 → 1237
- SPEC; Spectrin repeats
- smart00516
Location:41 → 179
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:1286 → 1456
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:539 → 720
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd13240
Location:1463 → 1585
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- TIGR02168
Location:745 → 1029
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
-
NM_001388418.1 → NP_001375347.1 kalirin isoform 24
Status: REVIEWED
- Source sequence(s)
-
AC069233, AC080008, AC112129, AC117381, AC117401
- Conserved Domains (5) summary
-
- smart00150
Location:1128 → 1228
- SPEC; Spectrin repeats
- smart00516
Location:41 → 179
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:1277 → 1447
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:893 → 1122
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd13240
Location:1454 → 1576
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
-
NM_001388419.1 → NP_001375348.1 kalirin isoform 25
Status: REVIEWED
- Source sequence(s)
-
AC022336, AC069233, AC080008, AC112129, AC117381, AC117401
- Consensus CDS
-
CCDS93359.1
- UniProtKB/TrEMBL
- A0A804HLI0, H7BXZ5
- Related
- ENSP00000508359.1, ENST00000682506.1
- Conserved Domains (14) summary
-
- smart00150
Location:1137 → 1237
- SPEC; Spectrin repeats
- cd11852
Location:1651 → 1710
- SH3_Kalirin_1; First Src homology 3 domain of the RhoGEF kinase, Kalirin
- cd11853
Location:2325 → 2383
- SH3_Kalirin_2; Second Src homology 3 domain of the RhoGEF kinase, Kalirin
- smart00516
Location:41 → 179
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00063
Location:2569 → 2660
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd00160
Location:1286 → 1456
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:893 → 1131
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd13240
Location:1463 → 1585
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- cd13241
Location:2108 → 2242
- PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
- cd14115
Location:2690 → 2937
- STKc_Kalirin_C; C-terminal kinase domain of the Large Serine/Threonine Kinase and Rho Guanine Nucleotide Exchange Factor, Kalirin
- pfam00621
Location:1934 → 2103
- RhoGEF; RhoGEF domain
- pfam07679
Location:2471 → 2565
- I-set; Immunoglobulin I-set domain
- pfam16609
Location:1708 → 1933
- SH3-RhoG_link; SH3-RhoGEF linking unstructured region
- cd00096
Location:2463 → 2466
- Ig; Ig strand A [structural motif]
-
NM_003947.6 → NP_003938.1 kalirin isoform 2
See identical proteins and their annotated locations for NP_003938.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 3' UTR and lacks many exons in the 3' coding region, compared to variant 1. The encoded protein (isoform 2), also known as Trad and Duet, is shorter and has a distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AI024603, AK131379, AK314126, BQ345377, U94190
- Consensus CDS
-
CCDS3027.1
- UniProtKB/Swiss-Prot
-
O60229
- Related
- ENSP00000240874.3, ENST00000240874.7
- Conserved Domains (6) summary
-
- smart00150
Location:1135 → 1235
- SPEC; Spectrin repeats
- smart00516
Location:39 → 177
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:1284 → 1454
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:537 → 718
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd13240
Location:1461 → 1583
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- TIGR02168
Location:743 → 1027
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
-
NM_007064.5 → NP_008995.2 kalirin isoform 3
See identical proteins and their annotated locations for NP_008995.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR and lacks many exons in the 5' coding region, compared to variant 1. The encoded protein (isoform 3), also known as Duo, is shorter and has a distinct N-terminus, compared to isoform 1.
- Source sequence(s)
-
AB011422, AC022336, AC080008, AK125979, BM930007, DA756158, DB450617, H11479, R45191
- Consensus CDS
-
CCDS3028.1
- UniProtKB/Swiss-Prot
-
O60229
- Related
- ENSP00000291478.4, ENST00000291478.9
- Conserved Domains (9) summary
-
- cd00096
Location:791 → 865
- Ig; Immunoglobulin domain
- cd11853
Location:628 → 686
- SH3_Kalirin_2; Second Src homology 3 domain of the RhoGEF kinase, Kalirin
- smart00220
Location:987 → 1241
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd00063
Location:872 → 963
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam07679
Location:774 → 868
- I-set; Immunoglobulin I-set domain
- cd13241
Location:410 → 544
- PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
- cd14115
Location:993 → 1240
- STKc_Kalirin_C; C-terminal kinase domain of the Large Serine/Threonine Kinase and Rho Guanine Nucleotide Exchange Factor, Kalirin
- pfam00621
Location:236 → 406
- RhoGEF; RhoGEF domain
- pfam16609
Location:25 → 235
- SH3-RhoG_link; SH3-RhoGEF linking unstructured region
RNA
-
NR_028136.3 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) includes the same 5' exon but differs in the remaining exons, compared to variant 1. This variant is represented as non-coding because the use of the supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AK128223, AK311154, AK314126, BC037924
- Related
-
ENST00000682890.1
-
NR_170952.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC069233, AC080008
-
NR_170953.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC069233, AC080008
- Related
-
ENST00000682277.1
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000003.12 Reference GRCh38.p14 Primary Assembly
- Range
-
124033369..124726325
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_006713810.4 → XP_006713873.1 kalirin isoform X1
- UniProtKB/TrEMBL
-
H7BXZ5
- Conserved Domains (16) summary
-
- cd00096
Location:2490 → 2564
- Ig; Immunoglobulin domain
- cd11852
Location:1651 → 1710
- SH3_Kalirin_1; First Src homology 3 domain of the RhoGEF kinase, Kalirin
- cd11853
Location:2327 → 2385
- SH3_Kalirin_2; Second Src homology 3 domain of the RhoGEF kinase, Kalirin
- smart00220
Location:2686 → 2940
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- smart00516
Location:41 → 179
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00063
Location:2571 → 2662
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd00160
Location:1286 → 1456
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:893 → 1131
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam07679
Location:2473 → 2567
- I-set; Immunoglobulin I-set domain
- cd13240
Location:1463 → 1585
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- cd13241
Location:2109 → 2243
- PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
- cd14115
Location:2692 → 2939
- STKc_Kalirin_C; C-terminal kinase domain of the Large Serine/Threonine Kinase and Rho Guanine Nucleotide Exchange Factor, Kalirin
- pfam00169
Location:1496 → 1581
- PH; PH domain
- pfam00621
Location:1935 → 2105
- RhoGEF; RhoGEF domain
- pfam16609
Location:1708 → 1934
- SH3-RhoG_link; SH3-RhoGEF linking unstructured region
- cl02488
Location:1101 → 1240
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_017007429.2 → XP_016862918.1 kalirin isoform X7
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_011513279.3 → XP_011511581.1 kalirin isoform X2
- UniProtKB/TrEMBL
-
H7BXZ5
- Conserved Domains (16) summary
-
- cd00096
Location:2489 → 2563
- Ig; Immunoglobulin domain
- cd11852
Location:1651 → 1710
- SH3_Kalirin_1; First Src homology 3 domain of the RhoGEF kinase, Kalirin
- cd11853
Location:2326 → 2384
- SH3_Kalirin_2; Second Src homology 3 domain of the RhoGEF kinase, Kalirin
- smart00220
Location:2685 → 2939
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- smart00516
Location:41 → 179
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00063
Location:2570 → 2661
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd00160
Location:1286 → 1456
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:893 → 1131
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam07679
Location:2472 → 2566
- I-set; Immunoglobulin I-set domain
- cd13240
Location:1463 → 1585
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- cd13241
Location:2109 → 2243
- PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
- cd14115
Location:2691 → 2938
- STKc_Kalirin_C; C-terminal kinase domain of the Large Serine/Threonine Kinase and Rho Guanine Nucleotide Exchange Factor, Kalirin
- pfam00169
Location:1496 → 1581
- PH; PH domain
- pfam00621
Location:1935 → 2105
- RhoGEF; RhoGEF domain
- pfam16609
Location:1708 → 1934
- SH3-RhoG_link; SH3-RhoGEF linking unstructured region
