ddx52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ddx52provided by ZNC
Official Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 52provided by ZNC
Primary source: ZFIN:ZDB-GENE-060623-1
See related: Ensembl:ENSDARG00000100505 AllianceGenome:ZFIN:ZDB-GENE-060623-1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable several functions, including ATP binding activity; RNA helicase activity; and nucleic acid binding activity. Acts upstream of or within fin regeneration and regulation of growth. Orthologous to human DDX52 (DExD-box helicase 52). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 21

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (38855551..38869404)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (38808066..38822004)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables RNA helicase activity	IEA Inferred from Electronic Annotation more info
enables helicase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within fin regeneration	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in maturation of SSU-rRNA	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within maturation of SSU-rRNA	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of growth	IMP Inferred from Mutant Phenotype more info	PubMed

General protein information

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Preferred Names: probable ATP-dependent RNA helicase DDX52

NP_001037780.2

EC 3.6.4.13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001044315.2 → NP_001037780.2 probable ATP-dependent RNA helicase DDX52

Status: VALIDATED

Source sequence(s)

CT698434, CT716534, EH493950, EH580775, LO018189

UniProtKB/TrEMBL

A0A0R4IJV5, A0A8M1N8X8

Related

ENSDARP00000133983.1, ENSDART00000171977.3

Conserved Domains (3) summary

PTZ00424
Location:141 → 546

PTZ00424; helicase 45; Provisional

pfam00271
Location:401 → 511

Helicase_C; Helicase conserved C-terminal domain

cl21455
Location:172 → 379

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases