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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029111.2 RefSeqGene
- Range
-
5000..279283
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001321309.2 → NP_001308238.1 myosin light chain kinase, smooth muscle isoform 9
Status: REVIEWED
- Source sequence(s)
-
AC020634, AC023165, AC117381, AY339601, BC064695, BC113458, BQ006428, DA853780, U48959
- UniProtKB/TrEMBL
-
A0A8I5QKL9
- Conserved Domains (9) summary
-
- cd00096
Location:464 → 533
- Ig; Immunoglobulin domain
- cd05762
Location:1062 → 1159
- Ig8_MLCK; Eighth immunoglobulin (Ig)-like domain of human myosin light-chain kinase (MLCK)
- smart00408
Location:1646 → 1713
- IGc2; Immunoglobulin C-2 Type
- cd00063
Location:1155 → 1247
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam07679
Location:1633 → 1723
- I-set; Immunoglobulin I-set domain
- cd14191
Location:1285 → 1543
- STKc_MLCK1; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 1
- pfam00069
Location:1288 → 1543
- Pkinase; Protein kinase domain
- pfam16620
Location:75 → 236
- 23ISL; Unstructured linker between I-set domains 2 and 3 on MYLCK
- cl11960
Location:548 → 633
- Ig; Immunoglobulin domain
-
NM_053025.4 → NP_444253.3 myosin light chain kinase, smooth muscle isoform 1
See identical proteins and their annotated locations for NP_444253.3
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) is the full-length transcript and encodes the full-length nonmuscle isoform.
- Source sequence(s)
-
AC020634, AC023165, AC117381, AY339601, BC064420, BC064695, U48959
- Consensus CDS
-
CCDS46896.1
- UniProtKB/Swiss-Prot
- B4DUE3, D3DN97, O95796, O95797, O95798, O95799, Q14844, Q15746, Q16794, Q17S15, Q3ZCP9, Q5MY99, Q5MYA0, Q6P2N0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UBY6, Q9UIT9
- UniProtKB/TrEMBL
-
A0A8I5QKL9
- Related
- ENSP00000353452.3, ENST00000360304.8
- Conserved Domains (5) summary
-
- cd05762
Location:1238 → 1335
- Ig8_hMLCK_like; Eighth immunoglobulin (Ig)-like domain of human myosin light-chain kinase (MLCK) and similar domains
- cd00063
Location:1331 → 1423
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam07679
Location:1809 → 1899
- I-set; Immunoglobulin I-set domain
- cd14191
Location:1461 → 1719
- STKc_MLCK1; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 1
- pfam16620
Location:251 → 412
- 23ISL; Unstructured linker between I-set domains 2 and 3 on MYLCK
-
NM_053026.4 → NP_444254.3 myosin light chain kinase, smooth muscle isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) does not utilize exon 11, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1.
- Source sequence(s)
-
AC020634, AC023165, AC117381, AY339601, BC064420, BC064695, U48959
- Consensus CDS
-
CCDS43141.1
- UniProtKB/TrEMBL
-
A0A8I5QKL9
- Related
- ENSP00000510503.1, ENST00000693689.1
- Conserved Domains (5) summary
-
- cd05762
Location:1169 → 1266
- Ig8_hMLCK_like; Eighth immunoglobulin (Ig)-like domain of human myosin light-chain kinase (MLCK) and similar domains
- cd00063
Location:1262 → 1354
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam07679
Location:1740 → 1830
- I-set; Immunoglobulin I-set domain
- cd14191
Location:1392 → 1650
- STKc_MLCK1; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 1
- pfam16620
Location:251 → 412
- 23ISL; Unstructured linker between I-set domains 2 and 3 on MYLCK
-
NM_053027.4 → NP_444255.3 myosin light chain kinase, smooth muscle isoform 3A
Status: REVIEWED
- Description
- Transcript Variant: This variant (3A) does not utilize exon 30, compared to variant 1, resulting in a shorter protein (isoform 3A), compared to isoform 1.
- Source sequence(s)
-
AC020634, AC023165, AC117381, AY339601, BC064420, BC064695, U48959
- Consensus CDS
-
CCDS3023.1
- UniProtKB/TrEMBL
-
A0A8I5QKL9
- Related
- ENSP00000354004.3, ENST00000360772.7
- Conserved Domains (9) summary
-
- cd00096
Location:640 → 709
- Ig; Immunoglobulin domain
- cd05762
Location:1238 → 1335
- Ig8_MLCK; Eighth immunoglobulin (Ig)-like domain of human myosin light-chain kinase (MLCK)
- smart00408
Location:1771 → 1838
- IGc2; Immunoglobulin C-2 Type
- cd00063
Location:1331 → 1423
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam07679
Location:1758 → 1848
- I-set; Immunoglobulin I-set domain
- pfam00069
Location:1464 → 1668
- Pkinase; Protein kinase domain
- pfam16620
Location:251 → 412
- 23ISL; Unstructured linker between I-set domains 2 and 3 on MYLCK
- cl11960
Location:724 → 809
- Ig; Immunoglobulin domain
- cl21453
Location:1461 → 1668
- PKc_like; Protein Kinases, catalytic domain
-
NM_053028.4 → NP_444256.3 myosin light chain kinase, smooth muscle isoform 3B
Status: REVIEWED
- Description
- Transcript Variant: This variant (3B) does not utilize exons 11 and 30, compared to variant 1, resulting in a shorter protein (isoform 3B), compared to isoform 1.
- Source sequence(s)
-
AC020634, AC023165, AC117381, AY339601, BC064420, BC064695, U48959
- Consensus CDS
-
CCDS93356.1
- UniProtKB/TrEMBL
-
A0A8I5QKL9
- Related
- ENSP00000320622.6, ENST00000346322.10
- Conserved Domains (9) summary
-
- cd00096
Location:571 → 640
- Ig; Immunoglobulin domain
- cd05762
Location:1169 → 1266
- Ig8_MLCK; Eighth immunoglobulin (Ig)-like domain of human myosin light-chain kinase (MLCK)
- smart00408
Location:1702 → 1769
- IGc2; Immunoglobulin C-2 Type
- cd00063
Location:1262 → 1354
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam07679
Location:1689 → 1779
- I-set; Immunoglobulin I-set domain
- pfam00069
Location:1395 → 1599
- Pkinase; Protein kinase domain
- pfam16620
Location:251 → 412
- 23ISL; Unstructured linker between I-set domains 2 and 3 on MYLCK
- cl11960
Location:655 → 740
- Ig; Immunoglobulin domain
- cl21453
Location:1392 → 1599
- PKc_like; Protein Kinases, catalytic domain
-
NM_053031.4 → NP_444259.1 myosin light chain kinase, smooth muscle isoform 7
See identical proteins and their annotated locations for NP_444259.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) encodes the shorter isoform of kinase related protein, telokin. The first exon corresponds to intron 30 and the remainder of the transcript corresponds to the last two exons of the gene. It is shorter than variant 8 by one codon at the splicing junction between the first two exons.
- Source sequence(s)
-
AC023165, BC064420, BC113458, DB016380
- Consensus CDS
-
CCDS58849.1
- UniProtKB/TrEMBL
-
Q05B97
- Related
- ENSP00000510047.1, ENST00000685744.1
- Conserved Domains (1) summary
-
- cd20973
Location:51 → 138
- IgI_telokin-like; immunoglobulin-like domain of telokin and similar proteins; a member of the I-set of IgSF domains
-
NM_053032.4 → NP_444260.1 myosin light chain kinase, smooth muscle isoform 8
See identical proteins and their annotated locations for NP_444260.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (8) encodes the longer isoform of kinase related protein, telokin. It is longer than variant 7 by one codon at the splicing junction between the first two exons.
- Source sequence(s)
-
AC023165, BC064420, BC113456, DB016380
- Consensus CDS
-
CCDS46897.1
- UniProtKB/TrEMBL
-
Q05B97
- Related
- ENSP00000428967.1, ENST00000418370.6
- Conserved Domains (1) summary
-
- cd20973
Location:52 → 139
- IgI_telokin-like; immunoglobulin-like domain of telokin and similar proteins; a member of the I-set of IgSF domains
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000003.12 Reference GRCh38.p14 Primary Assembly
- Range
-
123610049..123884332 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047448184.1 → XP_047304140.1 myosin light chain kinase, smooth muscle isoform X7
- UniProtKB/Swiss-Prot
- B4DUE3, D3DN97, O95796, O95797, O95798, O95799, Q14844, Q15746, Q16794, Q17S15, Q3ZCP9, Q5MY99, Q5MYA0, Q6P2N0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UBY6, Q9UIT9
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_024453532.2 → XP_024309300.1 myosin light chain kinase, smooth muscle isoform X6
- UniProtKB/TrEMBL
- A0A8I5KU53, A0A8I5QKL9
- Related
- ENSP00000508761.1, ENST00000687848.1
- Conserved Domains (5) summary
-
- cd05762
Location:1248 → 1345
