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    ogt.2 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 2 [ Danio rerio (zebrafish) ]

    Gene ID: 652952, updated on 3-Dec-2024

    Summary

    Official Symbol
    ogt.2provided by ZNC
    Official Full Name
    O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-051128-1
    See related
    Ensembl:ENSDARG00000099455 AllianceGenome:ZFIN:ZDB-GENE-051128-1
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ogtb; ogtl
    Summary
    Enables protein N-acetylglucosaminyltransferase activity. Predicted to be involved in protein glycosylation. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 106. Orthologous to human OGT (O-linked N-acetylglucosamine (GlcNAc) transferase). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See ogt.2 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (14687721..14710837, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (14382158..14405227, complement)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene centrin, EF-hand protein, 2 Neighboring gene germ cell nuclear acidic peptidase Neighboring gene O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 Neighboring gene uncharacterized LOC137487515

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein N-acetylglucosaminyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables protein O-acetylglucosaminyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 2
    Names
    O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 2
    O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) like
    NP_001373727.1
    NP_001373728.1
    XP_021336805.1
    XP_068069340.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001386798.1NP_001373727.1  O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      BX323828, CR753843
      UniProtKB/TrEMBL
      A0A0R4IVJ0, A0A8M1QLF2
      Related
      ENSDARP00000130346.2, ENSDART00000159456.2
      Conserved Domains (3) summary
      TIGR02917
      Location:22465
      PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
      sd00006
      Location:327355
      TPR; TPR repeat [structural motif]
      pfam13844
      Location:4761014
      Glyco_transf_41; Glycosyl transferase family 41
    2. NM_001386799.1NP_001373728.1  O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      BX323828, CR753843
      UniProtKB/TrEMBL
      A0A8M2B3B2
      Related
      ENSDARP00000136590.2, ENSDART00000157392.2
      Conserved Domains (3) summary
      TIGR02917
      Location:23455
      PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
      sd00006
      Location:317345
      TPR; TPR repeat [structural motif]
      pfam13844
      Location:4661004
      Glyco_transf_41; Glycosyl transferase family 41

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      14687721..14710837 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068213239.1XP_068069340.1  O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B3B2
    2. XM_021481130.2XP_021336805.1  O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M9QPC9
      Conserved Domains (3) summary
      sd00006
      Location:151179
      TPR; TPR repeat [structural motif]
      pfam13844
      Location:380845
      Glyco_transf_41; Glycosyl transferase family 41
      cl26002
      Location:6289
      TPR_11; TPR repeat