- cl02488
Location:1101 → 1240
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047449157.1 → XP_047305113.1 kalirin isoform X8
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_006713814.4 → XP_006713877.1 kalirin isoform X10
- UniProtKB/TrEMBL
-
H7BXZ5
- Conserved Domains (16) summary
-
- cd00096
Location:2458 → 2532
- Ig; Immunoglobulin domain
- cd11852
Location:1651 → 1710
- SH3_Kalirin_1; First Src homology 3 domain of the RhoGEF kinase, Kalirin
- cd11853
Location:2295 → 2353
- SH3_Kalirin_2; Second Src homology 3 domain of the RhoGEF kinase, Kalirin
- smart00220
Location:2654 → 2908
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- smart00516
Location:41 → 179
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00063
Location:2539 → 2630
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd00160
Location:1286 → 1456
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:893 → 1131
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam07679
Location:2441 → 2535
- I-set; Immunoglobulin I-set domain
- cd13240
Location:1463 → 1585
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- cd13241
Location:2077 → 2211
- PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
- cd14115
Location:2660 → 2907
- STKc_Kalirin_C; C-terminal kinase domain of the Large Serine/Threonine Kinase and Rho Guanine Nucleotide Exchange Factor, Kalirin
- pfam00169
Location:1496 → 1581
- PH; PH domain
- pfam00621
Location:1903 → 2073
- RhoGEF; RhoGEF domain
- pfam16609
Location:1708 → 1865
- SH3-RhoG_link; SH3-RhoGEF linking unstructured region
- cl02488
Location:1101 → 1240
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047449158.1 → XP_047305114.1 kalirin isoform X11
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_011513280.3 → XP_011511582.1 kalirin isoform X3
- UniProtKB/TrEMBL
-
H7BXZ5
- Conserved Domains (16) summary
-
- cd00096
Location:2489 → 2563
- Ig; Immunoglobulin domain
- cd11852
Location:1651 → 1710
- SH3_Kalirin_1; First Src homology 3 domain of the RhoGEF kinase, Kalirin
- cd11853
Location:2326 → 2384
- SH3_Kalirin_2; Second Src homology 3 domain of the RhoGEF kinase, Kalirin
- smart00220
Location:2685 → 2939
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- smart00516
Location:41 → 179
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00063
Location:2570 → 2661
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd00160
Location:1286 → 1456
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:893 → 1131
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam07679
Location:2472 → 2566
- I-set; Immunoglobulin I-set domain
- cd13240
Location:1463 → 1585
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- cd13241
Location:2108 → 2242
- PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
- cd14115
Location:2691 → 2938
- STKc_Kalirin_C; C-terminal kinase domain of the Large Serine/Threonine Kinase and Rho Guanine Nucleotide Exchange Factor, Kalirin
- pfam00169
Location:1496 → 1581
- PH; PH domain
- pfam00621
Location:1934 → 2104
- RhoGEF; RhoGEF domain
- pfam16609
Location:1708 → 1933
- SH3-RhoG_link; SH3-RhoGEF linking unstructured region
- cl02488
Location:1101 → 1240
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_017007430.2 → XP_016862919.1 kalirin isoform X12
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_006713811.4 → XP_006713874.1 kalirin isoform X4
- UniProtKB/TrEMBL
-
H7BXZ5
- Conserved Domains (16) summary
-
- cd00096
Location:2481 → 2555
- Ig; Immunoglobulin domain
- cd11852
Location:1642 → 1701
- SH3_Kalirin_1; First Src homology 3 domain of the RhoGEF kinase, Kalirin
- cd11853
Location:2318 → 2376
- SH3_Kalirin_2; Second Src homology 3 domain of the RhoGEF kinase, Kalirin
- smart00220
Location:2677 → 2931
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- smart00516
Location:41 → 179
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00063
Location:2562 → 2653
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd00160
Location:1277 → 1447
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:893 → 1122
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam07679
Location:2464 → 2558
- I-set; Immunoglobulin I-set domain
- cd13240
Location:1454 → 1576
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- cd13241
Location:2100 → 2234
- PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
- cd14115
Location:2683 → 2930
- STKc_Kalirin_C; C-terminal kinase domain of the Large Serine/Threonine Kinase and Rho Guanine Nucleotide Exchange Factor, Kalirin
- pfam00169
Location:1487 → 1572
- PH; PH domain
- pfam00621
Location:1926 → 2096
- RhoGEF; RhoGEF domain
- pfam16609
Location:1699 → 1925
- SH3-RhoG_link; SH3-RhoGEF linking unstructured region
- cl02488
Location:1124 → 1293
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_006713812.4 → XP_006713875.1 kalirin isoform X6
- UniProtKB/TrEMBL
-
H7BXZ5
- Conserved Domains (16) summary
-
- cd00096
Location:2477 → 2551
- Ig; Immunoglobulin domain
- cd11852
Location:1638 → 1697
- SH3_Kalirin_1; First Src homology 3 domain of the RhoGEF kinase, Kalirin
- cd11853
Location:2314 → 2372
- SH3_Kalirin_2; Second Src homology 3 domain of the RhoGEF kinase, Kalirin
- smart00220
Location:2673 → 2927
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- smart00516
Location:41 → 179
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00063
Location:2558 → 2649
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd00160
Location:1273 → 1443
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:539 → 755
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam07679
Location:2460 → 2554
- I-set; Immunoglobulin I-set domain
- cd13240
Location:1450 → 1572
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- cd13241
Location:2096 → 2230
- PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
- cd14115
Location:2679 → 2926
- STKc_Kalirin_C; C-terminal kinase domain of the Large Serine/Threonine Kinase and Rho Guanine Nucleotide Exchange Factor, Kalirin
- pfam00169
Location:1483 → 1568
- PH; PH domain
- pfam00621
Location:1922 → 2092
- RhoGEF; RhoGEF domain
- pfam16609
Location:1695 → 1921
- SH3-RhoG_link; SH3-RhoGEF linking unstructured region
- cl02488
Location:1088 → 1227
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047449159.1 → XP_047305115.1 kalirin isoform X13
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_006713813.4 → XP_006713876.1 kalirin isoform X9
- UniProtKB/TrEMBL
-
H7BXZ5
- Conserved Domains (16) summary
-
- cd00096
Location:2468 → 2542
- Ig; Immunoglobulin domain
- cd11852
Location:1629 → 1688
- SH3_Kalirin_1; First Src homology 3 domain of the RhoGEF kinase, Kalirin
- cd11853
Location:2305 → 2363
- SH3_Kalirin_2; Second Src homology 3 domain of the RhoGEF kinase, Kalirin
- smart00220
Location:2664 → 2918
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- smart00516
Location:41 → 179
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00063
Location:2549 → 2640
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd00160
Location:1264 → 1434
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:880 → 1109
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam07679
Location:2451 → 2545
- I-set; Immunoglobulin I-set domain
- cd13240
Location:1441 → 1563
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- cd13241
Location:2087 → 2221
- PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
- cd14115
Location:2670 → 2917
- STKc_Kalirin_C; C-terminal kinase domain of the Large Serine/Threonine Kinase and Rho Guanine Nucleotide Exchange Factor, Kalirin
- pfam00169
Location:1474 → 1559
- PH; PH domain
- pfam00621
Location:1913 → 2083
- RhoGEF; RhoGEF domain
- pfam16609
Location:1686 → 1912
- SH3-RhoG_link; SH3-RhoGEF linking unstructured region
- cl02488
Location:1111 → 1280
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_011513283.3 → XP_011511585.1 kalirin isoform X16
- UniProtKB/TrEMBL
-
A0A1S5UZ29
- Conserved Domains (11) summary
-
- cd11852
Location:1651 → 1710
- SH3_Kalirin_1; First Src homology 3 domain of the RhoGEF kinase, Kalirin
- cd11853
Location:2327 → 2385
- SH3_Kalirin_2; Second Src homology 3 domain of the RhoGEF kinase, Kalirin
- smart00516
Location:41 → 179
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:1286 → 1456
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:539 → 720
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd13240
Location:1463 → 1585
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- cd13241
Location:2109 → 2243
- PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
- pfam00169
Location:1496 → 1581
- PH; PH domain
- pfam00621
Location:1935 → 2105
- RhoGEF; RhoGEF domain
- pfam16609
Location:1708 → 1934
- SH3-RhoG_link; SH3-RhoGEF linking unstructured region
- cl02488
Location:1101 → 1240
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047449161.1 → XP_047305117.1 kalirin isoform X15
- UniProtKB/TrEMBL
-
A0A1S5UZ29
-
XM_047449160.1 → XP_047305116.1 kalirin isoform X14
- UniProtKB/TrEMBL
-
A0A1S5UZ29
-
XM_047449162.1 → XP_047305118.1 kalirin isoform X17
- UniProtKB/TrEMBL
-
A0A1S5UZ29
-
XM_024453811.2 → XP_024309579.1 kalirin isoform X18
- UniProtKB/TrEMBL
-
A0A1S5UZ29
- Related
-
ENST00000683592.1
- Conserved Domains (10) summary
-
- smart00150
Location:1128 → 1228
- SPEC; Spectrin repeats
- cd11852
Location:1642 → 1701
- SH3_Kalirin_1; First Src homology 3 domain of the RhoGEF kinase, Kalirin
- cd11853
Location:2284 → 2342
- SH3_Kalirin_2; Second Src homology 3 domain of the RhoGEF kinase, Kalirin
- smart00516
Location:41 → 179
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:1277 → 1447
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:893 → 1122
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd13240
Location:1454 → 1576
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- cd13241
Location:2067 → 2201
- PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
- pfam00621
Location:1893 → 2062
- RhoGEF; RhoGEF domain
- pfam16609
Location:1699 → 1855
- SH3-RhoG_link; SH3-RhoGEF linking unstructured region
-
XM_047449163.1 → XP_047305119.1 kalirin isoform X19
- UniProtKB/TrEMBL
-
A0A1S5UZ29
-
XM_017007434.3 → XP_016862923.1 kalirin isoform X21
-
XM_017007435.3 → XP_016862924.1 kalirin isoform X22
-
XM_047449165.1 → XP_047305121.1 kalirin isoform X23
-
XM_011513281.4 → XP_011511583.1 kalirin isoform X5
- UniProtKB/TrEMBL
-
H7BXZ5
- Related
- ENSP00000346122.4, ENST00000354186.8
- Conserved Domains (16) summary
-
- cd00096
Location:2479 → 2553
- Ig; Immunoglobulin domain
- cd11852
Location:1640 → 1699
- SH3_Kalirin_1; First Src homology 3 domain of the RhoGEF kinase, Kalirin
- cd11853
Location:2316 → 2374
- SH3_Kalirin_2; Second Src homology 3 domain of the RhoGEF kinase, Kalirin
- smart00220
Location:2675 → 2929
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- smart00516
Location:39 → 177
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00063
Location:2560 → 2651
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd00160
Location:1275 → 1445
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:891 → 1120
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam07679
Location:2462 → 2556
- I-set; Immunoglobulin I-set domain
- cd13240
Location:1452 → 1574
- PH1_Kalirin_Trio_like; Triple functional domain pleckstrin homology pleckstrin homology (PH) domain, repeat 1
- cd13241
Location:2098 → 2232
- PH2_Kalirin_Trio_p63RhoGEF; p63RhoGEF pleckstrin homology (PH) domain, repeat 2
- cd14115
Location:2681 → 2928
- STKc_Kalirin_C; C-terminal kinase domain of the Large Serine/Threonine Kinase and Rho Guanine Nucleotide Exchange Factor, Kalirin
- pfam00169
Location:1485 → 1570
- PH; PH domain
- pfam00621
Location:1924 → 2094
- RhoGEF; RhoGEF domain
- pfam16609
Location:1697 → 1923
- SH3-RhoG_link; SH3-RhoGEF linking unstructured region
- cl02488
Location:1122 → 1291
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047449164.1 → XP_047305120.1 kalirin isoform X20
Alternate T2T-CHM13v2.0
Genomic
-
NC_060927.1 Alternate T2T-CHM13v2.0
- Range
-
126759499..127452146
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054348294.1 → XP_054204269.1 kalirin isoform X1
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_054348300.1 → XP_054204275.1 kalirin isoform X7
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_054348295.1 → XP_054204270.1 kalirin isoform X2
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_054348301.1 → XP_054204276.1 kalirin isoform X8
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_054348303.1 → XP_054204278.1 kalirin isoform X10
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_054348304.1 → XP_054204279.1 kalirin isoform X11
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_054348296.1 → XP_054204271.1 kalirin isoform X3
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_054348305.1 → XP_054204280.1 kalirin isoform X12
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_054348297.1 → XP_054204272.1 kalirin isoform X4
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_054348299.1 → XP_054204274.1 kalirin isoform X6
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_054348306.1 → XP_054204281.1 kalirin isoform X13
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_054348302.1 → XP_054204277.1 kalirin isoform X9
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_054348309.1 → XP_054204284.1 kalirin isoform X16
- UniProtKB/TrEMBL
-
A0A1S5UZ29
-
XM_054348308.1 → XP_054204283.1 kalirin isoform X15
- UniProtKB/TrEMBL
-
A0A1S5UZ29
-
XM_054348307.1 → XP_054204282.1 kalirin isoform X14
- UniProtKB/TrEMBL
-
A0A1S5UZ29
-
XM_054348310.1 → XP_054204285.1 kalirin isoform X17
- UniProtKB/TrEMBL
-
A0A1S5UZ29
-
XM_054348311.1 → XP_054204286.1 kalirin isoform X18
- UniProtKB/TrEMBL
-
A0A1S5UZ29
-
XM_054348312.1 → XP_054204287.1 kalirin isoform X19
- UniProtKB/TrEMBL
-
A0A1S5UZ29
-
XM_054348314.1 → XP_054204289.1 kalirin isoform X21
-
XM_054348315.1 → XP_054204290.1 kalirin isoform X22
-
XM_054348316.1 → XP_054204291.1 kalirin isoform X23
-
XM_054348298.1 → XP_054204273.1 kalirin isoform X5
- UniProtKB/TrEMBL
-
H7BXZ5
-
XM_054348313.1 → XP_054204288.1 kalirin isoform X20