gcat glycine C-acetyltransferase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gcatprovided by ZNC
Official Full Name: glycine C-acetyltransferaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-060518-3
See related: Ensembl:ENSDARG00000005643 AllianceGenome:ZFIN:ZDB-GENE-060518-3
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable glycine C-acetyltransferase activity; ligase activity; and pyridoxal phosphate binding activity. Predicted to act upstream of or within biosynthetic process and threonine catabolic process. Predicted to be active in mitochondrion. Orthologous to human GCAT (glycine C-acetyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (25990060..25998247)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (25859189..25867376)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glycine C-acetyltransferase activity	IEA Inferred from Electronic Annotation more info
enables ligase activity	IEA Inferred from Electronic Annotation more info
enables pyridoxal phosphate binding	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within threonine catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

NP_001166025.1

EC 2.3.1.29

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001172554.1 → NP_001166025.1 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

Status: VALIDATED

Source sequence(s)

BC067644, EB906064, EH467192

UniProtKB/TrEMBL

A0A8M1NT19, F6P2R4, Q6NWC4

Related

ENSDARP00000020361.6, ENSDART00000007398.7

Conserved Domains (2) summary

COG0156
Location:40 → 420

BioF; 7-keto-8-aminopelargonate synthetase or related enzyme [Coenzyme transport and metabolism]

PRK06939
Location:37 → 430

PRK06939; 2-amino-3-ketobutyrate coenzyme A ligase; Provisional