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    arhgef16 Rho guanine nucleotide exchange factor (GEF) 16 [ Danio rerio (zebrafish) ]

    Gene ID: 567180, updated on 9-Dec-2024

    Summary

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    Official Symbol
    arhgef16provided by ZNC
    Official Full Name
    Rho guanine nucleotide exchange factor (GEF) 16provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-081104-446
    See related
    Ensembl:ENSDARG00000077114 AllianceGenome:ZFIN:ZDB-GENE-081104-446
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkeyp-100a1.3
    Summary
    Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of actin cytoskeleton organization. Orthologous to human ARHGEF16 (Rho guanine nucleotide exchange factor 16). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See arhgef16 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (47098992..47143911)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (47108503..47153360)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496385 Neighboring gene hes family bHLH transcription factor 2, tandem duplicate 1 Neighboring gene espin Neighboring gene espin-like protein Neighboring gene si:dkeyp-100a1.6 Neighboring gene Y box binding protein 1 Neighboring gene peptidylprolyl isomerase H (cyclophilin H) Neighboring gene uncharacterized LOC101883933

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    rho guanine nucleotide exchange factor 16

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001123283.1 → NP_001116755.1  rho guanine nucleotide exchange factor 16

      Status: PROVISIONAL

      Source sequence(s)
      BX000472, CR792439, CT573138
      UniProtKB/TrEMBL
      A0A8M1NIJ7, B0S4U0
      Related
      ENSDARP00000112801.1, ENSDART00000142979.3
      Conserved Domains (4) summary
      cd01221
      Location:438 → 559
      PH_ephexin; Ephexin Pleckstrin homology (PH) domain
      pfam00169
      Location:451 → 556
      PH; PH domain
      pfam00621
      Location:237 → 416
      RhoGEF; RhoGEF domain
      cl17036
      Location:568 → 598
      SH3; Src Homology 3 domain superfamily

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      47098992..47143911
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005167281.5 → XP_005167338.1  rho guanine nucleotide exchange factor 16 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BEQ4
      Conserved Domains (4) summary
      cd11938
      Location:586 → 639
      SH3_ARHGEF16_26; Src homology 3 domain of the Rho guanine nucleotide exchange factors ARHGEF16 and ARHGEF26
      cd01221
      Location:456 → 577
      PH_ephexin; Ephexin Pleckstrin homology (PH) domain
      pfam00169
      Location:469 → 574
      PH; PH domain
      pfam00621
      Location:255 → 434
      RhoGEF; RhoGEF domain
    Nucleotide Protein Strain
    Heading Accession and Version

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