- Ig8_hMLCK_like; Eighth immunoglobulin (Ig)-like domain of human myosin light-chain kinase (MLCK) and similar domains
- cd00063
Location:1341 → 1433
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam07679
Location:1819 → 1909
- I-set; Immunoglobulin I-set domain
- cd14191
Location:1471 → 1729
- STKc_MLCK1; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 1
- pfam16620
Location:261 → 422
- 23ISL; Unstructured linker between I-set domains 2 and 3 on MYLCK
-
XM_047448183.1 → XP_047304139.1 myosin light chain kinase, smooth muscle isoform X6
- UniProtKB/TrEMBL
- A0A8I5KU53, A0A8I5QKL9
-
XM_047448187.1 → XP_047304143.1 myosin light chain kinase, smooth muscle isoform X6
- UniProtKB/TrEMBL
- A0A8I5KU53, A0A8I5QKL9
-
XM_047448186.1 → XP_047304142.1 myosin light chain kinase, smooth muscle isoform X8
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_017006469.3 → XP_016861958.2 myosin light chain kinase, smooth muscle isoform X5
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_024453534.2 → XP_024309302.1 myosin light chain kinase, smooth muscle isoform X3
- UniProtKB/TrEMBL
-
A0A8I5QKL9
- Related
- ENSP00000508777.1, ENST00000690457.1
- Conserved Domains (5) summary
-
- cd05762
Location:1179 → 1276
- Ig8_hMLCK_like; Eighth immunoglobulin (Ig)-like domain of human myosin light-chain kinase (MLCK) and similar domains
- cd00063
Location:1272 → 1364
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam07679
Location:1750 → 1840
- I-set; Immunoglobulin I-set domain
- cd14191
Location:1402 → 1660
- STKc_MLCK1; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 1
- pfam16620
Location:261 → 422
- 23ISL; Unstructured linker between I-set domains 2 and 3 on MYLCK
-
XM_047448182.1 → XP_047304138.1 myosin light chain kinase, smooth muscle isoform X4
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_011512861.4 → XP_011511163.2 myosin light chain kinase, smooth muscle isoform X2
- UniProtKB/TrEMBL
-
A0A8I5QKL9
- Conserved Domains (5) summary
-
- cd05762
Location:1248 → 1345
- Ig8_hMLCK_like; Eighth immunoglobulin (Ig)-like domain of human myosin light-chain kinase (MLCK) and similar domains
- cd00063
Location:1341 → 1433
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam07679
Location:1751 → 1841
- I-set; Immunoglobulin I-set domain
- pfam16620
Location:261 → 422
- 23ISL; Unstructured linker between I-set domains 2 and 3 on MYLCK
- cl21453
Location:1483 → 1661
- PKc_like; Protein Kinases, catalytic domain
-
XM_011512860.4 → XP_011511162.2 myosin light chain kinase, smooth muscle isoform X1
- UniProtKB/TrEMBL
-
A0A8I5QKL9
- Conserved Domains (5) summary
-
- cd05762
Location:1248 → 1345
- Ig8_hMLCK_like; Eighth immunoglobulin (Ig)-like domain of human myosin light-chain kinase (MLCK) and similar domains
- cd00063
Location:1341 → 1433
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam07679
Location:1818 → 1908
- I-set; Immunoglobulin I-set domain
- cd14191
Location:1471 → 1729
- STKc_MLCK1; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 1
- pfam16620
Location:261 → 422
- 23ISL; Unstructured linker between I-set domains 2 and 3 on MYLCK
-
XM_024453537.2 → XP_024309305.1 myosin light chain kinase, smooth muscle isoform X7
- UniProtKB/Swiss-Prot
- B4DUE3, D3DN97, O95796, O95797, O95798, O95799, Q14844, Q15746, Q16794, Q17S15, Q3ZCP9, Q5MY99, Q5MYA0, Q6P2N0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UBY6, Q9UIT9
- UniProtKB/TrEMBL
-
A0A8I5QKL9
- Related
- ENSP00000508758.1, ENST00000686761.1
- Conserved Domains (5) summary
-
- cd05762
Location:1238 → 1335
- Ig8_hMLCK_like; Eighth immunoglobulin (Ig)-like domain of human myosin light-chain kinase (MLCK) and similar domains
- cd00063
Location:1331 → 1423
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam07679
Location:1809 → 1899
- I-set; Immunoglobulin I-set domain
- cd14191
Location:1461 → 1719
- STKc_MLCK1; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 1
- pfam16620
Location:251 → 412
- 23ISL; Unstructured linker between I-set domains 2 and 3 on MYLCK
-
XM_047448185.1 → XP_047304141.1 myosin light chain kinase, smooth muscle isoform X7
- UniProtKB/Swiss-Prot
- B4DUE3, D3DN97, O95796, O95797, O95798, O95799, Q14844, Q15746, Q16794, Q17S15, Q3ZCP9, Q5MY99, Q5MYA0, Q6P2N0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UBY6, Q9UIT9
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_047448188.1 → XP_047304144.1 myosin light chain kinase, smooth muscle isoform X11
-
XM_017006470.3 → XP_016861959.1 myosin light chain kinase, smooth muscle isoform X10
