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    adipor1a adiponectin receptor 1a [ Danio rerio (zebrafish) ]

    Gene ID: 436740, updated on 4-Jan-2025

    Summary

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    Official Symbol
    adipor1aprovided by ZNC
    Official Full Name
    adiponectin receptor 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-169
    See related
    Ensembl:ENSDARG00000002912 AllianceGenome:ZFIN:ZDB-GENE-040718-169
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    adipor1; zgc:92893
    Summary
    Predicted to enable signaling receptor activity. Predicted to be involved in adiponectin-activated signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; digestive system; eye; fat cell; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in breast cancer; macular degeneration; and prostate adenocarcinoma. Orthologous to human ADIPOR1 (adiponectin receptor 1). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See adipor1a in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (24800070..24814539)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (24562454..24576923)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene arginyl aminopeptidase (aminopeptidase B) Neighboring gene cytochrome b5 reductase 1 Neighboring gene RAB interacting factor Neighboring gene lysine demethylase 5Ba

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Identification, characterization, and expression analysis of adiponectin receptors in black carp Mylopharyngodon piceus in response to dietary carbohydrate. Wu C, et al. Fish Physiol Biochem, 2018 Aug. PMID 29687170
    2. Expression of adiponectin receptors in the brain of adult zebrafish and mouse: Links with neurogenic niches and brain repair. Rastegar S, et al. J Comp Neurol, 2019 Oct 1. PMID 30843204
    3. Bis(2-ethylhexyl)-tetrabromophthalate induces zebrafish obesity by altering the brain-gut axis and intestinal microbial composition. Zhou Y, et al. Environ Pollut, 2021 Dec 1. PMID 34523534
    4. Ribosome profiling shows that miR-430 reduces translation before causing mRNA decay in zebrafish. Bazzini AA, et al. Science, 2012 Apr 13. PMID 22422859, Free PMC Article
    5. Adiponectin and adiponectin receptor genes are coexpressed during zebrafish embryogenesis and regulated by food deprivation. Nishio S, et al. Dev Dyn, 2008 Jun. PMID 18489000

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Expression of adiponectin receptors in the brain of adult zebrafish and mouse: Links with neurogenic niches and brain repair.
      Title: Expression of adiponectin receptors in the brain of adult zebrafish and mouse: Links with neurogenic niches and brain repair.
    2. Adiponectin and adiponectin receptor genes are coexpressed during zebrafish embryogenesis and regulated by food deprivation
      Title: Adiponectin and adiponectin receptor genes are coexpressed during zebrafish embryogenesis and regulated by food deprivation.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in adiponectin-activated signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    adiponectin receptor protein 1a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001327754.1 → NP_001314683.1  adiponectin receptor protein 1a

      Status: VALIDATED

      Source sequence(s)
      CR628365, CR812923, EH448747, EH474583, EH505010, EH578188, EH586253
      UniProtKB/TrEMBL
      A0A8M1P991, F1QJJ9
      Related
      ENSDARP00000114440.1, ENSDART00000131976.3
      Conserved Domains (1) summary
      pfam03006
      Location:129 → 352
      HlyIII; Haemolysin-III related

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      24800070..24814539
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394820.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      295152..309108
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394821.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      1..513
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001002467.1: Suppressed sequence

      Description
      NM_001002467.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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