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    tufm Tu translation elongation factor, mitochondrial [ Danio rerio (zebrafish) ]

    Gene ID: 541378, updated on 2-Nov-2024

    Summary

    Official Symbol
    tufmprovided by ZNC
    Official Full Name
    Tu translation elongation factor, mitochondrialprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050320-73
    See related
    Ensembl:ENSDARG00000104173 AllianceGenome:ZFIN:ZDB-GENE-050320-73
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    D250; fi06f04; wu:fi06f04; zgc:110766
    Summary
    Predicted to enable translation elongation factor activity. Predicted to be involved in mitochondrial translational elongation. Predicted to act upstream of or within translational elongation. Predicted to be active in mitochondrion. Is expressed in several structures, including alar plate midbrain region; digestive system; optic tectum; pectoral fin bud; and segmental plate. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 4. Orthologous to human TUFM (Tu translation elongation factor, mitochondrial). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See tufm in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (13582019..13599471, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (13432173..13449625, complement)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108182805 Neighboring gene noggin 5 Neighboring gene HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 Neighboring gene peptidoglycan recognition protein 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables translation elongation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables translation elongation factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial translational elongation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within translational elongation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    elongation factor Tu, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013505.2NP_001013523.1  elongation factor Tu, mitochondrial

      See identical proteins and their annotated locations for NP_001013523.1

      Status: PROVISIONAL

      Source sequence(s)
      BC091659
      UniProtKB/TrEMBL
      B2GSN2, Q5BJ17
      Related
      ENSDARP00000134914.1, ENSDART00000166639.2
      Conserved Domains (4) summary
      cd01884
      Location:51245
      EF_Tu; Elongation Factor Tu (EF-Tu) GTP-binding proteins
      PRK00049
      Location:42435
      PRK00049; elongation factor Tu; Reviewed
      cd03697
      Location:253339
      EFTU_II; Domain II of elongation factor Tu
      cd03706
      Location:342434
      mtEFTU_III; Domain III of mitochondrial EF-TU (mtEF-TU)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      13582019..13599471 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)