- UniProtKB/TrEMBL
-
A0A8I5KTQ1
- Related
- ENSP00000510593.1, ENST00000685953.1
-
XM_017006471.3 → XP_016861960.1 myosin light chain kinase, smooth muscle isoform X9
- UniProtKB/Swiss-Prot
-
Q15746
- Related
- ENSP00000422984.2, ENST00000508240.2
- Conserved Domains (4) summary
-
- cd00063
Location:131 → 223
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd05762
Location:37 → 135
- IgI_8_hMLCK_like; Eighth immunoglobulin (Ig)-like domain of human myosin light-chain kinase (MLCK) and similar protein; member of the I-set of IgSF domains
- cd20973
Location:612 → 699
- IgI_telokin-like; immunoglobulin-like domain of telokin and similar proteins; a member of the I-set of IgSF domains
- cl21453
Location:261 → 519
- PKc_like; Protein Kinases, catalytic domain
-
XM_017006473.2 → XP_016861962.1 myosin light chain kinase, smooth muscle isoform X13
- UniProtKB/TrEMBL
-
Q05B97
- Related
- ENSP00000509867.1, ENST00000687375.1
- Conserved Domains (1) summary
-
- cd20973
Location:51 → 138
- IgI_telokin-like; immunoglobulin-like domain of telokin and similar proteins; a member of the I-set of IgSF domains
-
XM_017006472.3 → XP_016861961.1 myosin light chain kinase, smooth muscle isoform X12
- UniProtKB/TrEMBL
-
Q05B97
- Related
- ENSP00000462118.1, ENST00000583087.6
- Conserved Domains (1) summary
-
- cd20973
Location:52 → 139
- IgI_telokin-like; immunoglobulin-like domain of telokin and similar proteins; a member of the I-set of IgSF domains
Alternate T2T-CHM13v2.0
Genomic
-
NC_060927.1 Alternate T2T-CHM13v2.0
- Range
-
126330173..126610461 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054346621.1 → XP_054202596.1 myosin light chain kinase, smooth muscle isoform X7
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_054346619.1 → XP_054202594.1 myosin light chain kinase, smooth muscle isoform X6
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_054346625.1 → XP_054202600.1 myosin light chain kinase, smooth muscle isoform X6
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_054346616.1 → XP_054202591.1 myosin light chain kinase, smooth muscle isoform X4
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_054346614.1 → XP_054202589.1 myosin light chain kinase, smooth muscle isoform X2
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_054346612.1 → XP_054202587.1 myosin light chain kinase, smooth muscle isoform X1
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_054346624.1 → XP_054202599.1 myosin light chain kinase, smooth muscle isoform X8
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_054346617.1 → XP_054202592.1 myosin light chain kinase, smooth muscle isoform X5
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_054346613.1 → XP_054202588.1 myosin light chain kinase, smooth muscle isoform X7
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_054346618.1 → XP_054202593.1 myosin light chain kinase, smooth muscle isoform X14
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_054346615.1 → XP_054202590.1 myosin light chain kinase, smooth muscle isoform X3
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_054346622.1 → XP_054202597.1 myosin light chain kinase, smooth muscle isoform X7
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_054346620.1 → XP_054202595.1 myosin light chain kinase, smooth muscle isoform X6
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_054346623.1 → XP_054202598.1 myosin light chain kinase, smooth muscle isoform X7
- UniProtKB/TrEMBL
-
A0A8I5QKL9
-
XM_054346628.1 → XP_054202603.1 myosin light chain kinase, smooth muscle isoform X9
-
XM_054346627.1 → XP_054202602.1 myosin light chain kinase, smooth muscle isoform X11
-
XM_054346626.1 → XP_054202601.1 myosin light chain kinase, smooth muscle isoform X10
- UniProtKB/TrEMBL
-
A0A8I5KTQ1
-
XM_054346630.1 → XP_054202605.1 myosin light chain kinase, smooth muscle isoform X13
- UniProtKB/TrEMBL
-
Q05B97
-
XM_054346629.1 → XP_054202604.1 myosin light chain kinase, smooth muscle isoform X12
- UniProtKB/TrEMBL
-
Q05B97
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_005965.3: Suppressed sequence
- Description
- NM_005965.3: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
-
NM_053029.2: Suppressed sequence
- Description
- NM_053029.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
-
NM_053030.2: Suppressed sequence
- Description
- NM_053030.2: This RefSeq was permanently suppressed because there was insufficient support for the transcript and the CDS was partial.